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Consolidated Statements of Cash Flows (USD $)
12 Months Ended 97 Months Ended
Dec. 31, 2013
Dec. 31, 2012
Dec. 31, 2011
Dec. 31, 2013
Cash flows from operating activities:        
Net income (loss) $ (38,755,922) $ 4,663,681 $ (34,728,215) $ (81,909,055)
Adjustments to reconcile net income (loss) to net cash used in operating activities:        
Depreciation and amortization expense 740,692 366,893 144,662 1,345,212
Non-cash derivative (gain) losses 18,871,329 (17,479,674) 26,065,579 31,409,816
Non-cash interest expense   21,870   984,704
Non-cash loss from modification of warrants 764,769     764,769
Common stock issued to 401(k) plan 191,802 91,524 41,662 324,988
Common stock issued for services   24,750 209,451 234,201
Share-based compensation expense 3,135,646 1,232,959 921,512 6,168,957
Changes in operating assets and liabilities:        
Restricted cash (120) (53,468) (547,883) (601,471)
Prepaid expenses and other current assets 123,780 (60,575) (12,805) (30,766)
Other assets 4,560   (125,000) (195,440)
Accounts payable (253,290) 585,355 230,250 899,260
Accrued interest payable       (15,256)
Accrued expenses 270,910 402,906 370,822 1,292,185
Net cash used in operating activities (14,905,844) (10,203,779) (7,429,965) (39,327,896)
Cash flows from investing activities:        
Purchases of property and equipment (748,460) (2,140,853) (278,923) (3,520,021)
Net cash used in investing activities (748,460) (2,140,853) (278,923) (3,520,021)
Cash flows from financing activities:        
Proceeds from issuance of note payable 149,768     149,768
Repayment of note payable (57,284)     (57,284)
Proceeds from issuance of convertible notes payable       4,181,000
Proceeds from convertible bridge notes       500,000
Principal payments on capital lease obligation (32,606) (33,361) (24,774) (90,741)
Proceeds from loans payable 342,000 1,747,000 151,733 2,240,733
Repayment of loans payable   (303,372) (17,361) (320,733)
Proceeds from issuance of common stock and warrants 16,407,657 19,395,743 2,998,808 50,225,495
Net cash provided by financing activities 16,809,535 20,806,010 3,108,406 56,828,238
Increase (Decrease) in cash and cash equivalents 1,155,231 8,461,378 (4,600,482) 13,980,321
Cash and cash equivalents at beginning of period 12,825,090 4,363,712 8,964,194  
Cash and cash equivalents at end of period 13,980,321 12,825,090 4,363,712 13,980,321
Supplemental disclosure of cash flow information and non-cash transactions:        
Cash paid for interest 125,342 49,862 8,530 281,251
Conversion of convertible notes payable and accrued interest into common stock       4,672,484
Conversion of convertible bridge note payable and accrued interest into common stock       504,597
Asset acquired through capital lease obligation     93,540 93,540
Beneficial conversion feature on convertible and bridge notes payable       134,410
Fair value of warrants issued with bridge notes payable       178,726
Fair value of warrants issued in connection with loan agreement   31,916 10,051 41,967
Issuance of founders shares       248
Reclassification of derivative warrant liability to additional paid-in capital $ 33,456,147 $ 3,408,738 $ 1,239,539 $ 38,104,424