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Stock-Based Compensation - Summary of Stock-Based Compensation Activity (Detail) - 2008 Plan, 2015 Plan and 2018 Plan [Member] - USD ($)
$ / shares in Units, $ in Thousands
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Options Outstanding, Shares Available for Grant    
Shares Available for Grant, Beginning balance 1,117,796  
Shares Available for Grant, Awards authorized 945,139  
Shares Available for Grant, Granted (1,134,860)  
Shares Available for Grant, forfeited/cancelled 279,752  
Shares Available for Grant, Ending balance 1,207,827 1,117,796
Options Outstanding, Number of Shares Outstanding    
Number of Shares Outstanding, Beginning balance 4,146,928  
Number of Shares Outstanding, Options granted 1,134,860  
Number of Shares Outstanding, Options exercised (64,847) 0
Number of Shares Outstanding, Options forfeited/cancelled (279,752)  
Number of Shares Outstanding, Ending balance 4,937,189 4,146,928
Number of Shares Outstanding, Exercisable 1,421,885  
Number of Shares Outstanding, Vested and expected to vest 4,422,699  
Options Outstanding, Weighted-Average Exercise Price Per Share    
Weighted-Average Exercise Price Per Share, Beginning balance $ 19.45  
Weighted-Average Exercise Price Per Share, Options granted 17.78  
Weighted-Average Exercise Price Per Share, Options exercised 13.06  
Weighted-Average Exercise Price Per Share, Options forfeited/cancelled 17.99  
Weighted-Average Exercise Price Per Share, Ending balance 19.23 $ 19.45
Weighted-Average Exercise Price Per Share, Exercisable 30.98  
Weighted-Average Exercise Price Per Share, Vested and expected to vest $ 20.06  
Options Outstanding, Weighted-Average Remaining Contractual Term (Years)    
Weighted-Average Remaining Contractual Term (Years) 8 years 1 month 20 days 8 years 10 months 2 days
Weighted-Average Remaining Contractual Term (Year), Exercisable 6 years 6 months 21 days  
Weighted-Average Remaining Contractual Term (Year), Vested and expected to vest 8 years 25 days  
Options Outstanding, Aggregate Intrinsic Value of Outstanding Options    
Aggregate Intrinsic Value of Outstanding Options $ 36,080 $ 12,227
Aggregate Intrinsic Value of Outstanding Options, Exercisable 9,682  
Aggregate Intrinsic Value of Outstanding Options, Vested and expected to vest $ 31,146