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SHARE-BASED COMPENSATION, SHARE-BASED COMPENSATION (Details) - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2022
Mar. 31, 2021
Dec. 31, 2021
Dec. 31, 2020
Stock options        
Stock-based compensation (in dollars) $ 56 $ 52    
Expected term 10 years      
Vesting period 48 months      
Cumulative Adjustment on adoption of ASU 2016-09. $ 15,516 25,524 $ 18,115 $ 19,186
Research and development        
Stock options        
Stock-based compensation (in dollars) 6 3    
General and administrative        
Stock options        
Stock-based compensation (in dollars) 50 49    
Stock Options        
Stock options        
Stock-based compensation (in dollars) $ 48 $ 28