SHARE-BASED COMPENSATION (Tables)

9 Months Ended

Sep. 30, 2022

SHARE-BASED COMPENSATION

Summary of stock based compensation classified in the consolidated statements of operations

	Three Months Ended September 30,				Nine Months Ended September 30,
(In thousands)	2022		2021		2022		2021
Research and development	$	1	$	6	$	(9)	$	15
General and administrative		36		79		119		217
Total	$	37	$	85	$	110	$	232

Summary of option activity

				Weighted
		Weighted		Average
		Average		Remaining	Aggregate
		Exercise		Contractual	Intrinsic
Options	Shares	Price		Term in Years	Value
Outstanding at December 31, 2021	14,582	$	437.78	9.18		$	—
Cancelled/Forfeited	(1,213)	$	1,305.23
Outstanding as of September 30, 2022	13,369	$	359.07	8.42		$	—
Vested and Exercisable as of September 30, 2022	8,269	$	563.57	8.40		$	—
Vested and expected to vest as of September 30, 2022	13,369	$	359.07	8.42		$	—

Summary of restricted stock unit activity

The following table summarizes the restricted securities activity for the nine months ended September 30, 2022;

		Weighted-Average
Restricted Securities	Number of Grants	Grant Date Fair Value
Unvested balance as of December 31, 2021	254	$	387.05
Vested	(200)	$	387.50
Forfeited	(54)	$	385.38
Unvested balance as of September 30, 2022	—	$	—