Statements of Convertible Preferred Stock and Stockholders' Equity - USD ($)	Convertible Preferred Stock Series A [Member]	Convertible Preferred Stock Series B [Member]	Common Stock [Member]	Additional Paid-in Capital [Member]	Treasury Stock [Member]	Retained Earnings [Member]	Total
Beginning balance, value at Dec. 31, 2019	$ 5,758,190	$ 5,610	$ 68,530	$ 504,211,040	$ (205,999)	$ (481,312,774)	$ 22,766,407
Beginning balance, shares at Dec. 31, 2019	23,110	5,610,121	68,529,623
Issuance of common stock			$ 3,863	15,057,950			15,061,813
Issuance of common stock, shares			3,863,314
Share-based compensation			$ 149	3,169,199			3,169,348
Share-based compensation, shares			147,989
Components of net loss						(6,646,459)	(6,646,459)
Employee stock purchase plan			$ 32	119,910			119,942
Employee stock purchase plan, shares			32,467
Preferred stock conversion	$ (152,867)		$ 1,120	151,747			152,867
Preferred stock conversion, shares	(597)		1,120,810
Ending balance, value at Dec. 31, 2020	$ 5,605,323	$ 5,610	$ 73,694	522,709,846	(205,999)	(487,959,233)	34,623,918
Ending balance, shares at Dec. 31, 2020	22,513	5,610,121	73,694,203
Issuance of common stock			$ 333	429,473			429,806
Issuance of common stock, shares			332,232
Share-based compensation			$ 325	9,362,582			9,362,907
Share-based compensation, shares			325,954
Components of net loss						(10,715,623)	(10,715,623)
Employee stock purchase plan			$ 20	117,585			117,605
Employee stock purchase plan, shares			19,699
Preferred stock conversion	$ (21,555)		$ 246	21,309			21,555
Preferred stock conversion, shares	(126)		246,152
Ending balance, value at Dec. 31, 2021	$ 5,583,768	$ 5,610	$ 74,618	$ 532,640,795	$ (205,999)	$ (498,674,856)	$ 33,840,168
Ending balance, shares at Dec. 31, 2021	22,387	5,610,121	74,618,240