The selected consolidated quarterly financial results from operations for the years ended December 31, 2016 and 2015 are set forth therein. Net loss per share has been retroactively adjusted to reflect the 7.45-for-1 reverse stock split effected on June 29, 2015.


	Fiscal 2016 Quarter Ended
	March 31, 2016			June 30, 2016			September 30, 2016			December 31, 2016
	(in thousands, except per share amounts)
Operating expenses	$	10,613		$	12,946		$	15,283		$	9,233
Net loss	$	(10,538	)	$	(12,872	)	$	(15,209	)	$	(9,248	)
Net loss attributable to common stockholders	$	(10,538	)	$	(12,872	)	$	(15,209	)	$	(9,248	)
Basic and diluted net loss per share	$	(0.35	)	$	(0.43	)	$	(0.50	)	$	(0.30	)


	Fiscal 2015 Quarter Ended
	March 31, 2015			June 30, 2015			September 30, 2015			December 31, 2015
	(in thousands, except per share amounts)
Operating expenses	$	6,737		$	6,612		$	11,033		$	11,446
Net loss⁽¹⁾	$	(8,048	)	$	(15,249	)	$	(18,505	)	$	(11,458	)
Net loss attributable to common stockholders⁽¹⁾⁽²⁾	$	(19,053	)	$	(156,129	)	$	(266,544	)	$	(11,458	)
Basic and diluted net loss per share	$	(12.83	)	$	(104.10	)	$	(11.03	)	$	(0.38	)

(1)	Net loss for the quarters ended March 31, 2015, June 30, 2015 and September 30, 2015 included expenses related to changes in fair value of the preferred stock warrants of $1.3 million, $8.6 million and $7.5 million, respectively.

(2)

Net loss attributable to common stockholders for the quarters ended March 31, 2015, June 30, 2015 and September 30, 2015 included the impact of adjustment to redemption value on redeemable convertible preferred stock of $11.0 million, $140.9 million and $222.1 million, respectively. Net loss attributable to common stockholders for the quarter ended September 30, 2015 also included Series B and B-1 redeemable convertible preferred stock dividend of $5.5 million and Series C and D redeemable convertible preferred stock dividend of $20.4 million.