SHARE-BASED COMPENSATION, STOCK OPTIONS, AND RESTRICTED SECURITIES (Tables)

12 Months Ended

Dec. 31, 2019

SHARE-BASED COMPENSATION, STOCK OPTIONS, AND RESTRICTED SECURITIES

Summary of stock based compensation classified in the consolidated statements of operations

(In thousands)	Year Ended December 31, 2019		Year Ended December 31, 2018
Research and development	$	94	$	183
General and administrative		174		435
Total	$	268	$	618

Schedule of assumptions used principally in determining the fair value of options granted

	December 31,	December 31,
	2019	2018
Risk-free interest rate	2.55%	2.45 - 2.88%
Expected dividend yield	0%	0%
Expected term (employee grants)	6 Years	5.62 Years
Expected volatility	105%	104%

Summary of option activity

				Weighted
		Weighted		Average
		Average		Remaining	Aggregate
		Exercise		Contractual	Intrinsic
Options	Shares	Price		Term in Years	Value
Outstanding at December 31, 2017	4,570	$	4,845.94	7.14	$	22
Granted	520	$	148.08
Expired	(180)	$	5,130.40
Cancelled/Forfeited	(3,052)	$	5,166.77
Outstanding at December 31, 2018	1,858	$	2,976.58	7.32	$	—
Granted	3,000	$	45.90
Expired	(85)	$	6,794.12
Cancelled/Forfeited	(586)	$	1,195.25
Outstanding at December 31, 2019	4,187	$	1,077.78	8.17	$	—
Vested and Exercisable at December 31, 2019	1,000	$	3,874.14	5.63	$	—

Summary of restricted stock unit activity

		Weighted-Average
Restricted Securities	Number of Grants	Grant Date Fair Value
Unvested balance at December 31, 2017	670	$	767.16
Granted	—		—
Vested/Released	(143)	$	734.70
Forfeited	(184)	$	934.10
Unvested balance at December 31, 2018	343	$	693.17
Granted	6,886	$	15.59
Vested	(143)	$	734.70
Unvested balance at December 31, 2019	7,086	$	33.78