SHARE-BASED COMPENSATION, STOCK OPTIONS, AND RESTRICTED SECURITIES (Tables)

12 Months Ended

Dec. 31, 2021

SHARE-BASED COMPENSATION, STOCK OPTIONS, AND RESTRICTED SECURITIES

Summary of stock based compensation classified in the consolidated statements of operations

For the years ended December 31, 2021 and 2020, Stock-based compensation recognized was classified in the consolidated statements of operations as follows:

	Year Ended December 31,
(In thousands)	2021		2020
Research and development	$	22	$	40
General and administrative		293		175
Total	$	315	$	215

Schedule of assumptions used principally in determining the fair value of options granted

	December 31,
	2021
Risk-free interest rate	1.03%
Expected dividend yield	0%
Expected term (employee grants)	5.70
Expected volatility	117.34%

Summary of option activity

				Weighted
		Weighted		Average
		Average		Remaining	Aggregate
		Exercise		Contractual	Intrinsic
Options	Shares	Price		Term in Years	Value
Outstanding as of December 31, 2020	4,169	$	1,054.01	7.18		$	—
Granted	360,000	$	1.10
Cancelled/Forfeited	(147)	$	6,324.03
Expired	(17)	$	5,940.00
Outstanding as of December 31, 2021	364,005	$	10.33	9.18		$	—
Vested and Exercisable as of December 31, 2021	3,005	$	1,104.04	6.17		$	—
Vested and expected to vest as of December 31, 2021	364,005	$	10.33	9.18		$	—

Summary of restricted stock unit activity

		Weighted-Average
Restricted Securities	Number of Grants	Grant Date Fair Value
Unvested balance as of December 31, 2020	6,402	$	25.67
Vested	(100)	$	660.00
Unvested balance as of December 31, 2021	6,302	$	15.60