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Net Loss Per Share - Schedule of Outstanding Shares of Common Stock Equivalents Excluded from Calculation of Diluted Net Loss Per Share (Detail) - shares
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Total potential dilutive shares 15,979,922 15,251,018 10,704,830
Series A Warrants For Common Stock [Member]      
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Total potential dilutive shares 7,790,879 7,802,241 7,802,241
Series B Warrants For Common Stock [Member]      
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Total potential dilutive shares 2,524,732 2,574,727 2,574,727
Options to Purchase Common Stock [Member]      
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Total potential dilutive shares 4,937,189 4,146,928 326,023
Warrants for Common Stock [Member]      
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Total potential dilutive shares 727,122 727,122 1,839