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Restructuring Costs
12 Months Ended
Dec. 31, 2017
Restructuring and Related Activities [Abstract]  
Restructuring Costs
12. Restructuring Costs

In June 2016, the Company halted investment in PNT2258 and the DNAi platform and closed the related Phase 2 clinical trials to further enrollment. As a result, the Company closed its research facility in Plymouth, Michigan, renegotiated and terminated certain contracts, and implemented staff reductions in the United States and Canada.

The following table summarizes restructuring activities for the years ended December 31, 2017 and December 31, 2016:

 

     Contract
Termination
    Employee
Termination
    Asset
Impairment
    Total  
     (in thousands)  

Accrual balance at December 31, 2015

   $ —       $ —       $ —       $ —    

Restructuring costs charged to research and development expense

     2,249       —         —         2,249  

Restructuring costs charged to general and administrative expense

     5       332       130       467  

Non-cash charges

     (681     —         (130     (811

Cash payments

     (909     (233     —         (1,142
  

 

 

   

 

 

   

 

 

   

 

 

 

Accrual balance at December 31, 2016

   $ 664     $ 99     $ —       $ 763  

Adjustments to research and development expense

     (69     —         —         (69

Cash payments

     (458     (99     —         (557
  

 

 

   

 

 

   

 

 

   

 

 

 

Accrual balance at December 31, 2017

   $ 137     $ —       $ —       $ 137  
  

 

 

   

 

 

   

 

 

   

 

 

 

The accrual balance, which was included in accrued liabilities in the accompanying balance sheet, is currently expected to be substantially paid by the end of 2018.