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Income Taxes Income Taxes - Effective Income Tax Rate Reconciliation (Details)
12 Months Ended
Dec. 31, 2017
Dec. 31, 2016
Income Tax Disclosure [Abstract]    
Federal tax provision (benefit) rate 34.00% 34.00%
State tax provision, net of federal provision (5.90%) (4.20%)
Permanent items (0.10%) (0.20%)
Federal research and development credits (0.70%) (0.90%)
Change in statutory tax rate 150.30% 0.00%
Valuation allowance (109.60%) 39.30%
Effective income tax rate 0.00% 0.00%