The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
21VIANET GROUP INC SPONSORED ADR 90138A103 10,488 525,189 SH   DFND   525,189 0 0
ACCELERON PHARMA INC COM 00434H108 18,537 702,410 SH   DFND   702,410 0 0
ADAPTIMMUNE THERAPEUTICS PLC SPONDS ADR 00653A107 6,371 783,645 SH   DFND   783,645 0 0
AGENUS INC COM NEW 00847G705 16,129 3,877,072 SH   DFND   3,877,072 0 0
AKARI THERAPEUTICS PLC SPONSORED ADR 00972G108 3,205 263,921 SH   DFND   263,921 0 0
ALERE INC COM 01449J105 5,083 100,442 SH   DFND   100,442 0 0
ARRAY BIOPHARMA INC NOTE 3.000% 6/0 04269XAA3 3,685 4,600,000 PRN   DFND   4,600,000 0 0
ARROWHEAD RESH CORP COM NEW 042797209 9,870 2,047,782 SH   DFND   2,047,782 0 0
ASSEMBLY BIOSCIENCES INC COM 045396108 3,049 740,700 SH   DFND   740,700 0 0
AVEXIS INC COM 05366U100 6,224 242,756 SH   DFND   242,756 0 0
BEIGENE LTD SPONSORED ADR 07725L102 4,983 170,000 SH   DFND   170,000 0 0
BELLICUM PHARMACEUTICALS INC COM 079481107 4,749 507,939 SH   DFND   507,939 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 8,767 106,289 SH   DFND   106,289 0 0
BLACKROCK INC COM 09247X101 20,434 60,000 SH Put DFND   60,000 0 0
BLUEBIRD BIO INC COM 09609G100 2,508 59,002 SH   DFND   59,002 0 0
BRF SA SPONSORED ADR 10552T107 8,633 607,112 SH   DFND   607,112 0 0
CHINA ZENIX AUTO INTL LTD ADS 16951E104 5,435 6,074,805 SH   DFND   6,074,805 0 0
CLOVIS ONCOLOGY INC NOTE 2.500% 9/1 189464AB6 29,665 43,295,000 PRN   DFND   43,295,000 0 0
CTRIP COM INTL LTD NOTE 1.250%10/1 22943FAD2 32,278 25,000,000 PRN   DFND   25,000,000 0 0
CYTRX CORP COM PAR $.001 232828509 14,905 5,850,399 SH   DFND   5,850,399 0 0
DHT HOLDINGS INC SHS NEW Y2065G121 2,653 460,522 SH   DFND   460,522 0 0
DHT HOLDINGS INC DEBT 4.500%10/0 23335SAB2 16,414 17,000,000 PRN   DFND   17,000,000 0 0
E HOUSE CHINA HLDGS LTD ADR 26852W103 2,590 416,438 SH   DFND   416,438 0 0
EPIZYME INC COM 29428V104 14,317 1,181,244 SH   DFND   1,181,244 0 0
EQUITY COMWLTH COM SH BEN INT 294628102 22,576 800,000 SH   DFND   800,000 0 0
FIBROCELL SCIENCE INC COM NEW 315721209 4,400 1,913,662 SH   DFND   1,913,662 0 0
FIVE PRIME THERAPEUTICS INC COM 33830X104 6,915 170,199 SH   DFND   170,199 0 0
GOLAR LNG LTD BERMUDA SHS G9456A100 5,396 300,283 SH   DFND   300,283 0 0
GOLDMAN SACHS GROUP INC COM 38141G104 79,174 504,356 SH   DFND   504,356 0 0
HALOZYME THERAPEUTICS INC COM 40637H109 6,576 694,436 SH   DFND   694,436 0 0
IKANG HEALTHCARE GROUP INC SPONSORED ADR 45174L108 21,111 965,717 SH   DFND   965,717 0 0
INTEL CORP COM 458140100 39,473 1,220,176 SH   DFND   1,220,176 0 0
INTEL CORP SDCV 12/1 458140AD2 40,958 31,920,000 PRN   DFND   31,920,000 0 0
INTERCEPT PHARMACEUTICALS IN COM 45845P108 10,283 80,044 SH   DFND   80,044 0 0
ISHARES TR NASDQ BIOTEC ETF 464287556 15,691 60,164 SH   DFND   60,164 0 0
ISHARES TR U.S. PFD STK ETF 464288687 32,005 820,000 SH Put DFND   820,000 0 0
JPMORGAN CHASE & CO COM 46625H100 13,436 226,879 SH   DFND   226,879 0 0
KKR & CO L P DEL COM UNITS 48248M102 8,287 564,149 SH   DFND   564,149 0 0
LION BIOTECHNOLOGIES INC COM 53619R102 8,119 1,598,309 SH   DFND   1,598,309 0 0
MAKEMYTRIP LIMITED MAURITIUS SHS V5633W109 35,041 2,034,024 SH   DFND   2,034,024 0 0
MARVELL TECHNOLOGY GROUP LTD ORD G5876H105 40,448 3,923,182 SH   DFND   3,923,182 0 0
MEDGENICS INC COM NEW 58436Q203 3,817 867,608 SH   DFND   867,608 0 0
MGIC INVT CORP WIS COM 552848103 1,342 175,000 SH   DFND   175,000 0 0
MICROCHIP TECHNOLOGY INC SDCV 2.125%12/1 595017AB0 31,435 15,764,000 PRN   DFND   15,764,000 0 0
MIRATI THERAPEUTICS INC COM 60468T105 11,955 558,625 SH   DFND   558,625 0 0
NAVIGATOR HOLDINGS LTD SHS Y62132108 10,510 650,769 SH   DFND   650,769 0 0
NEW YORK TIMES CO CL A 650111107 29,006 2,327,896 SH   DFND   2,327,896 0 0
NORDIC AMERICAN TANKERS LIMI COM G65773106 15,937 1,131,120 SH   DFND   1,131,120 0 0
NORDIC AMERICAN TANKERS LIMI COM G65773106 26,947 1,912,500 SH Put DFND   1,912,500 0 0
NORTHSTAR REALTY EUROPE CORP COM 66706L101 26,689 2,300,786 SH   DFND   2,300,786 0 0
OCERA THERAPEUTICS INC COM 67552A108 2,447 932,086 SH   DFND   932,086 0 0
OCWEN FINL CORP COM NEW 675746309 741 300,000 SH   DFND   300,000 0 0
PALATIN TECHNOLOGIES INC COM PAR $ .01 696077403 1,883 4,982,174 SH   DFND   4,982,174 0 0
PDVWIRELESS INC COM 69290R104 26,802 876,699 SH   DFND   876,699 0 0
PRONAI THERAPEUTICS INC COM 74346L101 472 70,000 SH   DFND   70,000 0 0
QIHOO 360 TECHNOLOGY CO LTD ADS 74734M109 40,121 531,047 SH   DFND   531,047 0 0
QIMONDA FIN LLC NOTE 6.750% 3/2 74732WAA7 12,872 82,885,000 PRN   DFND   82,885,000 0 0
REALOGY HLDGS CORP COM 75605Y106 14,444 400,000 SH   DFND   400,000 0 0
REGENXBIO INC COM 75901B107 4,527 424,368 SH   DFND   424,368 0 0
ROYAL BK CDA MONTREAL QUE COM 780087102 8,634 150,000 SH Put DFND   150,000 0 0
SAREPTA THERAPEUTICS INC COM 803607100 8,775 449,526 SH   DFND   449,526 0 0
SHIP FINANCE INTERNATIONAL L NOTE 3.250% 2/0 G81075AE6 37,258 38,000,000 PRN   DFND   38,000,000 0 0
SOLARCITY CORP COM 83416T100 10,000 406,816 SH   DFND   406,816 0 0
SOLARCITY CORP COM 83416T100 9,979 406,000 SH Put DFND   406,000 0 0
SPDR SERIES TRUST S&P BIOTECH 78464A870 289,296 5,600,000 SH Put DFND   5,600,000 0 0
TAIWAN SEMICONDUCTOR MFG LTD SPONSORED ADR 874039100 10,480 400,000 SH Put DFND   400,000 0 0
TAL ED GROUP NOTE 2.500% 5/1 874080AB0 46,707 24,000,000 PRN   DFND   24,000,000 0 0
TEEKAY TANKERS LTD CL A Y8565N102 6,684 1,821,389 SH   DFND   1,821,389 0 0
TENET HEALTHCARE CORP COM NEW 88033G407 23,312 805,823 SH   DFND   805,823 0 0
TRACON PHARMACEUTICALS INC COM 89237H100 2,306 363,292 SH   DFND   363,292 0 0
VERISIGN INC SDCV 3.250% 8/1 92343EAD4 103,695 40,000,000 PRN   DFND   40,000,000 0 0
VIPSHOP HLDGS LTD NOTE 1.500% 3/1 92763WAA1 17,595 17,500,000 PRN   DFND   17,500,000 0 0
WAYFAIR INC CL A 94419L101 8,644 200,000 SH   DFND   200,000 0 0
WAYFAIR INC CL A 94419L101 8,644 200,000 SH Put DFND   200,000 0 0
WELLS FARGO & CO NEW COM 949746101 24,864 514,153 SH   DFND   514,153 0 0
WESCO INTL INC DBCV 6.000% 9/1 95082PAH8 36,151 18,750,000 PRN   DFND   18,750,000 0 0
WL ROSS HLDG CORP COM SHS 92939D104 10,030 1,000,000 SH   DFND   1,000,000 0 0
XENCOR INC COM 98401F105 5,193 386,925 SH   DFND   386,925 0 0
XILINX INC COM 983919101 11,234 236,855 SH   DFND   236,855 0 0
YOUKU TUDOU INC SPONSORED ADR 98742U100 22,143 805,499 SH   DFND   805,499 0 0
YY INC NOTE 2.250% 4/0 98426TAB2 4,875 5,000,000 PRN   DFND   5,000,000 0 0
ZILLOW GROUP INC CL C CAP STK 98954M200 11,034 465,000 SH   DFND   465,000 0 0
ZILLOW GROUP INC CL A 98954M101 8,942 350,000 SH   DFND   350,000 0 0
ZILLOW GROUP INC CL C CAP STK 98954M200 1,424 60,000 SH Put DFND   60,000 0 0