-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
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 F9Sk2Ean42VlTlUV/bZhAQ==

<SEC-DOCUMENT>0001140361-10-047479.txt : 20101130
<SEC-HEADER>0001140361-10-047479.hdr.sgml : 20101130
<ACCEPTANCE-DATETIME>20101130172529
ACCESSION NUMBER:		0001140361-10-047479
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20101129
FILED AS OF DATE:		20101130
DATE AS OF CHANGE:		20101130

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Liedberg Michael B
		CENTRAL INDEX KEY:			0001297007

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-50845
		FILM NUMBER:		101222597

	MAIL ADDRESS:	
		STREET 1:		720 SW WASHINGTON STREET
		STREET 2:		SUITE 550
		CITY:			PORTLAND
		STATE:			OR
		ZIP:			97205

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			McCormick & Schmicks Seafood Restaurants Inc.
		CENTRAL INDEX KEY:			0001288741
		STANDARD INDUSTRIAL CLASSIFICATION:	RETAIL-EATING PLACES [5812]
		IRS NUMBER:				201193199
		FISCAL YEAR END:			1229

	BUSINESS ADDRESS:	
		STREET 1:		1414 NW NORTHRUP STREET, SUITE 700
		CITY:			PORTLAND
		STATE:			OR
		ZIP:			97209
		BUSINESS PHONE:		503-226-3440

	MAIL ADDRESS:	
		STREET 1:		1414 NW NORTHRUP STREET, SUITE 700
		CITY:			PORTLAND
		STATE:			OR
		ZIP:			97209

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	McCormick & Schmick Holdings, L.L.C.
		DATE OF NAME CHANGE:	20040427
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>doc1.xml
<DESCRIPTION>FORM 4
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0303</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2010-11-29</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0001288741</issuerCik>
        <issuerName>McCormick &amp; Schmicks Seafood Restaurants Inc.</issuerName>
        <issuerTradingSymbol>MSSR</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001297007</rptOwnerCik>
            <rptOwnerName>Liedberg Michael B</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>720 SW WASHINGTON STREET, SUITE 550</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>PORTLAND</rptOwnerCity>
            <rptOwnerState>OR</rptOwnerState>
            <rptOwnerZipCode>97205</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>Exec VP of Operations</officerTitle>
            <otherText></otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2010-11-29</value>
            </transactionDate>
            <deemedExecutionDate></deemedExecutionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>S</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>703</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>8.1517</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>1146</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <derivativeTable></derivativeTable>

    <footnotes></footnotes>

    <remarks></remarks>

    <ownerSignature>
        <signatureName>/s/ Douglas K. Fettig, Attorney-in-Fact</signatureName>
        <signatureDate>2010-11-30</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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