Stockholders' Equity - Additional Information (Detail) - USD ($)		1 Months Ended			3 Months Ended		12 Months Ended
	Feb. 03, 2022	Jan. 31, 2022	Jan. 31, 2020	Aug. 31, 2018	Mar. 31, 2022	Mar. 31, 2021	Dec. 31, 2021	Nov. 30, 2021	Nov. 30, 2019
Class Of Stock [Line Items]
Proceeds from warrant exercises					$ 40,346,000	$ 660,000
Expense relating to the modifications to warrants							$ 0
Silicon Valley Bank [Member] | Term Loans [Member] | Warrants [Member]
Class Of Stock [Line Items]
Exercise price of warrants or rights				$ 74.80
Warrant expiration date				Aug. 21, 2028
Warrants issued in connection with loan				1,839
Asset Purchase Agreement Amendment [Member] | Gilead [Member]
Class Of Stock [Line Items]
Issuance of common stock, Shares			725,283
Number of securities called by warrants and rights			725,283
Exercise price of warrants or rights			$ 13.20
Issuance of common stock for exercise of common stock warrant, Shares					725,283
Proceeds from warrant exercises					$ 9,600,000
Series A Warrants [Member]
Class Of Stock [Line Items]
Number of securities called by warrants and rights									7,802,241
Exercise price of warrants or rights									$ 13.20
Warrant expiration date					Jan. 22, 2025
Issuance of common stock for exercise of common stock warrant, Shares					18,937
Proceeds from warrant exercises					$ 200,000
Series B Warrants [Member]
Class Of Stock [Line Items]
Number of securities called by warrants and rights									2,574,727
Exercise price of warrants or rights									$ 13.20
Issuance of common stock for exercise of common stock warrant, Shares					2,312,257	49,995
Proceeds from warrant exercises					$ 30,500,000	$ 700,000
Common Stock [Member]
Class Of Stock [Line Items]
Issuance of common stock, Shares					4,824,075	1,149,820
Issuance of common stock for exercise of common stock warrant, Shares					3,056,477	49,995
Underwritten Public Offering [Member]
Class Of Stock [Line Items]
Proceeds from issuance of common stock, net of deferred financing costs		$ 145,300,000
Underwriting discounts and commissions and offering expenses		$ 9,900,000
Underwritten Public Offering [Member] | Common Stock [Member]
Class Of Stock [Line Items]
Issuance of common stock, Shares	750,000	4,074,075
Share issued price per share		$ 27.00
Underwritten Public Offering [Member] | Warrants [Member]
Class Of Stock [Line Items]
Number of securities called by warrants and rights		925,925
Share issued price per share		$ 26.999
At-The-Market Offering [Member]
Class Of Stock [Line Items]
Issuance of common stock, Shares					0	1,149,820
Proceeds from issuance of common stock, net of offering costs						$ 19,600,000
Authorized stock issuance value remaining capacity					$ 59,600,000
At-The-Market Offering [Member] | Maximum [Member]
Class Of Stock [Line Items]
Common stock reserved for issuance								$ 150,000,000.0