Statements of Changes in Stockholders' Equity - USD ($)	Total	Additional Paid-In Capital	Accumulated Deficit	Convertible Preferred Stock [Member]	Common Stock
Beginning Balance at Dec. 31, 2018	$ 6,097,811	$ 197,114,310	$ (191,016,591)	$ 18	$ 74
Beginning Balance (in shares) at Dec. 31, 2018				17,513.63	738,029
Stock-based compensation expense	190,331	190,331
Conversion of Stock, Shares Converted				17,313.63
Conversion of Stock, Amount Converted		(48)		$ (17)
Issuance of common stock upon conversion of preferred stock					$ 65
Issuance of common stock upon conversion of preferred stock (in shares)					(658,314)
Issuance of common stock under employees stock purchase plan	15,106	15,105
Net income (loss)	(3,773,014)		(3,773,014)
Ending Balance at Dec. 31, 2019	2,530,234	197,319,698	(194,789,605)	$ 1	$ 140
Ending Balance (in shares) at Dec. 31, 2019				200.00	1,400,674
Stock-based compensation expense	599,117	599,117
Stock Issued During Period, Value, New Issues	4,143,431	4,143,197			$ 234
Shares Issued, Value, Share-based Payment Arrangement, after Forfeiture	43,751	43,748			$ 3
Shares Issued, Shares, Share-based Payment Arrangement, after Forfeiture					31,000
Issuance of common stock under employees stock purchase plan	23,437	23,435			$ 23,437
Issuance of common stock under employee stock purchase plan (in shares)					13,446
Net income (loss)	(2,092,195)		(2,092,195)
Ending Balance at Dec. 31, 2020	$ 5,247,775	$ 202,129,195	$ (196,881,800)	$ 1	$ 379
Ending Balance (in shares) at Dec. 31, 2020				200.00	3,793,739