X0306 4 2022-02-11 false 0001597553 Sage Therapeutics, Inc. SAGE 0001291963 Greene Barry E C/O SAGE THERAPEUTICS, INC. 215 FIRST STREET CAMBRIDGE MA 02142 true true false false President and CEO Stock Option (Right to Buy) 43.04 2022-02-11 4 A false 69920.00 0.00 A 2032-02-11 Common Stock 69920.00 69920.00 D The securities awarded on February 11, 2022 were in the form of stock options issued pursuant to the Sage Therapeutics, Inc. 2014 Stock Option and Incentive Plan. Options to purchase 17,480 shares of common stock shall vest on the one year anniversary of February 11, 2022, with 52,440 shares vesting in 36 equal monthly installments thereafter. /s/ Jennifer Fitzpatrick, as Attorney-in-Fact for Barry Greene 2022-02-15