SHARE-BASED COMPENSATION, STOCK OPTIONS, AND RESTRICTED SECURITIES (Tables)

12 Months Ended

Dec. 31, 2020

SHARE-BASED COMPENSATION, STOCK OPTIONS, AND RESTRICTED SECURITIES

Summary of stock based compensation classified in the consolidated statements of operations

	Year Ended December 31,
(In thousands)	2020		2019
Research and development	$	40	$	94
General and administrative		175		174
Total	$	215	$	268

Schedule of assumptions used principally in determining the fair value of options granted

	December 31,
	2019
Risk-free interest rate	2.55%
Expected dividend yield	0%
Expected term (employee grants)	6 Years
Expected volatility	105%

Summary of option activity

				Weighted
		Weighted		Average
		Average		Remaining	Aggregate
		Exercise		Contractual	Intrinsic
Options	Shares	Price		Term in Years	Value
Outstanding at December 31, 2018	1,858	$	2,976.58	7.32		$	—
Granted	3,000	$	45.90
Expired	(85)	$	6,794.12
Cancelled/Forfeited	(586)	$	1,195.25
Outstanding at December 31, 2019	4,187	$	1,077.78	8.17		$	—
Expired	(17)	$	6,780.00
Cancelled/Forfeited	(1)	$	3,262.50
Outstanding at December 31, 2020	4,169	$	1,054.01	7.18		$	—
Vested and Exercisable at December 31, 2020	2,104	$	1,984.48	6.38		$	—
Vested and expected to vest at December 31, 2020	4,169	$	1,054.01	7.18	$		—

Summary of restricted stock unit activity

		Weighted-Average
Restricted Securities	Number of Grants	Grant Date Fair Value
Unvested balance at December 31, 2018	343	$	693.17
Granted	6,886		15.59
Vested/Released	(143)	$	734.70
Unvested balance at December 31, 2019	7,086	$	33.78
Vested	(100)	$	660.00
Forfeited	(584)	$	15.60
Unvested balance at December 31, 2020	6,402	$	25.67