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Consolidated Statements of Operations and Comprehensive Loss - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Operating expenses:      
Research and development $ 53,249 $ 41,078 $ 30,157
General and administrative 13,743 14,339 12,462
Total operating expenses 66,992 55,417 42,619
Loss from operations (66,992) (55,417) (42,619)
Other income (expense), net:      
Changes in fair value of warrant liabilities (20,926)    
Other income (expense), net (517) 1,780 760
Total other income (expense) (21,443) 1,780 760
Loss before provision for (benefit from) income taxes, net (88,435) (53,637) (41,859)
Provision for (benefit from) income taxes, net (160) (302) 156
Net loss and comprehensive loss $ (88,275) $ (53,335) $ (42,015)
Net loss per common share, basic and diluted $ (30.30) $ (30.16) $ (33.68)
Weighted-average shares used in computing net loss per common share, basic and diluted 2,913,487 1,768,480 1,247,482