The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACCELERON PHARMA INC COM 00434H108 28,989 761,661 SH   DFND   761,661 0 0
AGENUS INC COM NEW 00847G705 18,791 3,662,932 SH   DFND   3,662,932 0 0
ALTISOURCE PORTFOLIO SOLNS S REG SHS L0175J104 7,928 616,031 SH   DFND   616,031 0 0
ALTISOURCE RESIDENTIAL CORP CL B 02153W100 4,172 200,000 SH Put DFND   200,000 0 0
ALTISOURCE RESIDENTIAL CORP CL B 02153W100 6,038 289,455 SH   DFND   289,455 0 0
ANACOR PHARMACEUTICALS INC COM 032420101 16,452 284,383 SH   DFND   284,383 0 0
ARMSTRONG WORLD INDS INC NEW COM 04247X102 3,782 65,800 SH   DFND   65,800 0 0
ARRAY BIOPHARMA INC NOTE 3.000% 6/0 04269XAA3 11,406 9,000,000 PRN   DFND   9,000,000 0 0
ARROWHEAD RESH CORP COM NEW 042797209 14,158 2,101,510 SH   DFND   2,101,510 0 0
ASSEMBLY BIOSCIENCES INC COM 045396108 7,083 535,000 SH   DFND   535,000 0 0
AVALANCHE BIOTECHNOLOGIES IN COM 05337G107 3,694 91,154 SH   DFND   91,154 0 0
BIOCRYST PHARMACEUTICALS COM 09058V103 11,824 1,309,382 SH   DFND   1,309,382 0 0
BLUEBIRD BIO INC COM 09609G100 14,232 117,844 SH   DFND   117,844 0 0
BRF SA SPONSORED ADR 10552T107 13,225 668,626 SH   DFND   668,626 0 0
CANADIAN SOLAR INC COM 136635109 16,695 500,000 SH Put DFND   500,000 0 0
CAPITAL ONE FINL CORP COM 14040H105 21,425 271,824 SH   DFND   271,824 0 0
CHINA ZENIX AUTO INTL LTD ADS 16951E104 5,624 6,074,805 SH   DFND   6,074,805 0 0
CITIZENS FINL GROUP INC COM 174610105 14,961 620,000 SH   DFND   620,000 0 0
CONCERT PHARMACEUTICALS INC COM 206022105 3,938 259,999 SH   DFND   259,999 0 0
CTRIP COM INTL LTD AMERICAN DEP SHS 22943F100 21,815 372,146 SH   DFND   372,146 0 0
CTRIP COM INTL LTD NOTE 1.250%10/1 22943FAD2 15,780 15,000,000 PRN   DFND   15,000,000 0 0
CYTRX CORP COM PAR $.001 232828509 17,777 5,275,188 SH   DFND   5,275,188 0 0
DHT HOLDINGS INC DEBT 4.500%10/0 23335SAB2 18,233 17,000,000 PRN   DFND   17,000,000 0 0
DYAX CORP COM 26746E103 10,017 597,866 SH   DFND   597,866 0 0
EBAY INC COM 278642103 46,366 803,852 SH   DFND   803,852 0 0
EBAY INC COM 278642103 3,576 62,000 SH Call DFND   62,000 0 0
ELECTRONIC ARTS INC NOTE 0.750% 7/1 285512AA7 4,639 2,500,000 PRN   DFND   2,500,000 0 0
ELONG INC SPONSORED ADR 290138205 7,500 523,300 SH   DFND   523,300 0 0
ENDO HEALTH SOLUTIONS INC NOTE 1.750% 4/1 29264FAB2 30,644 10,000,000 PRN   DFND   10,000,000 0 0
EPIZYME INC COM 29428V104 15,606 831,000 SH   DFND   831,000 0 0
EURONAV NV ANTWERPEN SHS TEMP B38564124 7,313 606,349 SH   DFND   606,349 0 0
FIRST SOLAR INC COM 336433107 5,979 100,000 SH Put DFND   100,000 0 0
FIVE PRIME THERAPEUTICS INC COM 33830X104 9,288 406,457 SH   DFND   406,457 0 0
GREEN DOT CORP CL A 39304D102 14,885 934,997 SH   DFND   934,997 0 0
HALOZYME THERAPEUTICS INC COM 40637H109 12,157 851,305 SH   DFND   851,305 0 0
HOME LN SERVICING SOLUTIONS ORD SHS G6648D109 5,278 319,100 SH Put DFND   319,100 0 0
HOME LN SERVICING SOLUTIONS ORD SHS G6648D109 7,569 457,638 SH   DFND   457,638 0 0
INTEL CORP COM 458140100 3,671 117,400 SH   DFND   117,400 0 0
INTERCEPT PHARMACEUTICALS IN COM 45845P108 1,199 4,251 SH   DFND   4,251 0 0
ISHARES US HOME CONS ETF 464288752 12,907 457,214 SH   DFND   457,214 0 0
JD COM INC SPON ADR CL A 47215P106 30,823 1,049,100 SH   DFND   1,049,100 0 0
LION BIOTECHNOLOGIES INC COM 53619R102 16,046 1,325,000 SH   DFND   1,325,000 0 0
LOWES COS INC COM 548661107 7,725 103,850 SH   DFND   103,850 0 0
LUMBER LIQUIDATORS HLDGS INC COM 55003T107 17,479 567,882 SH   DFND   567,882 0 0
LUMBER LIQUIDATORS HLDGS INC COM 55003T107 64,798 2,105,200 SH Put DFND   2,105,200 0 0
MAKEMYTRIP LIMITED MAURITIUS SHS V5633W109 31,950 1,454,913 SH   DFND   1,454,913 0 0
MEDIVATION INC COM 58501N101 4,868 37,714 SH   DFND   37,714 0 0
MGIC INVT CORP WIS COM 552848103 11,804 1,225,716 SH   DFND   1,225,716 0 0
MGM RESORTS INTERNATIONAL COM 552953101 14,418 685,600 SH   DFND   685,600 0 0
MICROCHIP TECHNOLOGY INC SDCV 2.125%12/1 595017AB0 27,995 14,264,000 PRN   DFND   14,264,000 0 0
MIRATI THERAPEUTICS INC COM 60468T105 13,384 456,466 SH   DFND   456,466 0 0
MOL GLOBAL INC SPONSORED ADR 60845Q105 3,868 1,689,290 SH   DFND   1,689,290 0 0
NAVIGATOR HOLDINGS LTD SHS Y62132108 23,117 1,210,300 SH   DFND   1,210,300 0 0
NORTHSTAR ASSET MGMT GROUP I COM 66705Y104 5,778 247,572 SH   DFND   247,572 0 0
NORTHSTAR RLTY FIN CORP COM NEW 66704R704 18,337 1,012,000 SH   DFND   1,012,000 0 0
NOVELLUS SYS INC NOTE 2.625% 5/1 670008AD3 69,518 33,742,000 PRN   DFND   33,742,000 0 0
OCERA THERAPEUTICS INC COM 67552A108 2,779 590,127 SH   DFND   590,127 0 0
OCWEN FINL CORP COM NEW 675746309 15,088 1,828,800 SH Put DFND   1,828,800 0 0
OCWEN FINL CORP COM NEW 675746309 25,707 3,115,983 SH   DFND   3,115,983 0 0
ONCOTHYREON INC COM 682324108 7,044 4,321,764 SH   DFND   4,321,764 0 0
PACIFIC DATAVISION INC COM 694171307 32,559 754,916 SH   DFND   754,916 0 0
PALATIN TECHNOLOGIES INC COM PAR $ .01 696077403 3,157 3,495,336 SH   DFND   3,495,336 0 0
REALOGY HLDGS CORP COM 75605Y106 19,749 434,240 SH   DFND   434,240 0 0
RETROPHIN INC COM 761299106 7,403 308,989 SH   DFND   308,989 0 0
SELECT SECTOR SPDR TR SBI INT-ENERGY 81369Y506 11,650 150,174 SH   DFND   150,174 0 0
SOLARCITY CORP COM 83416T100 17,354 338,416 SH   DFND   338,416 0 0
SOLARCITY CORP COM 83416T100 31,076 606,000 SH Put DFND   606,000 0 0
SPARK THERAPEUTICS INC COM 84652J103 581 7,500 SH   DFND   7,500 0 0
SPDR SERIES TRUST S&P BIOTECH 78464A870 293,150 1,300,000 SH Put DFND   1,300,000 0 0
TEKMIRA PHARMACEUTICALS CORP COM NEW 87911B209 279,596 16,013,540 SH   DFND   0 16,013,540 0
TENET HEALTHCARE CORP COM NEW 88033G407 27,086 547,085 SH   DFND   547,085 0 0
TRACON PHARMACEUTICALS INC COM 89237H100 5,001 368,330 SH   DFND   368,330 0 0
TRINA SOLAR LIMITED SPON ADR 89628E104 1,264 104,519 SH   DFND   104,519 0 0
UNITED THERAPEUTICS CORP DEL NOTE 1.000% 9/1 91307CAF9 81,122 22,500,000 PRN   DFND   22,500,000 0 0
VIPSHOP HLDGS LTD NOTE 1.500% 3/1 92763WAA1 10,928 7,000,000 PRN   DFND   7,000,000 0 0
WALTER ENERGY INC COM 93317Q105 31 49,300 SH   DFND   49,300 0 0
WESCO INTL INC DBCV 6.000% 9/1 95082PAH8 46,979 19,000,000 PRN   DFND   19,000,000 0 0
WL ROSS HLDG CORP COM SHS 92939D104 10,000 1,000,000 SH   DFND   1,000,000 0 0
XENCOR INC COM 98401F105 8,272 539,960 SH   DFND   539,960 0 0