X0306 4 2023-01-25 0 0001287865 MEDICAL PROPERTIES TRUST INC MPW 0001665881 Hanna James Kevin 1000 URBAN CENTER DRIVE BIRMINGHAM AL 35242 0 1 0 0 VP, Controller & CAO Common stock, par value $0.001 2023-01-25 4 A 0 3666 0 A 113192 D Common stock, par value $0.001 2023-01-25 4 A 0 2750 0 A 115942 D Common stock, par value $0.001 2023-01-25 4 F 0 4203 11.14 D 111739 D Represents additional shares earned under the 2020 performance award based on the Company's actual performance as compared to the performance hurdles defined in the award agreement. The shares vested in January 2023. Represents additional shares earned under the 2022 performance award based on the Company's actual performance as compared to the performance hurdles defined in the award agreement. The shares vested in January 2023. Represents shares withheld upon vesting of restricted stock to satisfy tax withholding obligations. This does not constitute a sale transaction. W. Zachary Riddle, by power of attorney 2023-01-25