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Stock-Based Compensation - Additional Information (Detail) - USD ($)
$ / shares in Units, $ in Millions
3 Months Ended
Jan. 21, 2020
Mar. 31, 2020
Mar. 31, 2019
Dec. 31, 2019
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Number of common stock shares reserved for issuance   15,886,314   18,577,117
Common shares authorized to be issued during the period 4,312,500      
2015 Plan [Member]        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Number of common stock shares reserved for issuance   4,678,379    
Stock option life in years   10 years    
Stock option grants description   The number of shares reserved for issuance under the 2015 Plan will increase automatically on January 1 of each calendar year 2016 through 2025 by the number of shares equal to 4% of the total outstanding shares of the Company’s common stock as of the immediately preceding December 31.    
Percentage threshold of outstanding shares increased annually under the plan   4.00%    
2008 Plan, 2015 Plan and 2018 Plan [Member]        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Weighted-average grant date fair values of options granted   $ 9.81 $ 58.80  
Aggregate intrinsic value of options exercised     $ 0.1  
Total grant date fair value of options vested   $ 1.6 $ 2.7  
Total unrecognized stock-based compensation related to unvested stock options   $ 18.9    
Weighted-average period   3 years 4 months 24 days    
Common shares authorized to be issued during the period   4,387,187    
2018 Equity Inducement Plan [Member]        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Number of common stock shares reserved for issuance   37,500