Selected Quarterly Financial Data (Tables)

12 Months Ended

Dec. 31, 2015

Quarterly Financial Information Disclosure [Abstract]

Summary of Selected Unaudited Consolidated Quarterly Financial Information

The Selected consolidated quarterly financial results from operations for the years ended December 31, 2015 and 2014 are set forth therein. Net loss per share for all periods presented has been retroactively adjusted to reflect the 7.45-for-1 reverse stock split effected on June 29, 2015.

	Fiscal 2015 Quarter Ended
	March 31, 2015			June 30, 2015			September 30, 2015			December 31, 2015
	(in thousands, except per share amounts)
Operating expenses	$	6,737		$	6,612		$	11,033		$	11,446
Net loss	$	(8,048	)	$	(15,249	)	$	(18,505	)	$	(11,458	)
Net loss attributable to common stockholders	$	(19,053	)	$	(156,129	)	$	(266,544	)	$	(11,458	)
Basic and diluted net loss per share	$	(12.83	)	$	(104.10	)	$	(11.03	)	$	(0.38	)

	Fiscal 2014 Quarter Ended
	March 31, 2014			June 30, 2014			September 30, 2014			December 31, 2014
	(in thousands, except per share amounts)
Operating expenses	$	2,320		$	13,508		$	3,480		$	3,270
Net loss	$	(2,467	)	$	(13,824	)	$	(3,961	)	$	(3,621	)
Net loss attributable to common stockholders	$	(4,909	)	$	(50,657	)	$	(9,552	)	$	(8,604	)
Basic and diluted net loss per share	$	(5.77	)	$	(55.04	)	$	(9.37	)	$	(5.85	)