Non cash restructuring charge.

No definition available.

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- Definition

Amount of cash payments made as the result of exit or disposal activities. Excludes payments associated with a discontinued operation or an asset retirement obligation.

+ References

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 420
-SubTopic 10
-Section 50
-Paragraph 1
-Subparagraph (b)(2)
-URI http://asc.fasb.org/extlink&oid=6394359&loc=d3e17939-110869

Reference 2: http://www.xbrl.org/2009/role/commonPracticeRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 230
-SubTopic 10
-Section 45
-Paragraph 17
-Subparagraph (f)
-URI http://asc.fasb.org/extlink&oid=109223946&loc=d3e3367-108585

+ Details

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Balance Type:	credit
Period Type:	duration

- Definition

Amount of expenses associated with exit or disposal activities pursuant to an authorized plan. Excludes expenses related to a discontinued operation or an asset retirement obligation.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 420
-SubTopic 10
-Section S99
-Paragraph 1
-Subparagraph (SAB Topic 5.P.3)
-URI http://asc.fasb.org/extlink&oid=115931487&loc=d3e140864-122747

Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 420
-SubTopic 10
-Section 50
-Paragraph 1
-Subparagraph (b)
-URI http://asc.fasb.org/extlink&oid=6394359&loc=d3e17939-110869

Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef
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-Topic 230
-SubTopic 10
-Section 45
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-URI http://asc.fasb.org/extlink&oid=109223946&loc=d3e3602-108585

Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 420
-SubTopic 10
-Section S99
-Paragraph 2
-Subparagraph (SAB Topic 5.P.4(b))
-URI http://asc.fasb.org/extlink&oid=115931487&loc=d3e140904-122747

+ Details

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Period Type:	duration

- Definition

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

+ References

No definition available.

+ Details

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Data Type:	xbrli:stringItemType
Balance Type:	na
Period Type:	duration

- Definition

Amount of expense (reversal of expense) which increases (decreases) the restructuring reserve from an adjustment to a previously accrued restructuring liability.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 420
-SubTopic 10
-Section 50
-Paragraph 1
-Subparagraph (b)
-URI http://asc.fasb.org/extlink&oid=6394359&loc=d3e17939-110869

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-URI http://asc.fasb.org/extlink&oid=115931487&loc=d3e140904-122747

+ Details

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Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	debit
Period Type:	duration

- Definition

Carrying amount as of the balance sheet date of known and estimated obligations associated with exit from or disposal of business activities or restructurings pursuant to a duly authorized plan, which are expected to be paid in the next twelve months or in the normal operating cycle if longer. Costs of such activities include those for one-time termination benefits, termination of an operating lease or other contract, consolidating or closing facilities, relocating employees, and costs associated with an ongoing benefit arrangement, but excludes costs associated with the retirement of a long-lived asset.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 420
-SubTopic 10
-Section 50
-Paragraph 1
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-URI http://asc.fasb.org/extlink&oid=115931487&loc=d3e140904-122747

+ Details

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Period Type:	instant

- Details

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- Details

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- Details

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- Details

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- Details

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Restructuring Costs - Summary of Restructuring Activities (Detail) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2018	Dec. 31, 2017	Dec. 31, 2016
Restructuring Cost and Reserve [Line Items]
Beginning balance	$ 137
Non-cash charges			$ (811)
Ending balance	33	$ 137
PNT2258 [Member]
Restructuring Cost and Reserve [Line Items]
Beginning balance	137	763
Adjustments to research and development expense	(99)	(69)
Non-cash charges			(811)
Cash payments	(5)	(557)	(1,142)
Ending balance	33	137	763
PNT2258 [Member] \| Contract Termination [Member]
Restructuring Cost and Reserve [Line Items]
Beginning balance	137	664
Adjustments to research and development expense	(99)	(69)
Non-cash charges			(681)
Cash payments	(5)	(458)	(909)
Ending balance	$ 33	137	664
PNT2258 [Member] \| Employee Termination [Member]
Restructuring Cost and Reserve [Line Items]
Beginning balance		99
Cash payments		$ (99)	(233)
Ending balance			99
PNT2258 [Member] \| Asset Impairment [Member]
Restructuring Cost and Reserve [Line Items]
Non-cash charges			(130)
Research and development [Member] \| PNT2258 [Member]
Restructuring Cost and Reserve [Line Items]
Restructuring cost			2,249
Research and development [Member] \| PNT2258 [Member] \| Contract Termination [Member]
Restructuring Cost and Reserve [Line Items]
Restructuring cost			2,249
General and administrative [Member] \| PNT2258 [Member]
Restructuring Cost and Reserve [Line Items]
Restructuring cost			467
General and administrative [Member] \| PNT2258 [Member] \| Contract Termination [Member]
Restructuring Cost and Reserve [Line Items]
Restructuring cost			5
General and administrative [Member] \| PNT2258 [Member] \| Employee Termination [Member]
Restructuring Cost and Reserve [Line Items]
Restructuring cost			332
General and administrative [Member] \| PNT2258 [Member] \| Asset Impairment [Member]
Restructuring Cost and Reserve [Line Items]
Restructuring cost			$ 130