<SEC-DOCUMENT>0001047469-16-011119-index.html : 20160314
<SEC-HEADER>0001047469-16-011119.hdr.sgml : 20160314
<ACCEPTANCE-DATETIME>20160314170000
ACCESSION NUMBER:		0001047469-16-011119
CONFORMED SUBMISSION TYPE:	424B5
PUBLIC DOCUMENT COUNT:		4
FILED AS OF DATE:		20160314
DATE AS OF CHANGE:		20160314

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			INVIVO THERAPEUTICS HOLDINGS CORP.
		CENTRAL INDEX KEY:			0001292519
		STANDARD INDUSTRIAL CLASSIFICATION:	SURGICAL & MEDICAL INSTRUMENTS & APPARATUS [3841]
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			NV
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		424B5
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-188573
		FILM NUMBER:		161504536

	BUSINESS ADDRESS:	
		STREET 1:		ONE KENDALL SQUARE
		STREET 2:		BUILDING 1400 EAST 4TH FLOOR
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02139
		BUSINESS PHONE:		617-863-5524

	MAIL ADDRESS:	
		STREET 1:		ONE KENDALL SQUARE
		STREET 2:		BUILDING 1400 EAST 4TH FLOOR
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02139

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Design Source, Inc.
		DATE OF NAME CHANGE:	20040602
</SEC-HEADER>
<DOCUMENT>
<TYPE>424B5
<SEQUENCE>1
<FILENAME>a2227745z424b5.htm
<DESCRIPTION>424B5
<TEXT>
Document 1 - file: a2227745z424b5.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>2
<FILENAME>g861990.jpg
<DESCRIPTION>G861990.JPG
<TEXT>
Document 2 - file: g861990.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>3
<FILENAME>g186823.jpg
<DESCRIPTION>G186823.JPG
<TEXT>
Document 3 - file: g186823.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>4
<FILENAME>g155029.jpg
<DESCRIPTION>G155029.JPG
<TEXT>
Document 4 - file: g155029.jpg

</DOCUMENT>
</SEC-DOCUMENT>