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Statements of Cash Flows (USD $)
12 Months Ended
Dec. 31, 2011
Dec. 31, 2010
Dec. 31, 2009
Cash flows from operating activities      
Net loss $ (32,031,175) $ (19,923,487) $ (27,494,457)
Adjustments to reconcile net loss to cash used in operating activities:      
Depreciation 1,462,238 1,697,694 2,050,507
Amortization 299,833 230,459 133,333
Amortization of warrants 1,331,549 1,652,672 2,346,027
Share-based compensation 2,487,441 2,049,606 4,229,183
Loss on asset disposal 86,278 5,039 557,152
Impairment charge 0 0 338,821
Non-cash expense (royalty income), net (2,353,718) (3,381,424) (1,983,414)
Warrant adjustment (3,416,383) (600,816) (911,977)
Changes in operating assets and liabilities:      
Accounts receivable 2,811,531 (2,762,921) (1,413,640)
Other receivables 28,495 65,175 290,233
Inventories (594,576) (1,075,075) 3,851,283
Prepaid expenses and other current assets 827,297 522,924 53,238
Other assets (2,223) (33,426) 93,270
Accounts payable (3,186,001) 4,937,129 (680,723)
Accrued liabilities (1,090,072) (1,221,120) (866,678)
Deferred revenue 1,775,856 (1,060,903) (2,761,929)
Other liabilities (5,648) (11,271) (138,892)
Net cash used in operating activities (31,569,278) (18,909,745) (22,308,663)
Cash flows from investing activities      
Purchase of equipment (1,031,749) (715,770) (1,484,192)
Net cash used in investing activities (1,031,749) (715,770) (1,484,192)
Cash flows from financing activities      
Proceeds from term note 0 10,000,000 0
Payments under term note (2,000,000) (333,333) (666,667)
Proceeds from revolving line of credit 77,109,376 58,034,809 3,000,000
Payments of revolving line of credit (72,818,866) (57,503,298) (6,234,822)
Proceeds from Cowen Debt 14,317,397 0 0
Payments under Biosense (5,540,373) (2,071,139) 0
Proceeds from issuance of stock and warrants, net of issuance costs 239,593 16,200,745 27,885,237
Net cash provided by financing activities 11,307,127 24,327,784 23,983,748
Net increase (decrease) in cash and cash equivalents (21,293,900) 4,702,269 190,893
Cash and cash equivalents at beginning of period 35,248,819 30,546,550 30,355,657
Cash and cash equivalents at end of period 13,954,919 35,248,819 30,546,550
Supplemental disclosures of cash flow information:      
Interest paid $ 859,494 $ 140,253 $ 864,279