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Organization - Additional Information (Detail) - USD ($)
$ / shares in Units, $ in Thousands
Apr. 12, 2022
Mar. 31, 2022
Dec. 31, 2021
Mar. 31, 2021
Organization [Line Items]        
Cash and cash equivalents   $ 274,015 $ 104,749 $ 107,658
GlaxoSmithKline [Member] | Subsequent Event [Member]        
Organization [Line Items]        
Right to receive cash without interest per share $ 55.00      
Termination fee $ 70,000