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Stock-Based Compensation - Additional Information (Detail) - USD ($)
12 Months Ended
Jul. 15, 2015
Jul. 14, 2015
Dec. 31, 2018
Dec. 31, 2017
Dec. 31, 2016
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Expected dividend rate     0.00% 0.00% 0.00%
Number of common stock shares reserved for issuance     13,370,025 9,674,371  
Accounting Standards Update 2016-09 [Member]          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Retrospective adjustment to retained earnings     $ 8,000    
2015 Employee Stock Purchase Plan [Member]          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Number of common stock shares reserved for issuance 700,000   700,000 700,000  
Stock option grants description     The number of shares initially reserved for issuance under the ESPP will increase automatically on January 1 for nine years from the first offering date by the number of shares equal to 1% of the total outstanding shares of the Company’s common stock as of the immediately preceding December 31.    
Percentage threshold of outstanding shares increased annually under the plan 1.00%        
Common shares authorized to be issued during the period 3,400,000        
Options to purchase shares of common stock, discount percentage 15.00%        
Number of common stock issued     0    
2015 Plan [Member]          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Number of common stock shares reserved for issuance     8,637,065    
Stock option life in years     10 years    
Stock option grants description     The number of shares reserved for issuance under the 2015 Plan will increase automatically on January 1 of each calendar year from 2016 through 2025 by the number of shares equal to 4% of the total outstanding shares of the Company's common stock as of the immediately preceding December 31    
Percentage threshold of outstanding shares increased annually under the plan   4.00%      
Common shares authorized to be issued during the period     2,095,808    
2008 Plan, 2015 Plan and 2018 Plan [Member]          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Awards issued     3,566,150    
Awards outstanding     10,504,412 7,470,601  
Weighted-average grant date fair values of options granted     $ 1.75 $ 1.09 $ 2.19
Aggregate intrinsic value of options exercised     $ 200,000 $ 200,000 $ 1,200,000
Total grant date fair value of options vested     5,900,000 $ 6,500,000 $ 6,100,000
Total unrecognized stock-based compensation related to unvested stock options     $ 8,000,000    
Weighted-average period     2 years 1 month 6 days    
2018 Equity Inducement Plan [Member]          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Number of common stock shares reserved for issuance     1,500,000    
Stock option life in years     10 years    
Awards issued     0    
Awards outstanding     0    
Common shares authorized to be issued during the period     1,500,000