WARRANTS (Details) - $ / shares	3 Months Ended
	Mar. 31, 2021	Mar. 31, 2020
Warrants to purchase common stock issued and outstanding
Number of Warrants	14,078,349
Weighted average exercise price	$ 1.41
Weighted average life in years	4 years 4 months 28 days
Warrants 2014 [Member]
Warrants to purchase common stock issued and outstanding
Warrants Issued Year	2014
Number of Warrants	11
Warrant Exercise Price	$ 352.50
Expiration date	May 09, 2021
2018 Warrants {Member]
Warrants to purchase common stock issued and outstanding
Warrants Issued Year	2018
Number of Warrants	211,921
Warrant Exercise Price	$ 6.98
Expiration date	Jun. 25, 2023
Warrants 2019 [Member]
Warrants to purchase common stock issued and outstanding
Warrants Issued Year	2019
Number of Warrants	15,168
Warrant Exercise Price	$ 4.50
Expiration date	Nov. 21, 2024
Warrants 2020, First [Member]
Warrants to purchase common stock issued and outstanding
Warrants Issued Year	2020
Number of Warrants	2,545,455
Warrant Exercise Price	$ 2.75
Expiration date	Mar. 10, 2025
Warrants 2020, Second [Member]
Warrants to purchase common stock issued and outstanding
Warrants Issued Year	2020
Number of Warrants	165,455
Warrant Exercise Price	$ 3.4375
Expiration date	Mar. 05, 2025
Warrants 2020, Third [Member]
Warrants to purchase common stock issued and outstanding
Warrants Issued Year	2020
Number of Warrants	12,728
Warrant Exercise Price	$ 0.00001
Warrants 2020, Fourth [Member]
Warrants to purchase common stock issued and outstanding
Warrants Issued Year	2020
Number of Warrants	1,680,240
Warrant Exercise Price	$ 1.62
Expiration date	Oct. 17, 2025
Warrants 2020, Fifth [Member]
Warrants to purchase common stock issued and outstanding
Warrants Issued Year	2020
Number of Warrants	111,491
Warrant Exercise Price	$ 2.1875
Expiration date	Apr. 15, 2025
Placement Agent Warrants
Warrants to purchase common stock issued and outstanding
Warrants Issued Year	2020
Number of Warrants	1,206,562	165,455
Warrant Exercise Price	$ 1.00	$ 3.4375
Expiration date	Oct. 22, 2025
October 2020 Offering [Member]
Warrants to purchase common stock issued and outstanding
Warrants Issued Year	2020
Number of Warrants	8,129,318
Warrant Exercise Price	$ 0.80
Expiration date	Oct. 27, 2025