<SEC-DOCUMENT>0001104659-20-115633-index.html : 20201016
<SEC-HEADER>0001104659-20-115633.hdr.sgml : 20201016
<ACCEPTANCE-DATETIME>20201016160248
ACCESSION NUMBER:		0001104659-20-115633
CONFORMED SUBMISSION TYPE:	S-1/A
PUBLIC DOCUMENT COUNT:		11
FILED AS OF DATE:		20201016
DATE AS OF CHANGE:		20201016

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			INVIVO THERAPEUTICS HOLDINGS CORP.
		CENTRAL INDEX KEY:			0001292519
		STANDARD INDUSTRIAL CLASSIFICATION:	SURGICAL & MEDICAL INSTRUMENTS & APPARATUS [3841]
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			NV
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		S-1/A
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-249353
		FILM NUMBER:		201244012

	BUSINESS ADDRESS:	
		STREET 1:		ONE KENDALL SQUARE
		STREET 2:		BUILDING 1400 EAST 4TH FLOOR
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02139
		BUSINESS PHONE:		617-863-5524

	MAIL ADDRESS:	
		STREET 1:		ONE KENDALL SQUARE
		STREET 2:		BUILDING 1400 EAST 4TH FLOOR
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02139

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Design Source, Inc.
		DATE OF NAME CHANGE:	20040602
</SEC-HEADER>
<DOCUMENT>
<TYPE>S-1/A
<SEQUENCE>1
<FILENAME>tm2032415-3_s1a.htm
<DESCRIPTION>S-1/A
<TEXT>
Document 1 - file: tm2032415-3_s1a.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-4.12
<SEQUENCE>2
<FILENAME>tm2032415d4_ex4-12.htm
<DESCRIPTION>EXHIBIT 4.12
<TEXT>
Document 2 - file: tm2032415d4_ex4-12.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-4.13
<SEQUENCE>3
<FILENAME>tm2032415d4_ex4-13.htm
<DESCRIPTION>EXHIBIT 4.13
<TEXT>
Document 3 - file: tm2032415d4_ex4-13.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-4.14
<SEQUENCE>4
<FILENAME>tm2032415d4_ex4-14.htm
<DESCRIPTION>EXHIBIT 4.14
<TEXT>
Document 4 - file: tm2032415d4_ex4-14.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-5.1
<SEQUENCE>5
<FILENAME>tm2032415d4_ex5-1.htm
<DESCRIPTION>EXHIBIT 5.1
<TEXT>
Document 5 - file: tm2032415d4_ex5-1.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-10.24
<SEQUENCE>6
<FILENAME>tm2032415d4_ex10-24.htm
<DESCRIPTION>EXHIBIT 10.24
<TEXT>
Document 6 - file: tm2032415d4_ex10-24.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.1
<SEQUENCE>7
<FILENAME>tm2032415d4_ex23-1.htm
<DESCRIPTION>EXHIBIT 23.1
<TEXT>
Document 7 - file: tm2032415d4_ex23-1.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>8
<FILENAME>lg_invivotherape-4clr.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 8 - file: lg_invivotherape-4clr.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>9
<FILENAME>lg_invivotherapetm-4clr.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 9 - file: lg_invivotherapetm-4clr.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>10
<FILENAME>tm2032415d4_ex5-1img01.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 10 - file: tm2032415d4_ex5-1img01.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>11
<FILENAME>tm2032415d4_ex5-1img02.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 11 - file: tm2032415d4_ex5-1img02.jpg

</DOCUMENT>
</SEC-DOCUMENT>