X0206 3 2015-07-15 0 0001290149 ProNAi Therapeutics Inc DNAI 0001297500 Pelzer Robert C/O PRONAI THERAPEUTICS, INC. 2150 ? 885 WEST GEORGIA ST. VANCOUVER A1 V6C 3E8 BRITISH COLUMBIA, CANADA 1 0 0 0 Stock Option (right to buy) 6.705 2025-06-17 Common Stock 26846 D The option vests as to 8.333% of the total shares monthly, beginning on July 18, 2015, with 100% of the total shares vested and exercisable on June 18, 2016, subject to the reporting person's provision of service to the issuer on each vesting date. /s/ Sukhi Jagpal as attorney-in-fact for Robert Pelzer 2015-07-15