X0306 4 2014-06-04 0 0001059790 POZEN INC /NC POZN 0001290976 Kirsch Arthur S C/O POZEN INC. 1414 RALEIGH ROAD, SUITE 400 CHAPEL HILL NC 27517 1 0 0 0 Common Stock 2014-06-04 4 A 0 9291 0.00 A 40291 D Common Stock 2014-06-05 4 M 0 2500 5.78 A 42791 D Common Stock 2014-06-05 4 S 0 2500 8.668 D 40291 D Stock Option 5.78 2014-06-05 4 M 0 2500 0.00 D 2015-01-03 Common Stock 2500 9430 D Restricted Stock Units, all of which vest on the earlier of 6/4/2015 or the date of the Company's next annual shareholder meeting. Includes 31,000 shares of Common Stock and 9,291 Restricted Stock Units. The price in column 4 is a weighted average price. The prices actually received by the reporting person in this transaction range from $8.664 to $8.67. The reporting person has provided to the issuer, and the issuer will provide to any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range reported. The options vested in four equal annual installments, with the initial vesting date occurring on January 3, 2006. /s/ John E. Barnhardt, attorney-in-fact 2014-06-06