X0306 4 2019-07-25 0 0001609550 Inspire Medical Systems, Inc. INSP 0001290170 Ellis Gary Lee C/O INSPIRE MEDICAL SYSTEMS, INC. 5500 WAYZATA BLVD., SUITE 1600 GOLDEN VALLEY MN 55416 1 0 0 0 Stock Option (right to buy) 67.75 2019-07-25 4 A 0 5261 0 A 2029-07-25 Common Stock 5261 5261 D The option vests and becomes exercisable in three equal annual installments beginning on July 25, 2020, subject to the Reporting Person's continuous service to the Issuer through the applicable vesting date. /s/ Richard Buchholz, as Attorney-in-Fact for Gary L. Ellis 2019-07-29