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Term Loan - Additional Information (Detail)
3 Months Ended
Aug. 21, 2018
USD ($)
Tranches
Mar. 31, 2019
USD ($)
$ / shares
shares
Mar. 31, 2018
USD ($)
Debt Instrument [Line Items]      
Amount borrowed   $ 5,000,000  
Silicon Valley Bank [Member] | Maximum [Member]      
Debt Instrument [Line Items]      
Number of common stock issuable | shares   220,588  
Silicon Valley Bank [Member] | Term Loans [Member]      
Debt Instrument [Line Items]      
Aggregate principal amount of loans $ 15,000,000    
Number of tranches | Tranches 3    
Loan agreement, description   Contemporaneously with executing the Loan Agreement, the Company drew down the first $5.0 million tranche. The second and third $5.0 million tranches may be drawn only upon the achievement of certain development milestones.  
Loan agreement, frequency of payments   Monthly  
Interest payment description   Borrowings under the Loan Agreement bear interest at the greater of (i) 6.0% or (ii) a floating per annum rate 1.0% above the prime rate (for an interest rate of 6.50% at March 31, 2019), with interest only due and payable monthly, until March 1, 2020, at which time interest and principal will be due and payable monthly in equal monthly payments; are subject to a final payment fee equal to 6.75% of the aggregate principal amount.  
Final payment fee as percent of aggregate principal amount of borrowing 6.75%    
Minimum requirement of cash and cash equivalents held with bank   $ 10,000,000  
Minimum percentage requirement of cash and cash equivalents held with bank   80.00%  
Applicable interest rate of loan   5.00%  
Loan payment fee   $ 300,000  
Interest expense   $ 100,000 $ 0
Silicon Valley Bank [Member] | Term Loans [Member] | Prime Rate [Member]      
Debt Instrument [Line Items]      
Loan agreement bear interest rate   6.50%  
Variable rate on borrowings above prime rate, percentage 1.00%    
Silicon Valley Bank [Member] | Term Loans [Member] | Minimum [Member]      
Debt Instrument [Line Items]      
Loan agreement bear interest rate 6.00%    
Silicon Valley Bank [Member] | Term Loans [Member] | Tranche One [Member]      
Debt Instrument [Line Items]      
Aggregate principal amount of loans $ 5,000,000    
Amount borrowed 5,000,000    
Effective interest rate of loan   9.89%  
Unamortized debt discount   $ 100,000  
Amortization of debt discount and accrual of final payment   $ 100,000  
Silicon Valley Bank [Member] | Term Loans [Member] | Tranche Two [Member]      
Debt Instrument [Line Items]      
Aggregate principal amount of loans 5,000,000    
Silicon Valley Bank [Member] | Term Loans [Member] | Tranche Three [Member]      
Debt Instrument [Line Items]      
Aggregate principal amount of loans $ 5,000,000    
Silicon Valley Bank [Member] | Warrants to Purchase Common Stock [Member]      
Debt Instrument [Line Items]      
Warrant expiration date   Aug. 21, 2028  
Silicon Valley Bank [Member] | Warrants to Purchase Common Stock [Member] | Term Loans [Member]      
Debt Instrument [Line Items]      
Warrants issued in connection with loan | shares   73,529  
Price per share of issued warrants | $ / shares   $ 1.87