10-Q

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM 10-Q

(Mark one)

☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

For the quarterly period ended March 31, 2023

or

☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

For the transition period from___ to___

Commission file number: 001-40674

MaxCyte, Inc.

(Exact name of registrant as specified in its charter)

Delaware	52-2210438
(State or other jurisdiction of incorporation or organization)	(I.R.S. Employer Identification No.)

9713 Key West Avenue, Suite 400

Rockville, Maryland 20850

(Address of principal executive offices)

Registrant’s telephone number, including area code: (301) 944-1700

N/A

(Former name, former address and former fiscal year, if changed since last report)

Securities registered pursuant to Section 12(b) of the Act:

Title of each class	Trading Symbol(s)	Name of each exchange on which registered
Common stock, par value $0.01 per share	MXCT	The Nasdaq Stock Market LLC

Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days. Yes☒ No☐

Indicate by check mark whether the registrant has submitted electronically every Interactive Data File required to be submitted pursuant to Rule 405 of Regulation S-T (§ 232.405 of this chapter) during the preceding 12 months (or for such shorter period that the registrant was required to submit such files). Yes ☒ No ☐

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company, or an emerging growth company. See the definitions of “large accelerated filer,” “accelerated filer,” “smaller reporting company,” and “emerging growth company” in Rule 12b-2 of the Exchange Act.

Large accelerated filer	☐	Accelerated filer	☐	Non-accelerated filer	☒
Smaller reporting company	☒	Emerging growth company	☒

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐

Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act). Yes ☐ No ☒

As of May 2, 2023, the registrant had 103,050,899 shares of common stock, $0.01 par value per share, issued and outstanding.

Table of Contents

		Page No
PART I. FINANCIAL INFORMATION		3
Item 1.	Financial Statements (Unaudited)	3
	Condensed Consolidated Balance Sheets	3
	Condensed Consolidated Statements of Operations	4
	Condensed Consolidated Statements of Changes in Stockholders’ Equity	5
	Condensed Consolidated Statements of Cash Flows	6
	Notes to Unaudited Condensed Consolidated Financial Statements	7
Item 2.	Management’s Discussion and Analysis of Financial Condition and Results of Operations	16
Item 3.	Quantitative and Qualitative Disclosures About Market Risk	27
Item 4.	Controls and Procedures	27
PART II. OTHER INFORMATION		28
Item 1.	Legal Proceedings	28
Item 1A.	Risk Factors	28
Item 2.	Unregistered Sales of Equity Securities and Use of Proceeds	28
Item 3.	Defaults Upon Senior Securities	29
Item 4.	Mine Safety Disclosures	29
Item 5.	Other Information	29
Item 6.	Exhibits	30
Signatures		31

2

Part I. FINANCIAL INFORMATION

Item 1. Condensed Consolidated Financial Statements (Unaudited)

MaxCyte, Inc.

Condensed Consolidated Balance Sheets

	March 31,		December 31,
	2023		2022
		(Unaudited)		(Note 2)
Assets
Current assets:
Cash and cash equivalents	$	37,833,400	$	11,064,700
Short-term investments, at amortized cost		186,819,300		216,274,900
Accounts receivable		8,294,800		11,654,600
Accounts receivable - TIA (Note 7)		996,600		1,912,400
Inventory		10,264,900		8,580,800
Prepaid expenses and other current assets		2,230,600		2,778,800
Total current assets		246,439,600		252,266,200
Property and equipment, net		24,947,900		23,724,700
Right of use asset - operating leases		9,757,600		9,853,500
Other assets		399,300		809,000
Total assets	$	281,544,400	$	286,653,400
Liabilities and stockholders’ equity
Current liabilities:
Accounts payable	$	3,502,100	$	531,800
Accrued expenses and other		6,912,900		8,025,300
Operating lease liability, current		475,200		156,800
Deferred revenue, current portion		5,749,200		6,712,600
Total current liabilities		16,639,400		15,426,500
Operating lease liability, net of current portion		15,777,200		15,938,100
Other liabilities		1,309,000		1,321,600
Total liabilities		33,725,600		32,686,200
Commitments and contingencies (Note 7)
Stockholders’ equity
Preferred stock, $0.01 par value; 5,000,000 shares authorized and no shares issued and outstanding at March 31, 2023 and December 31, 2022		—		—
Common stock, $0.01 par value; 400,000,000 shares authorized, 102,904,745 and 102,397,913 shares issued and outstanding at March 31, 2023 and December 31, 2022, respectively		1,029,100		1,024,000
Additional paid-in capital		395,546,600		390,818,500
Accumulated deficit		(148,756,900)		(137,875,300)
Total stockholders’ equity		247,818,800		253,967,200
Total liabilities and stockholders’ equity	$	281,544,400	$	286,653,400

See accompanying notes to unaudited condensed consolidated financial statements.

3

MaxCyte, Inc.

Unaudited Condensed Consolidated Statements of Operations

	Three Months Ended March 31,
	2023		2022
Revenue	$	8,576,300	$	11,587,300
Cost of goods sold		999,800		1,062,600
Gross profit		7,576,500		10,524,700
Operating expenses:
Research and development		6,046,500		3,765,300
Sales and marketing		6,296,100		3,838,700
General and administrative		7,498,900		6,632,500
Depreciation and amortization		912,200		447,300
Total operating expenses		20,753,700		14,683,800
Operating loss		(13,177,200)		(4,159,100)
Other income:
Interest income		2,295,600		91,800
Total other income		2,295,600		91,800
Net loss	$	(10,881,600)	$	(4,067,300)
Basic and diluted net loss per share	$	(0.11)	$	(0.04)
Weighted average shares outstanding, basic and diluted		102,846,036		101,305,943

See accompanying notes to unaudited condensed consolidated financial statements.

4

MaxCyte, Inc.

Unaudited Condensed Consolidated Statements of Changes in Stockholders’ Equity

								Total
	Common Stock			Additional		Accumulated		Stockholders’
	Shares	Amount		Paid-in Capital		Deficit		Equity
Balance at January 1, 2022	101,202,705	$	1,012,000	$	376,189,600	$	(114,304,500)	$	262,897,100
Stock-based compensation expense	—		—		2,462,400		—		2,462,400
Exercise of stock options	307,187		3,100		889,500		—		892,600
Net loss	—		—		—		(4,067,300)		(4,067,300)
Balance at March 31, 2022	101,509,892	$	1,015,100	$	379,541,500	$	(118,371,800)	$	262,184,800

								Total
	Common Stock			Additional		Accumulated		Stockholders’
	Shares	Amount		Paid-in Capital		Deficit		Equity
Balance at January 1, 2023	102,397,913	$	1,024,000	$	390,818,500	$	(137,875,300)	$	253,967,200
Stock-based compensation expense	—		—		3,276,600		—		3,276,600
Exercise of stock options	506,832		5,100		1,451,500		—		1,456,600
Net loss	—		—		—		(10,881,600)		(10,881,600)
Balance at March 31, 2023	102,904,745	$	1,029,100	$	395,546,600	$	(148,756,900)	$	247,818,800

See accompanying notes to unaudited condensed consolidated financial statements.

5

MaxCyte, Inc.

Unaudited Condensed Consolidated Statements of Cash Flows

	Three Months Ended March 31,
	2023		2022
Cash flows from operating activities:
Net loss	$	(10,881,600)	$	(4,067,300)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization		961,700		487,400
Net book value of consigned equipment sold		16,800		32,800
Stock-based compensation		3,276,600		2,462,400
Amortization of discounts on short-term investments		(1,730,100)		(33,200)
Changes in operating assets and liabilities:
Accounts receivable		3,359,800		(1,750,800)
Accounts receivable - TIA		915,800		(2,119,200)
Inventory		(1,706,000)		(1,377,000)
Prepaid expense and other current assets		548,200		1,117,200
Right of use asset – operating leases		95,900		(5,212,600)
Other assets		409,700		(738,200)
Accounts payable, accrued expenses and other		1,227,000		(150,500)
Operating lease liability		157,500		7,569,000
Deferred revenue		(963,400)		84,900
Other liabilities		(12,600)		900
Net cash used in operating activities		(4,324,700)		(3,694,200)
Cash flows from investing activities:
Purchases of short-term investments		(57,814,300)		—
Maturities of short-term investments		89,000,000		200,796,000
Purchases of property and equipment		(1,558,000)		(5,999,500)
Proceeds from sale of equipment		9,100		—
Net cash provided by investing activities		29,636,800		194,796,500
Cash flows from financing activities:
Proceeds from exercise of stock options		1,456,600		892,600
Net cash provided by financing activities		1,456,600		892,600
Net increase in cash and cash equivalents		26,768,700		191,994,900
Cash and cash equivalents, beginning of period		11,064,700		47,782,400
Cash and cash equivalents, end of period	$	37,833,400	$	239,777,300
Supplemental disclosure of non-cash investing and financing activities:
Property and equipment purchases included in accounts payable	$	630,900	$	43,200

See accompanying notes to unaudited condensed consolidated financial statements.

6

MaxCyte, Inc.

Notes to Condensed Consolidated Financial Statements

(Unaudited)

1.   Organization and Description of Business

MaxCyte, Inc. (the “Company” or “MaxCyte”) was incorporated as a majority owned subsidiary of EntreMed, Inc. (“EntreMed”) on July 31, 1998, under the laws and provisions of the state of Delaware and commenced operations on July 1, 1999. In November 2002, MaxCyte was recapitalized and EntreMed was no longer deemed to control the Company.

MaxCyte is a global life sciences company focused on advancing the discovery, development and commercialization of next-generation cell therapies. MaxCyte leverages its proprietary cell engineering technology platform to enable the programs of its biotechnology and pharmaceutical company customers who are engaged in cell therapy, including gene editing and immuno-oncology, as well as in drug discovery and development and biomanufacturing. The Company licenses and sells its instruments and technology and sells its consumables to developers of cell therapies and to pharmaceutical and biotechnology companies for use in drug discovery and development and biomanufacturing.

The Company’s registration statement on Form S-1 related to its initial public offering of common stock in the United States (the “IPO”) was declared effective on July 29, 2021, and the Company’s common stock began trading on the Nasdaq Global Select Market on July 30, 2021. On August 3, 2021, the Company issued and sold 15,525,000 shares of common stock in the IPO at a price to the public of $13.00 per share, inclusive of 2,025,000 shares issued pursuant to the full exercise of the underwriters’ option to purchase additional shares. The IPO generated gross proceeds to the Company of $201.8 million. The Company received aggregate net proceeds of $184.3 million from the IPO after deducting aggregate underwriting commissions and offering costs of $17.6 million.

2.    Summary of Significant Accounting Policies

Basis of Presentation

The accompanying unaudited condensed consolidated interim financial statements have been prepared in accordance with accounting principles generally accepted in the United States of America (“U.S. GAAP”) for interim financial information and pursuant to the instructions to Form 10-Q and Article 10 of Regulation S-X of the United States Securities and Exchange Commission (the “SEC”). In the Company’s opinion, the accompanying unaudited condensed consolidated financial statements include all adjustments, consisting of normal recurring adjustments, which are necessary to present fairly the financial position, results of operations, and cash flows as of and for the periods presented. The condensed consolidated balance sheet at December 31, 2022 has been derived from audited consolidated financial statements as of that date. The unaudited condensed consolidated results of operations are not necessarily indicative of the results that may occur for the full fiscal year or any other future year or period. Certain information and footnotes disclosure normally included in financial statements prepared in accordance with U.S. GAAP have been omitted pursuant to instructions, rules, and regulations prescribed by the SEC. The Company believes that the disclosures provided herein are adequate to make the information presented not misleading when these unaudited interim condensed consolidated financial statements are read in conjunction with the audited consolidated financial statements and notes included in the Company’s Annual Report on Form 10-K filed with the SEC on March 15, 2023.

Significant Accounting Policies

The Company’s significant accounting policies are disclosed in the footnotes to its audited consolidated financial statements for the year ended December 31, 2022 included in its Annual Report on Form 10-K and have not materially changed during the three months ended March 31, 2023.

Basis of Consolidation

The consolidated financial statements include the accounts of the Company and its wholly-owned subsidiary. All significant intercompany balances have been eliminated in consolidation.

7

Concentration of Risk

The Company maintains its cash and cash equivalents with two financial institutions that management believes to be of high credit quality. At times the Company’s cash balances may exceed federally insured limits and cash may also be deposited in foreign bank accounts that are not covered by federal deposit insurance. The Company does not believe that this results in any significant credit risk beyond the normal credit risk associated with commercial banking relationships.

Significant customers are those that accounted for 10% or more of the Company’s total revenue for the period or accounts receivable as of the end of a reporting period. During the three months ended March 31, 2023, two customers represented 23% and 11% of revenue, respectively. During the three months ended March 31, 2022, one customer represented 33% of revenue. As of March 31, 2023, two customers accounted for 23% and 12% of accounts receivable, respectively. As of December 31, 2022, one customer accounted for 14% of accounts receivable.

Certain components included in the Company’s products are obtained from a single source or a limited group of suppliers. During the three months ended March 31, 2023 and 2022, the Company purchased 60% and 39%, respectively, of its inventory from one supplier. As of March 31, 2023, amounts payable to one supplier totaled 21% of total accounts payable. At December 31, 2022, amounts payable to two suppliers totaled 34% of total accounts payable.

Accounts Receivable

Accounts receivable are reduced by an allowance for doubtful accounts, if needed. The Company determined that no allowance was necessary at March 31, 2023 or December 31, 2022.

Foreign Currency

The Company’s functional currency is the US dollar; transactions denominated in foreign currencies are subject to currency risk. The Company recognized $6,100 in foreign currency transaction gains and $23,200 in foreign currency transaction losses for the three months ended March 31, 2023 and 2022, respectively.

Leases

For transactions in which the Company is the lessee, at the inception of a contract, the Company determines if the arrangement is, or contains, a lease. See Note 7 for additional details about leases under which the Company is the lessee.

All transactions in which the Company is the lessor are short-term (one year or less) and have been classified as operating leases. All leases require upfront payments covering the full period of the lease and thus, there are no future payments expected to be received from existing leases. See Note 3 for details on revenue recognition related to lease agreements.

Loss Per Share

Basic loss per share is computed by dividing net loss available to common stockholders by the weighted average number of shares of common stock outstanding during the period.

For periods of net income, and when the effects are not anti-dilutive, diluted earnings per share is computed by dividing net income available to common stockholders by the weighted-average number of shares outstanding plus the impact of all potential dilutive common shares, consisting primarily of common stock options and restricted stock units, and in the prior year periods stock purchase warrants, using the treasury stock method.

For periods of net loss, diluted loss per share is calculated similarly to basic loss per share because the impact of all dilutive potential common shares is anti-dilutive. The number of anti-dilutive shares excluded from the computation of diluted loss per share, consisting of shares underlying stock options and restricted stock units, was 17.1 million for the three months ended March 31, 2023 and 15.1 million for the three months ended March 31, 2022.

8

Recent Accounting Pronouncements

New Accounting Pronouncements Adopted

In June 2016, the Financial Accounting Standards Board (“FASB”) issued guidance with respect to measuring credit losses on financial instruments, including trade receivables. The guidance eliminates the probable initial recognition threshold that was previously required prior to recognizing a credit loss on financial instruments. The credit loss estimate can now reflect an entity’s current estimate of all future expected credit losses. Under the previous guidance, an entity only considered past events and current conditions. The current guidance is effective for fiscal years beginning after December 15, 2022, including interim periods within those fiscal years. The adoption of certain amendments of this guidance must be applied on a modified retrospective basis and the adoption of the remaining amendments must be applied on a prospective basis. The Company adopted this new accounting pronouncement effective on January 1, 2023, and the adoption did not have a material impact on its consolidated financial statements.

The Company has evaluated all other issued and unadopted Accounting Standards Updates and believes the adoption of these standards will not have a material impact on its results of operations, financial position, or cash flows.

3.    Revenue

Revenue is principally from the sale of instruments and processing assemblies, and extended warranties and the lease of instruments, which lease agreements also include customer-specific milestone payments. In some arrangements, products and services have been sold together representing distinct performance obligations. In these arrangements the Company allocates the sale price to the various performance obligations in the arrangement on a relative selling price basis. Under this basis, the Company determines the estimated selling price of each performance obligation in a manner that is consistent with that used to determine the price to sell the deliverable on a standalone basis.

Revenue is recognized at the time control is transferred to the customer and the performance obligation is satisfied. Revenue from the sale of instruments and processing assemblies is generally recognized at the time of shipment to the customer, provided that no significant vendor obligations remain and collectability is reasonably assured. Revenue from equipment leases is recognized ratably over the contractual term of the lease agreement and when specific milestones are achieved by a customer. Licensing fee revenue is recognized ratably over the license period. Revenue from fees for research services is recognized when services have been provided.

Disaggregation of Revenue

The following table depicts the disaggregation of revenue by type of contract:

	Three months ended March 31, 2023
	Revenue from		Revenue
	Contracts		from
	with		Lease		Total
	Customers		Elements		Revenue
Product sales	$	4,789,700	$	—	$	4,789,700
Lease elements		—		3,612,800		3,612,800
Other		173,800		—		173,800
Total	$	4,963,500	$	3,612,800	$	8,576,300

9

	Three months ended March 31, 2022
	Revenue from		Revenue
	Contracts		from
	with		Lease		Total
	Customers		Elements		Revenue
Product sales	$	6,567,600	$	—	$	6,567,600
Lease elements		—		4,730,000		4,730,000
Other		289,700		—		289,700
Total	$	6,857,300	$	4,730,000	$	11,587,300

Additional Disclosures Relating to Revenue from Contracts with Customers

Deferred revenue represents payments received for performance obligations not yet satisfied and is presented as current or long-term in the accompanying condensed consolidated balance sheets based on the expected timing and satisfaction of the underlying goods or services. Deferred revenue was $6.1 million and $7.0 million as of March 31, 2023 and December 31, 2022, respectively. During the three months ended March 31, 2023 and 2022, the Company recognized $2.6 million and $2.6 million, respectively, of revenue that was included in deferred revenue at the beginning of such periods.

Remaining contract consideration for which revenue has not been recognized due to unsatisfied performance obligations with a duration greater than one year at March 31, 2023 was $405,200, of which the Company expects to recognize $94,700 in one year or less, $94,700 in one to two years, $47,300 in two to three years, and $168,500 thereafter.

For the three months ended March 31, 2023 and 2022, the Company did not incur, and therefore did not defer, any material incremental costs to obtain contracts or costs to fulfill contracts.

4.    Stockholders’ Equity

Common Stock

During the year ended December 31, 2022, the Company issued 1,195,208 shares of common stock as a result of stock option exercises, receiving gross proceeds of $2.9 million.

During the three months ended March 31, 2023, the Company issued 506,832 shares of common stock as a result of stock option exercises, receiving gross proceeds of $1.5 million.

Preferred Stock

The Company’s certificate of incorporation authorizes the issuance of up to 5,000,000 shares of preferred stock, par value $0.01 per share. As of March 31, 2023 and December 31, 2022, no shares of preferred stock were issued or outstanding.

Stock Incentive Plans

The Company adopted the MaxCyte, Inc. Long-Term Incentive Plan (the “2016 Plan”) in January 2016 to provide for the awarding of (i) stock options, (ii) restricted stock, (iii) incentive shares, and (iv) performance awards to employees, officers, and directors of the Company and to other individuals as determined by the board of directors.

In December 2021, the Company adopted the MaxCyte, Inc. 2021 Inducement Plan (the “Inducement Plan”) to provide for the awarding of (i) non-qualified stock options; (ii) stock appreciation rights; (iii) restricted stock awards; (iv) restricted stock unit awards; (v) performance awards; and (vi) other awards only to persons eligible to receive grants of awards who satisfy the standards for inducement grants under Nasdaq Marketplace Rule 5635(c)(4) or 5635(c)(3), if applicable, and the related guidance under Nasdaq IM 5635-1. The board of directors reserved 2,500,000 shares for issuance under the Inducement Plan.

10

In May 2022, the Company’s board of directors adopted, and in June 2022 the Company’s stockholders approved, the MaxCyte, Inc. 2022 Equity Incentive Plan (the “2022 Plan”) to provide for the awarding of (i) incentive stock options, (ii) non-qualified stock options, (iii) stock appreciation rights, (iv) restricted stock awards, (v) restricted stock unit awards, (vi) performance awards, and (vii) other awards. Following the approval of the 2022 Plan, no additional awards can be granted under the 2016 Plan or the Inducement Plan, but all outstanding awards will continue to remain subject to the terms of the applicable plan.

Upon the effectiveness of the 2022 Plan, a total of 3,692,397 shares were initially reserved for issuance pursuant to future awards under the 2022 Plan, consisting of 1,928,000 new shares and 1,764,397 shares previously available under the 2016 Plan. If and to the extent that outstanding options under the 2016 Plan or the Inducement Plan are forfeited, the shares underlying such forfeited options will become available for issuance under the 2022 Plan.

The Company has not issued performance awards under any plan.

At March 31, 2023 and December 31, 2022, there were 733,225 and 3,455,656 shares, respectively, available to be issued under the 2022 Plan.

The value of an equity award is recognized as expense on a straight-line basis over the requisite service period. At March 31, 2023, total unrecognized compensation expense was $33,142,200, which will be recognized over an estimated weighted average period of 2.73 years.

Stock Options

The weighted-average fair value of the stock options granted during the three months ended March 31, 2023 and 2022 was estimated to be $2.04 and $6.93, respectively per option share.

Restricted Stock Units (“RSUs”)

The weighted-average fair value of the RSUs granted during the three months ended March 31, 2023 was estimated to be $4.35 per RSU. The Company did not issue any RSUs before July 2022.

The Company recorded stock-based compensation expense in the following expense categories of its condensed consolidated statements of operations:

	Three months ended March 31,
	2023		2022
General and administrative	$	1,466,700	$	1,292,100
Sales and marketing		1,065,500		662,800
Research and development		744,400		507,500
Total	$	3,276,600	$	2,462,400

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5. Consolidated Balance Sheet Components

Inventory

Inventory is carried at the lower of cost or net realizable value. The following tables show the components of inventory:

	March 31,		December 31,
	2023		2022
Raw materials inventory	$	6,044,400	$	5,650,500
Finished goods inventory		3,549,500		2,930,300
Work in progress		671,000		—
Total inventory	$	10,264,900	$	8,580,800

The Company determined that no allowance for inventory obsolescence was necessary at March 31, 2023 or December 31, 2022.

Property and Equipment

Property and equipment are stated at cost. Depreciation is computed using the straight-line method. Leasehold improvements are amortized over the shorter of the estimated lease term or useful life.

Property and equipment include capitalized costs to develop internal-use software.  Applicable costs are capitalized during the development stage of the project and include direct internal costs, third-party costs and allocated interest expenses as appropriate.

Property and equipment consisted of the following:

	March 31,		December 31,
	2023		2022
Leasehold improvements	$	14,334,900	$	14,195,500
Furniture and equipment		11,516,400		9,516,500
Internal-use software		3,800,400		3,220,500
Instruments		2,430,300		2,440,300
Construction in process and internal-use software		82,300		627,400
Accumulated depreciation and amortization		(7,216,400)		(6,275,500)
Property and equipment, net	$	24,947,900	$	23,724,700

During the three months ended March 31, 2023 and 2022, the Company transferred $27,000 and $49,400, respectively, of instruments previously classified as inventory to property and equipment leased to customers.

For the three months ended March 31, 2023 and 2022, the Company incurred depreciation and amortization expense of $961,700 and $487,400, respectively.

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6.    Fair Value

The Company’s condensed consolidated balance sheets include various financial instruments (primarily cash and cash equivalents, accounts receivable and accounts payable) that are carried at cost, which approximates fair value due to the short-term nature of the instruments.

Financial Assets and Liabilities Measured at Fair Value on a Recurring Basis

The Company had no financial assets or liabilities measured at fair value on a recurring basis as of March 31, 2023 or December 31, 2022.

Financial Assets and Liabilities Measured at Fair Value on a Non-Recurring Basis

Money market funds, US Treasury securities and government agency bonds, commercial paper and corporate debt instruments classified as held-to-maturity are measured at fair value on a non-recurring basis when they are deemed to be impaired on an other-than-temporary basis. The Company periodically reviews investments to assess for credit impairment. Based on its assessment, all unrecognized holding losses were due to factors other than credit loss, such as changes in interest rates. Therefore, no impairment was recognized during the three months ended March 31, 2023 or 2022.

The following table summarizes the Company’s financial instruments that were measured at fair value on a non-recurring basis at March 31, 2023:

				Gross		Gross
		Amortized		unrecognized		unrecognized		Aggregate
Description	Classification	cost		holding gains		holding losses		fair value
Money market funds and cash equivalents	Cash equivalents	$	28,327,600	$	—	$	—	$	28,327,600
Commercial paper	Cash equivalents		4,978,400		1,200				4,979,600
Commercial paper	Short-term investments		143,177,100		135,000		(62,000)		143,250,100
Corporate debt	Short-term investments		5,812,300		—		(14,900)		5,797,400
US Treasury securities and government agency bonds	Short-term investments		37,829,900		2,600		(122,100)		37,710,400
Total cash equivalents and short-term investments		$	220,125,300	$	138,800	$	(199,000)	$	220,065,100

The following table summarizes the Company’s financial instruments that were measured at fair value on a non-recurring basis at December 31, 2022:

				Gross		Gross
		Amortized		unrecognized		unrecognized		Aggregate
Description	Classification	cost		holding gains		holding losses		fair value
Money market funds and cash equivalents	Cash equivalents	$	5,741,800	$	—	$	—	$	5,741,800
Commercial paper	Short-term investments		172,740,700		156,400		(235,700)		172,661,400
Corporate debt	Short-term investments		5,792,000		—		(42,700)		5,749,300
US Treasury securities and government agency bonds	Short‑term investments		37,742,200		4,500		(196,100)		37,550,600
Total cash equivalents and short-term investments		$	222,016,700	$	160,900	$	(474,500)	$	221,703,100

Non-Financial Assets and Liabilities Measured at Fair Value on a Recurring Basis

The Company has no non-financial assets and liabilities that are measured at fair value on a recurring basis.

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Non-Financial Assets and Liabilities Measured at Fair Value on a Non-Recurring Basis

The Company measures its long-lived assets, including property and equipment, at fair value on a non-recurring basis. These assets are recognized at fair value when they are deemed to be impaired. No fair value impairment was recognized during the three months ended March 31, 2023 and 2022.

7.  Commitments and Contingencies

Operating Leases

The Company was a party to various leases for office and laboratory and other space that were terminated in 2022. A member of the Company’s board of directors was previously the Chief Executive Officer and a member of the board of directors of the lessor of certain of these leases for which the rent payments totaled $163,700 in the three months ended March 31, 2022.

In May 2021, the Company entered into a lease for its new headquarters (the “New Headquarters Lease”), consisting of an operating lease agreement, as amended, for new office, laboratory, manufacturing and other space. The New Headquarters Lease consists of three phases, with Phase 1 having commenced in December 2021 and Phase 2 having commenced in the first quarter of 2022. Phase 3 is expected to begin in the second half of 2023. The lease term for all phases expires on August 31, 2035. The Company designed and constructed the leasehold improvements with the approval of the landlord. The New Headquarters Lease agreement includes a landlord-provided tenant improvement allowance (“TIA”) of $6.3 million to offset the cost of construction of leasehold improvements. As of March 31, 2023, the Company had received TIA reimbursements of $5.2 million. Under the New Headquarters Lease, the Company has three five-year options to extend the term of the lease. However, the Company is not reasonably certain to exercise any of these options. The total incremental non-cancellable lease payments under the New Headquarters Lease are approximately $29.6 million over the lease term.

The Company had no finance leases as of March 31, 2023 and December 31, 2022.

The components of lease cost and supplemental balance sheet information for the Company’s lease portfolio were as follows:

	Three months ended March 31,
	2023		2022
Operating lease cost	$	489,400	$	416,300
Short-term lease cost		10,000		12,100
Variable lease cost		165,200		75,400
Total lease cost	$	664,600	$	503,800

	As of March 31,		As of December 31,
	2023		2022
Operating leases
Assets:
Operating lease right of use assets	$	9,757,600	$	9,853,500
Liabilities
Current portion of operating lease liabilities	$	475,200	$	156,800
Operating lease liabilities, net of current portion		15,777,200		15,938,100
Total operating lease liabilities	$	16,252,400	$	16,094,900
Other information
Weighted-average remaining lease term (in years)		12.4		12.7
Weighted-average incremental borrowing rate		6.5%		6.5%

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As of March 31, 2023, maturities of lease liabilities that had commenced prior to March 31, 2023 were as follows:

	Operating Leases
Remainder of 2023	$	1,121,800
2024		1,734,500
2025		1,777,700
2026		1,822,100
2027		1,867,700
2028 and thereafter		15,963,200
Total undiscounted lease payments		24,287,000
Discount factor		(8,034,600)
Present value of lease liabilities	$	16,252,400

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Item 2. Management’s Discussion and Analysis of Financial Condition and Results of Operations

You should read the following discussion and analysis of our financial condition and results of operations in conjunction with our unaudited condensed consolidated financial statements and related notes thereto included in Part I, Item 1 of this Quarterly Report on Form 10-Q, our audited consolidated financial statements and related notes for the year ended December 31, 2022, included in our Annual Report on Form 10-K filed with the Securities and Exchange Commission (the “SEC”) on March 15, 2023, as well as the information contained under Management’s Discussion and Analysis of Financial Condition and Results of Operations and "Risk Factors" contained in the Annual Report on Form 10-K, and Part II, Item 1A "Risk Factors" of this Quarterly Report on Form 10-Q, and other information provided from time to time in our other filings with the SEC.

Special Note Regarding Forward-Looking Statements

This Quarterly Report on Form 10-Q contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. These statements about us and our industry involve substantial risks, uncertainties, and assumptions, including those described elsewhere in this report. All statements other than statements of historical facts contained in this report, including statements regarding our future results of operations or financial condition, business strategy and plans and objectives of management for future operations, are forward-looking statements. In some cases, you can identify forward-looking statements because they contain words such as “anticipate,” “believe,” “contemplate,” “continue,” “could,” “estimate,” “expect,” “intend,” “may,” “plan,” “potential,” “predict,” “project,” “should,” “target,” “will” or “would” or the negative of these words or other similar terms or expressions. These forward-looking statements include, but are not limited to, statements concerning the following:

● our expected future growth and the success of our business model;

● the potential payments we may receive pursuant to our Strategic Platform Licenses (“SPLs”);

● the size and growth potential of the markets for our products, and our ability to serve those markets, increase our market share and achieve and maintain industry leadership;

● the rate and degree of market acceptance of our products within the cell engineering market;

● the expected future growth of our manufacturing capabilities and sales, support and marketing capabilities;

● our ability to expand our customer base and enter into additional SPL partnerships;

● our ability to accurately forecast and manufacture appropriate quantities of our products to meet clinical or commercial demand;

● our expectations regarding development of the cell therapy market, including projected growth in adoption of non-viral delivery approaches and gene editing manipulation technologies;

● our expectation that partners will have access to capital markets to develop and commercialize their cell therapy programs;

● our ability to maintain our FDA Master File and Master Files and Technical Files in other countries and expand Master and Technical Files into additional countries;

● our research and development for any future products, including our intention to introduce new instruments and processing assemblies and move into new applications;

● the development, regulatory approval, and commercialization of competing products and our ability to compete with the companies that develop and sell such products;

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● our ability to retain and hire senior management and key personnel;

● regulatory developments in the United States and foreign countries;

● our expectations regarding the period during which we qualify as an emerging growth company under the JOBS Act (as defined below);

● our ability to develop and maintain our corporate infrastructure, including our internal controls;

● our financial performance and capital requirements;

● our expectations regarding our ability to obtain and maintain intellectual property protection for our products, as well as our ability to operate our business without infringing the intellectual property rights of others; and

● our use of available capital resources.

You should not rely on forward-looking statements as predictions of future events. We have based the forward-looking statements contained in this Quarterly Report primarily on our current expectations and projections about future events and trends that we believe may affect our business, financial condition and operating results. The outcome of the events described in these forward-looking statements is subject to risks, uncertainties and other factors described under the caption “Risk Factors” and elsewhere in our Annual Report on Form 10-K for the year ended December 31, 2022. Moreover, we operate in a very competitive and rapidly changing environment. New risks and uncertainties emerge from time to time, and it is not possible for us to predict all risks and uncertainties that could have an impact on the forward-looking statements contained in this report. The results, events and circumstances reflected in the forward-looking statements may not be achieved or occur, and actual results, events or circumstances could differ materially from those described in the forward-looking statements.

In addition, statements that “we believe” and similar statements reflect our beliefs and opinions on the relevant subject. These statements are based on information available to us as of the date of this Quarterly Report on Form 10-Q. And while we believe that information provides a reasonable basis for these statements, that information may be limited or incomplete. Our statements should not be read to indicate that we have conducted an exhaustive inquiry into, or review of, all relevant information. These statements are inherently uncertain, and investors are cautioned not to unduly rely on these statements.

The forward-looking statements made in this Quarterly Report on Form 10-Q relate only to events as of the date on which the statements are made. We undertake no obligation to update any forward-looking statements made in this Quarterly Report to reflect events or circumstances after the date of this Quarterly Report or to reflect new information or the occurrence of unanticipated events, except as required by law. We may not actually achieve the plans, intentions or expectations disclosed in our forward-looking statements, and you should not place undue reliance on our forward-looking statements. Our forward-looking statements do not reflect the potential impact of any future acquisitions, mergers, dispositions, joint ventures or investments.

You should read this Quarterly Report and the documents that we file from time to time with the SEC with the understanding that our actual future results, levels of activity, performance and events and circumstances may be materially different from what we expect.

In this Quarterly Report on Form 10-Q, unless the context requires otherwise, all references to “we,” “our,” “us,” “MaxCyte” and the “Company” refer to MaxCyte, Inc.

Overview

We are a leading commercial cell engineering company focused on providing enabling platform technologies to advance the discovery, development and commercialization of next-generation cell therapeutics and to support innovative cell-

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based research and development. Over more than two decades, we have developed and commercialized our proprietary Flow Electroporation® platform, which facilitates complex engineering of a wide variety of cells. Electroporation is a method of transfection, or the process of deliberately introducing molecules into cells, that involves applying an electric field in order to temporarily increase the permeability of the cell membrane. This precisely controlled increase in permeability allows the intracellular delivery of molecules, such as genetic material and proteins, that would not normally be able to cross the cell membrane as easily.

Our ExPERT platform, which is based on our Flow Electroporation technology, has been designed to address this rapidly expanding cell therapy market and can be utilized across the continuum of the high-growth cell therapy sector, from discovery and development through commercialization of next-generation, cell-based medicines. The ExPERT™ family of products includes four instruments, which we call the ATx™, STx™, GTx™ and VLx™, as well as a portfolio of proprietary related disposables and consumables. We launched the ExPERT VLx™ instrument for very large-scale cell engineering in September 2022. Our disposables and consumables include processing assemblies (“PAs”) designed for use with our instruments, as well as accessories supporting PAs such as electroporation buffer solution and software protocols. We have garnered meaningful expertise in cell engineering via our internal research and development efforts as well as our customer-focused commercial approach, which includes a growing application scientist team. The platform is also supported by a robust intellectual property portfolio with more than 160 granted U.S. and foreign patents and more than 105 pending patent applications worldwide.

From leading commercial cell therapy drug developers and top biopharmaceutical companies to top academic and government research institutions, including the U.S. National Institutes of Health, our customers have extensively validated our technology. We believe the features and performance of our platform have led to sustained customer engagement. Our existing customer base ranges from large biopharmaceutical companies, including all of the top 10, and 20 of the top 25, pharmaceutical companies based on 2021 global revenue, to hundreds of biotechnology companies and academic centers focused on translational research.

Since our inception, we have incurred significant operating losses. Our ability to generate revenue sufficient to achieve profitability will depend on the successful further development and commercialization of our products. We generated revenue of $8.6 million and incurred a net loss of $10.9 million for the three months ended March 31, 2023. As of March 31, 2023, we had an accumulated deficit of $148.8 million. We expect to continue to incur net losses as we focus on growing commercial sales of our products in both the United States and international markets, including growing our sales force, scaling our manufacturing operations, continuing research and development efforts to develop new products and further enhance our existing products.

Recent Developments

We have continued to enter into SPL agreements with our cell therapy customers. These agreements are discussed in more detail in “Results of Operations” below and provide us with revenue from instrument sales and leases and disposables sales as well as pre-commercial milestones based on progress of our partners’ programs through the clinic and sales-based payments upon commercialization of our partners’ programs. In the first three months of 2023, we signed an SPL agreement with Catamaran Bio. We continue to grow our SPL pipeline and, while the specific timing of any agreement is uncertain, we expect to sign additional SPL agreements in the future.

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Results of Operations

Comparison of the Three Months Ended March 31, 2023 and 2022

The following table sets forth our results of operations for the periods presented:

		Three Months Ended
		March 31,
		2023		2022
		(in thousands)
Total revenue	$	8,576	$	11,587
Cost of goods sold		1,000		1,063
Gross profit		7,577		10,525
Operating expense
Research and development		6,047		3,765
Sales and marketing		6,296		3,839
General and administrative		7,499		6,633
Depreciation and amortization		912		447
Total operating expense		20,754		14,684
Operating loss		(13,177)		(4,159)
Other income (expense)
Interest income		2,296		92
Total other income (expense)		2,296		92
Net loss	$	(10,882)	$	(4,067)

Revenue

We generate revenue principally from the sale of instruments and single-use PAs and buffer, and from the lease of instruments to our customers. Our SPL partnerships also include associated clinical progress milestones and sales-based payments to us, in addition to annual lease payments.

In order to evaluate how our sales are trending across key markets, as well as the contribution of program-related revenue from our SPL partnerships, we separately analyze revenue derived from our cell therapy customers and drug discovery customers, as well as the performance-based milestone revenues we recognize under our SPL partnerships. Cell therapy revenues include primarily revenue from instruments sold, annual license fees for instruments under lease, and sales of our proprietary disposables. Drug discovery revenue includes primarily revenue from instruments sold, sales of our proprietary disposables and, occasionally, instruments leased. Program-related revenues include clinical progress milestone and sales-based revenues derived from SPL agreements. Milestone revenues are recognized when a customer achieves the associated milestone event. To date, all program-related revenue has consisted entirely of pre-commercial milestone revenue.

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The following table provides details regarding the sources of our revenue for the periods presented:

	Three Months Ended
	March 31,				Change
	2023		2022		Amount		%
(in thousands, except percentages)
Cell therapy	$	5,975	$	7,416	$	(1,442)	(19%)
Drug discovery		1,797		2,167		(369)	(17%)
Program-related		804		2,004		(1,200)	(60%)
Total revenue	$	8,576	$	11,587	$	(3,011)	(26%)

Total revenue for the three months ended March 31, 2023 was $8.6 million, a decrease of $3.0 million, or 26%, compared to revenue of $11.6 million during the three months ended March 31, 2022.

Our overall decrease in revenue was primarily driven by revenue decreases in the cell therapy market and program-related revenues. In the cell therapy market, revenue from instrument sales and disposable sales decreased by $0.8 million and $0.7 million, respectively, in part due to the timing of purchases from customers. The $1.2 million decrease in program-related revenues resulted from expected variability of milestone revenues from period to period given the small number of individual triggering events which currently generate this portion of revenue. We expect program-related revenue to experience variability for some time, although we anticipate that this variability may moderate as the volume of SPLs and associated milestones grow. The $0.4 million decrease in the drug discovery market was primarily driven by a $0.7 million decrease in disposable sales, partially offset by a $0.3 million increase in instrument sales.

We expect total revenue to increase over time as our customers’ programs advance and our markets grow, resulting in additional instrument sales and leases and disposable sales and as the percentage of our installed base that are under cell therapy license agreements increases. We expect revenue from disposable and instrument sales and instrument licenses to cell therapy customers to continue to grow as those customers advance their preclinical pipeline programs into clinical development and move their existing drug development programs into later-stage clinical trials and, potentially, into commercialization. In addition, we expect new customers to continue to emerge and contribute to these revenues, based on the underlying growth in the cell therapy pipeline among companies in this market, the extent to which capital is available to support such companies, and in particular the switch by some cell therapy companies away from viral to non-viral approaches. We expect, however, that our revenue will fluctuate from period to period due to the timing of securing product sales and licenses, the inherently uncertain nature of the timing of our partners’ achievements of clinical progress and our dependence on the program decisions of our partners.

Cost of Goods Sold and Gross Profit

Cost of goods sold primarily consists of costs for instrument and processing assembly components, contract manufacturer costs, salaries, overhead and other direct costs related to sales recognized as revenue in the period. Cost of goods sold associated with instrument lease revenue consists of leased equipment depreciation. Gross profit is calculated as revenue less cost of goods sold. Gross profit margin is gross profit expressed as a percentage of revenue.

Our gross profit in future periods will depend on a variety of factors, including sales mix among instruments, disposables and milestones, the specific mix among types of instruments or disposables, the proportion of revenues associated with instrument leases as opposed to sales, changes in the costs to produce our various products, the launch of new products or changes in existing products, our cost structure for manufacturing including changes in production volumes, and the pricing of our products which may be impacted by market conditions.

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During the three months ended March 31, 2023, gross margin was 88%, compared to 91% in the same period of 2022. The decrease in gross margin was principally due to changes in the overall mix of product revenues. We price our instruments at a premium given what we believe to be the broad benefits of our platform, and the limited availability of alternative, clinically validated non-viral delivery approaches. Instrument pricing also depends upon the customer’s specific market. However, the market for non-viral delivery is highly competitive, and introduction of a GMP-grade platform by a competitor that delivers similar performance across a similar diversity of cell types could negatively impact our business and lead to increased price pressure that negatively impacts our gross margins.

	Three Months Ended March 31,				Change
	2023		2022		Amount		%
(in thousands, except percentages)
Cost of goods sold	$	1,000	$	1,063	$	(63)	(6)%
Gross profit	$	7,577	$	10,525	$	(2,949)	(28)%
Gross margin		88%		91%

Cost of goods sold decreased by $0.1 million, or 6%, for the three months ended March 31, 2023 compared to the three months ended March 31, 2022. The decrease was primarily driven by lower sales of instruments and disposables, partially offset by increased costs due to initial scale-up of our in-house manufacturing processing assemblies. We expect initial higher in-house manufacturing costs due to lower utilization. These manufacturing costs will decrease as we improve utilization, gain experience and implement automation.

Gross profit decreased for the three months ended March 31, 2023 compared to the three months ended March 31, 2022. The decrease was primarily driven by decreased revenue from instrument and disposable sales and decreased program-related revenue as well as increased manufacturing costs.

We expect that our cost of goods sold will generally increase or decrease as our instrument and disposables revenue increases or decreases. We expect our gross margin to benefit from realization of program-related revenue from our SPL agreements, to the extent that such revenue grows to be a significant proportion of overall revenues, as there is no cost of goods sold associated with such revenue. However, realization and timing of these potential milestone revenues is uncertain.

Operating Expenses

Research and Development

	Three Months Ended March 31,				Change
	2023		2022		Amount		%
(in thousands, except percentages)
Research and development	$	6,047	$	3,765		$2,281	61%

Research and development expenses consist primarily of costs incurred for our research activities related to advancing our technology and development of applications for our technology, including research into specific applications and associated data development, process development, product development (e.g., development of instruments and disposables, including hardware and software engineering) and design and other costs not directly charged to inventory or cost of goods sold.

These expenses principally include employee-related costs, such as salaries, benefits, incentive compensation, stock-based compensation, and travel, as well as consultant services, facilities, and laboratory supplies and materials. These expenses are exclusive of depreciation and amortization. We expense research and development costs as incurred in the period in which the underlying activity is undertaken.

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Research and development expenses increased by $2.3 million, or 61%, for the three months ended March 31, 2023 compared to the three months ended March 31, 2022. The increase was primarily driven by a $0.7 million increase in compensation expenses as a result of increases in headcount, a $0.4 million increase in stock-based compensation, a $0.3 million increase in occupancy expenses, a $0.3 million increase in lab expense and new product development, and a $0.2 million increase in professional service fees relating to new product and regulatory consultants.

We believe that our continued investment in research and development is essential to our long-term competitive position. We expect to continue to incur substantial research and development expenses as we invest in research and development to support our customers, develop new uses for our existing technology and develop improved and/or new offerings for our customers and partners. As a result, we expect that our research and development expenses will continue to increase in absolute dollars in future periods and vary from period to period as a percentage of revenue.

Sales and Marketing

	Three Months Ended March 31,				Change
	2023		2022		Amount		%
(in thousands, except percentages)
Sales and marketing	$	6,296	$	3,839	$	2,457	64%

Our sales and marketing expenses consist primarily of salaries, commissions and other variable compensation, benefits, stock-based compensation and travel costs for employees within our commercial sales and marketing functions, as well as third-party costs associated with our marketing activities. These expenses are exclusive of depreciation and amortization.

Sales and marketing expenses increased by $2.5 million, or 64%, for the three months ended March 31, 2023 compared to the three months ended March 31, 2022. The increase was primarily driven by a $1.3 million increase in compensation expenses as a result of increases in headcount, a $0.8 million increase in marketing and travel expenses, and a $0.2 million increase in stock-based compensation.

We expect our recurring sales and marketing expenses to increase in future periods as we expand our commercial sales, marketing and business development teams, product offerings, expand our collaboration efforts, increase our presence globally, and increase marketing activities to drive awareness and adoption of our products.

General and Administrative

	Three Months Ended March 31,				Change
	2023		2022		Amount		%
(in thousands, except percentages)
General and administrative	$	7,499	$	6,633	$	866	13%

General and administrative expenses primarily consist of salaries, benefits, stock-based compensation and travel costs for employees in our executive, accounting and finance, legal, corporate development, human resources, information systems and office administration functions as well as professional services fees, such as consulting, audit, tax and legal fees, general corporate costs, facilities and allocated overhead expenses and public company fees associated with being a Nasdaq and AIM listed public company such as director fees, U.K. Nominated Adviser and broker fees, investor relations consultants and insurance costs. These expenses are exclusive of depreciation and amortization.

General and administrative expense increased by $0.9 million, or 13%, for the three months ended March 31, 2023 compared to the three months ended March 31, 2022. The increase was primarily driven by a $0.8 million increase in strategic consulting expenses, a $0.3 million increase in compensation expense associated with headcount, and a $0.2 million increase in stock-based compensation, partially offset by a $0.4 million decrease in legal and public company fees.

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We expect that our general and administrative expenses will continue to increase in absolute dollars in future periods, primarily due to increased headcount to support anticipated growth in the business and due to incremental costs associated with operating as a public company listed on a U.S. exchange, including insurance (particularly directors and officers insurance), costs to comply with the rules and regulations applicable to companies listed on a U.S. securities exchange and costs related to compliance and reporting obligations pursuant to the rules and regulations of the SEC and stock exchange listing standards, investor relations and professional services. We expect these expenses to vary from period to period as a percentage of revenue.

Depreciation and Amortization

Depreciation expense consists of the depreciation of property and equipment used actively in the business, primarily by research and development activities. Amortization expense includes the amortization of intangible assets over their respective useful lives.

	Three Months Ended March 31,				Change
	2023		2022		Amount		%
(in thousands, except percentages)
Depreciation and amortization	$	912	$	447	$	465	104%

Depreciation and amortization expense increased by $0.5 million, or 104%, for the three months ended March 31, 2023, compared to the three months ended March 31, 2022. The increase was primarily driven by increases in leasehold improvements and purchases in laboratory equipment.

Interest and Other Income

	Three Months Ended March 31,				Change
	2023		2022		Amount		%
(in thousands, except percentages)
Interest income	$	2,296		92	$	2,204	2401%

Interest income represents interest on our cash balances and short-term investments, which increased by $2.2 million for the three months ended March 31, 2023. The increase was driven by increases in interest rates and a higher weighted average balance of interest-bearing securities held during the three months ended March 31, 2023.

We did not incur any interest expense for the three months ended March 31, 2023 or 2022 as we had no indebtedness outstanding during those periods.

Liquidity and Capital Resources

Since our inception, we have experienced losses and negative cash flows from operations. For the three months ended March 31, 2023, we incurred a net loss of $10.9 million. As of March 31, 2023, we had an accumulated deficit of $148.8 million. We have funded our operations primarily with proceeds from sales of common stock, including our initial public offering of common stock in the United States (the “IPO”) in 2021, as well as revenues associated with sales and licenses of our products to customers. As of March 31, 2023, we had cash and cash equivalents and short-term investments of $224.7 million.

We expect to incur near-term operating losses as we continue to invest in expanding our business through growing our sales and marketing efforts, continued research and development, product development and expanding our product offerings. Based on our current business plan, we believe our existing cash and cash equivalents and short-term investments will enable us to fund our operating expenses and capital expenditure requirements for the foreseeable future.

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We have based this estimate on assumptions that may prove to be wrong, and we could utilize our available capital resources sooner than we expect. Our future funding requirements will depend on many factors, including:

• transaction and capital expenditures necessitated by strategic activities;

• market acceptance of our products;

• the cost and timing of establishing additional sales, marketing and distribution capabilities;

• the cost of our research and development activities and successful development of data supporting use of our products for new applications, and timely launch of new features and products;

• sales to existing and new customers and the progress of our SPL partners in developing their pipelines of product candidates;

• our ability to enter into additional SPL partnerships and licenses for clinical use of our platform in the future;

• changes in the amount of capital available to existing and emerging customers in our target markets;

• the effect of competing technological and market developments; and

• the level of our selling, general and administrative expenses.

If we are unable to execute on our business plan and adequately fund operations, or if our business plans require a level of spending in excess of cash resources, we will have to seek additional equity or debt financing. If additional financings are required from outside sources, we may not be able to raise such capital on terms acceptable to us or at all. To the extent that we raise additional capital through the sale of equity or debt securities, the ownership interest of our stockholders will be diluted, and the terms of these securities may include liquidation or other preferences that adversely affect the rights of our common stockholders. Debt financing, if available, may involve agreements that include covenants restricting our ability to take specific actions, such as incurring additional debt, selling or licensing our assets, making product acquisitions, making capital expenditures or declaring dividends. If we raise additional funds through collaboration and licensing arrangements with third parties, it may be necessary to relinquish some rights to our technologies or our products, or grant licenses on terms that are not favorable to us. If we are unable to raise additional capital when desired, we may have to delay development or commercialization of future products. We also may have to reduce marketing, customer support or other resources devoted to our existing products.

Cash Flows

The following table summarizes our uses and sources of cash for the periods presented:

	Three Months Ended
	March 31,
(in thousands)	2023		2022
Net cash provided by (used in):
Operating activities	$	(4,325)	$	(3,694)
Investing activities		29,637		194,797
Financing activities		1,457		893
Net increase in cash and cash equivalents	$	26,769	$	191,995

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Operating Activities

Net cash used in operating activities for the three months ended March 31, 2023 was $4.3 million, and consisted primarily of our net loss of $10.9 million, offset in part by net non-cash expenses of $2.5 million, including stock-based compensation of $3.3 million and depreciation and amortization expenses of $1.0 million, reduced by amortization of discounts on investments of $1.7 million. We also had net cash inflows of $3.9 million due to changes in our operating assets and liabilities. Net changes in our operating assets and liabilities consisted primarily of a decrease in account receivable of $3.4 million due to increased cash collections, an increase in accounts payable and accrued expenses of $1.2 million due to timing considerations, a decrease in tenant improvements allowance (“TIA”) receivable of $0.9 million, a decrease in prepaid expense and other current assets of $0.5 million, and a decrease in other assets of $0.4 million, partially offset by a $1.7 million increase in inventory and a $1.0 million increase in deferred revenue.

Net cash used in operating activities for the three months ended March 31, 2022 was $3.7 million, and consisted primarily of our net loss of $4.1 million, offset in part by net non-cash expenses of $3.0 million, including stock-based compensation of $2.5 million and depreciation and amortization expense of $0.5 million. We also had net cash inflows of $2.7 million due to net changes in our operating assets and liabilities. Net changes in our operating assets and liabilities consisted primarily of an increase in the net effect of our right-of-use assets and lease liabilities of $2.4 million and a $1.1 million decrease in other current assets, partially offset by a $2.1 million increase in TIA receivable, a $1.8 million increase in accounts receivable, a $1.4 million increase in inventory, a $0.7 million increase in other non-current assets and a $0.2 million increase in accounts payable and accrued expenses.

Investing Activities

Net cash provided by investing activities during the three months ended March 31, 2023 was $29.6 million, which was primarily attributable to maturities of short-term marketable securities of $89.0 million, partially offset by purchases of short-term marketable securities of $57.8 million and purchases of laboratory equipment of $1.6 million.

Net cash provided by investing activities during the three months ended March 31, 2022 was $194.8 million, which was primarily attributable to maturities of short-term marketable securities of $200.8 million, partially offset by purchases of property and equipment of $0.6 million and leasehold improvements of $5.5 million. Purchases and sales of short-term marketable securities are made as part of ordinary course investing activities in compliance with our investment policy which has as its primary objective preservation of principal.

Financing Activities

Net cash provided by financing activities during the three months ended March 31, 2023 and 2022 was $1.5 million and $0.9 million, respectively, which was attributable to the exercise of stock options.

Contractual Obligations and Commitments

Our contractual obligations and commitments as of March 31, 2023 consisted exclusively of operating lease obligations. In May 2021, we entered into an operating lease for new office, lab and warehouse/manufacturing space. The lease for the new facility consists of three phases, with Phase 1 having commenced in December 2021 and Phase 2 having commenced in the first quarter of 2022. Phase 3 is expected to begin in the second half of 2023. The lease term for all phases expires on August 31, 2035. We designed and constructed the leasehold improvements with the approval of the landlord. The lease provides that the landlord will reimburse us for $6.3 million in costs of leasehold improvement construction. As of March 31, 2023, we received TIA reimbursements of $5.2 million. The total incremental non-cancellable lease payments under the lease agreement are $29.6 million through the lease term. We expect to be able to fund our obligations under the new lease, both in the short term and in the long term, from cash on hand, short-term investments and operating cash flows.

In June 2022, we exercised our option to early terminate the remaining subleased office, laboratory, manufacturing and other spaces associated with our former headquarters facility, which terminations became effective in July and August 2022. In addition, our lease of space at the same location expired on June 7, 2022. The lease and subleases previously had expiration dates in October 2023.

25

We had no debt obligations as of March 31, 2023 and December 31, 2022.

Purchase orders or contracts for the purchase of supplies and other goods and services are based on our current procurement or development needs and are generally fulfilled by our vendors within short time horizons.

Critical Accounting Estimates

We have prepared our condensed consolidated financial statements in accordance with U.S. GAAP. Our preparation of these condensed consolidated financial statements requires us to make estimates, assumptions and judgments that affect the reported amounts of assets, liabilities, revenue, expenses and related disclosures. We evaluate our estimates and judgments on an ongoing basis. We base our estimates on historical experience and on various other factors that we believe are reasonable under the circumstances, the results of which form the basis for making judgments about the carrying value of assets and liabilities that are not readily apparent from other sources.

Actual results could therefore differ materially from these estimates under different assumptions or conditions.

There have been no material changes to our critical accounting policies and estimates from those disclosed in our consolidated financial statements and the related notes and other financial information included in the Annual Report on Form 10-K filed with SEC on March 15, 2023.

JOBS Act Accounting Election

We are an “emerging growth company,” (“EGC”), under the Jumpstart Our Business Startups Act of 2012, (the “JOBS Act”). Section 107 of the JOBS Act provides that an EGC can take advantage of the extended transition period provided in Section 7(a)(2)(B) of the Securities Act for complying with new or revised accounting standards. Thus, an EGC can delay the adoption of certain accounting standards until those standards would otherwise apply to private companies. We have elected to avail ourselves of the delayed adoption of new and revised accounting standards and, therefore, we will be subject to the same requirements to adopt new or revised accounting standards as private entities. We also intend to rely on other exemptions provided by the JOBS Act, including not being required to comply with the auditor attestation requirements of Section 404(b) of the Sarbanes-Oxley Act.

We will remain an EGC until the earliest of: (i) December 31, 2026, which is the last day of the fiscal year following the fifth anniversary of our initial public offering in the United States; (ii) the last day of the first fiscal year in which our annual gross revenue is $1.235 billion or more; (iii) the date on which we have, during the previous rolling three-year period, issued more than $1 billion in non-convertible debt securities; and (iv) the last day of the fiscal year in which the market value of our common stock held by non-affiliates exceeded $700 million as of June 30 of such fiscal year.

We are also a “smaller reporting company,” as defined by Rule 12b-2 of the Exchange Act. We may continue to be a smaller reporting company if either (i) the market value of our stock held by non-affiliates is less than $250 million as of the last business day of our second fiscal quarter or (ii) our annual revenue is less than $100 million during the most recently completed fiscal year and the market value of our stock held by non-affiliates is less than $700 million as of the last business day of our second fiscal quarter. If we are a smaller reporting company at the time we cease to be an emerging growth company, we may continue to rely on exemptions from certain disclosure requirements that are available to smaller reporting companies.

Recent Accounting Pronouncements

A description of recently issued accounting pronouncements that may potentially impact our financial position, results of operations or cash flows is disclosed in Note 2 to our condensed consolidated financial statements included in this Quarterly Report on Form 10-Q.

26

Item 3. Quantitative and Qualitative Disclosures About Market Risk

Interest Rate Risk

We are exposed to market risk for changes in interest rates related primarily to balances of our financial instruments including cash and cash equivalents and short-term investments. The primary objective of our investment approach is to preserve principal and provide liquidity. As a result, a 10% change in the level of market interest rates would not be expected to have a material effect on our business, financial condition or results of operations.

As we do not currently have indebtedness we are not exposed to interest rate risk from increases in interest rates.

Foreign Currency Risk

We are exposed to financial risks as a result of exchange rate fluctuations between the U.S. Dollar and certain foreign currencies and the volatility of these rates. In the normal course of business, we earn revenue primarily denominated in U.S. Dollars as well as in Euros and British Pounds. We incur expenses primarily in U.S. Dollars as well as in Euros, British Pounds and other currencies. Our reporting currency is the U.S. Dollar. We hold our cash primarily in U.S. Dollars as well as in Euros and British Pounds. We do not expect that foreign currency gains or losses will have a material effect on our financial position or results of operations in the foreseeable future. We have not entered into any hedging arrangements with respect to foreign currency risk. As our international operations grow, we will continue to reassess our approach to managing risks relating to fluctuations in currency exchange rates.

Inflation Risk

During the last two years, inflation and changing prices have not had a material effect on our business. We are unable to predict whether inflation or changing prices will materially affect our business in the foreseeable future.

Item 4. Controls and Procedures

Evaluation of Disclosure Controls and Procedures

We carried out an evaluation, under the supervision and with the participation of management, including our Chief Executive Officer and Chief Financial Officer, of the effectiveness of our “disclosure controls and procedures” as defined in Rules 13a-15(e) and 15d-15(e) of the Securities Exchange Act of 1934, as amended (the “Exchange Act”). The term “disclosure controls and procedures,” as defined in Rules 13a-15(e) and 15d-15(e) under the Exchange Act, means controls and other procedures of a company that are designed to ensure that information required to be disclosed by a company in the reports that it files or submits under the Exchange Act is recorded, processed, summarized and reported, within the time periods specified in the SEC’s rules and forms. Disclosure controls and procedures include, without limitation, controls and procedures designed to ensure that information required to be disclosed by a company in the reports that it files or submits under the Exchange Act is accumulated and communicated to the company’s management, including its principal executive and principal financial officers, or persons performing similar functions, as appropriate to allow timely decisions regarding required disclosure.

Based on our evaluation, our Chief Executive Officer and Chief Financial Officer concluded that the design and operation of these disclosure controls and procedures were effective as of March 31, 2023 at the reasonable assurance level.

Changes in Internal Control over Financial Reporting

There were no changes in our internal control over financial reporting during the three months ended March 31, 2023 that have materially affected, or are reasonably likely to materially affect, our internal control over financial reporting.

27

Limitations on the Effectiveness of Controls

Control systems, no matter how well designed and operated, can provide only reasonable, not absolute, assurance that the control systems’ objectives are being met. Further, the design of any system of controls must reflect the fact that there are resource constraints, and the benefits of all controls must be considered relative to their costs. Because of the inherent limitations in all control systems, no evaluation of controls can provide absolute assurance that all control issues and instances of fraud, if any, within our company have been detected. These inherent limitations include the realities that judgments in decision-making can be faulty and that breakdowns can occur because of error or mistake. Control systems can also be circumvented by the individual acts of some persons, by collusion of two or more people, or by management override of the controls. The design of any system of controls is also based in part upon certain assumptions about the likelihood of future events, and there can be no assurance that any design will succeed in achieving its stated goals under all potential future conditions. Over time, controls may become inadequate because of changes in conditions or deterioration in the degree of compliance with policies or procedures.

PART II. OTHER INFORMATION

Item 1. Legal Proceedings.

From time to time, we may become involved in legal proceedings arising in the ordinary course of our business. We are not currently a party to any material legal proceedings, and we are not aware of any pending or threatened legal proceeding against us that we believe could have an adverse effect on our business, operating results or financial condition.

Item 1A. Risk Factors.

There have been no material changes to the risk factors set forth in the Annual Report on Form 10-K filed with the SEC on March 15, 2023. However, the risk factors described in this report and in the Annual Report on Form 10-K are not the only risks that we face. Additional risks and uncertainties that we are unaware of, or that we currently believe are not material, may also become important factors that adversely affect our business. If any such risks materialize, it could have a material adverse effect on our business, financial condition, results of operations and growth prospects and cause the trading price of our common stock to decline.

Item 2. Unregistered Sales of Equity Securities and Use of Proceeds.

(a) Sale of Unregistered Securities

None.

(b) Use of Proceeds

On August 3, 2021, we closed our IPO, in which we issued and sold 15,525,000 shares of common stock at a price to the public of $13.00 per share, inclusive of 2,025,000 shares sold pursuant to the full exercise of the underwriters’ option to purchase additional shares. The IPO generated gross proceeds to us of $201.8 million. We received net proceeds of $184.3 million after deducting aggregate underwriting commissions and offering expenses of $17.6 million. All of the shares of common stock issued and sold in the offering were registered under the Securities Act of 1933, as amended (“Securities Act”) pursuant to a registration statement on Form S-1 (File No. 333-257810), which was declared effective by the SEC on July 29, 2021. The joint book-running managers of the offering were Cowen and Company, LLC, Stifel, Nicolaus & Company, Incorporated and William Blair & Company, L.L.C.

In connection with our IPO, no payments were made by us to directors, officers or persons owning ten percent or more of our common stock or to their associates or to our affiliates.

Cash used since the IPO is described in the “Management’s Discussion and Analysis of Financial Condition and Results of Operations” section of this report and our other periodic reports filed with the SEC. As of the date of this report, there has been no material change in the planned use of proceeds from the IPO as described in the final prospectus for our IPO.

28

Item 3. Defaults Upon Senior Securities.

Not applicable.

Item 4. Mine Safety Disclosures.

Not applicable.

Item 5. Other Information.

As previously disclosed in our Current Report on Form 8-K filed on March 28, 2023, Ron Holtz, our former interim Chief Financial Officer, ceased serving as our principal financial officer as of March 27, 2023, upon the appointment of Douglas Swirsky as our Chief Financial Officer on that date.  Mr. Holtz continues as our EVP, Administration, but effective upon the filing of this report Mr. Holtz has ceased to be an executive officer of our company and is no longer an “officer” for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, and Rule 16a-1 thereunder.

29

Item 6. Exhibits.

The following exhibits are filed with this Quarterly Report on Form 10-Q:

		Incorporated by Reference
Exhibit Number	Description	Form	File No.	Exhibit	Filing Date
3.1	Amended and Restated Bylaws of the Registrant.	8-K	001-40674	3.1	August 4, 2021
3.2	Fifteenth Amended and Restated Certificate of Incorporation.	S-1	333-25781	3.1	July 26, 2021
10.1	Severance Agreement, dated March 27, 2023, by and between the registrant and Douglas J. Swirsky	8-K	001-40674	10.1	March 28, 2023
31.1	Certification of Principal Executive Officer Pursuant to Rules 13a-14(a) and 15d-14(a) under the Securities Exchange Act of 1934, as Adopted Pursuant to Section 302 of the Sarbanes-Oxley Act of 2002.
31.2	Certification of Principal Financial Officer Pursuant to Rules 13a-14(a) and 15d-14(a) under the Securities Exchange Act of 1934, as Adopted Pursuant to Section 302 of the Sarbanes-Oxley Act of 2002.
32.1*	Certification of Principal Executive Officer Pursuant to 18 U.S.C. Section 1350, as Adopted Pursuant to Section 906 of the Sarbanes-Oxley Act of 2002.
32.2*	Certification of Principal Financial Officer Pursuant to 18 U.S.C. Section 1350, as Adopted Pursuant to Section 906 of the Sarbanes-Oxley Act of 2002.
101.INS	Inline XBRL Instance Document.
101.SCH	XBRL Taxonomy Extension Schema Document
101.CAL	XBRL Taxonomy Extension Calculation Linkbase Document
101.DEF	XBRL Taxonomy Extension Definition Linkbase Document
101.LAB	XBRL Taxonomy Extension Label Linkbase Document
101.PRE	XBRL Taxonomy Extension Presentation Linkbase Document
104	Cover Page Interactive Data File (formatted as inline XBRL with applicable taxonomy extension information contained in Exhibits 101.SCH, 101.CAL, 101.DEF, 101.LAB and 101.PRE).

* This exhibit shall not be deemed “filed” for purposes of Section 18 of the Exchange Act or otherwise subject to the liabilities of that section, nor shall it be deemed incorporated by reference in any filing under the Securities Act of 1933 or the Exchange Act of 1934, whether made before or after the date hereof and irrespective of any general incorporation language in such filing.

30

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized.

	MaxCyte, Inc.
Date: May 10, 2023	By:	/s/ Douglas Doerfler
	Name:	Douglas Doerfler
	Title:	President and Chief Executive Officer
		(On Behalf of the Registrant)
Date: May 10, 2023	By:	/s/ Douglas Swirsky
	Name:	Douglas Swirsky
	Title:	Chief Financial Officer (Principal Financial Officer)

31

EX-31.1

EXHIBIT 31.1

CERTIFICATION PURSUANT TO

RULES 13a-14(a) AND 15d-14(a) UNDER THE SECURITIES EXCHANGE ACT OF 1934,

AS ADOPTED PURSUANT TO SECTION 302 OF THE SARBANES-OXLEY ACT OF 2002

I, Douglas Doerfler, certify that:

1. I have reviewed this Quarterly Report on Form 10-Q of MaxCyte, Inc.;

2. Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report;

3. Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in all material respects the financial condition, results of operations and cash flows of the registrant as of, and for, the periods presented in this report;

4. The registrant’s other certifying officer(s) and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 13a-15(r) and 15d-15(r)) for the registrant and have:

(a) Designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure that material information relating to the registrant, including its consolidated subsidiaries, is made known to us by others within those entities, particularly during the period in which this report is being prepared;

(b) Designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under our supervision, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted accounting principles;

(c) Evaluated the effectiveness of the registrant’s disclosure controls and procedures and presented in this report our conclusions about the effectiveness of the disclosure controls and procedures, as of the end of the period covered by this report based on such evaluation; and

(d) Disclosed in this report any change in the registrant’s internal control over financial reporting that occurred during the registrant’s most recent fiscal quarter (the registrant’s fourth fiscal quarter in the case of an annual report) that has materially affected, or is reasonably likely to materially affect, the registrant’s internal control over financial reporting; and

5. The registrant’s other certifying officer(s) and I have disclosed, based on our most recent evaluation of internal control over financial reporting, to the registrant’s auditors and the audit committee of the registrant’s board of directors (or persons performing the equivalent functions):

(a) All significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely affect the registrant’s ability to record, process, summarize and report financial information; and

(b) Any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant’s internal control over financial reporting.

Date: May 10, 2023	By:	/s/ Douglas Doerfler
	Name:	Douglas Doerfler
	Title:	President and Chief Executive Officer
		(Principal Executive Officer)

EX-31.2

EXHIBIT 31.2

CERTIFICATION PURSUANT TO

RULES 13a-14(a) AND 15d-14(a) UNDER THE SECURITIES EXCHANGE ACT OF 1934,

AS ADOPTED PURSUANT TO SECTION 302 OF THE SARBANES-OXLEY ACT OF 2002

I, Douglas Swirsky, certify that:

1. I have reviewed this Quarterly Report on Form 10-Q of MaxCyte, Inc.;

2. Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report;

3. Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in all material respects the financial condition, results of operations and cash flows of the registrant as of, and for, the periods presented in this report;

4. The registrant's other certifying officer(s) and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 13a-15(r) and 15d-15(r)) for the registrant and have:

(a) Designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure that material information relating to the registrant, including its consolidated subsidiaries, is made known to us by others within those entities, particularly during the period in which this report is being prepared;

(b) Designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under our supervision, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted accounting principles;

(c) Evaluated the effectiveness of the registrant's disclosure controls and procedures and presented in this report our conclusions about the effectiveness of the disclosure controls and procedures, as of the end of the period covered by this report based on such evaluation; and

(d) Disclosed in this report any change in the registrant's internal control over financial reporting that occurred during the registrant's most recent fiscal quarter (the registrant's fourth fiscal quarter in the case of an annual report) that has materially affected, or is reasonably likely to materially affect, the registrant's internal control over financial reporting; and

5. The registrant's other certifying officer(s) and I have disclosed, based on our most recent evaluation of internal control over financial reporting, to the registrant's auditors and the audit committee of the registrant's board of directors (or persons performing the equivalent functions):

(a) All significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely affect the registrant's ability to record, process, summarize and report financial information; and

(b) Any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant's internal control over financial reporting.

Date: May 10, 2023	By:	/s/ Douglas Swirsky
	Name:	Douglas Swirsky
	Title:	Chief Financial Officer (Principal Financial Officer)

EX-32.1

EXHIBIT 32.1

CERTIFICATION OF PRINCIPAL EXECUTIVE OFFICER

PURSUANT TO 18 U.S.C. SECTION 1350,

AS ADOPTED PURSUANT TO SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002

In connection with the Quarterly Report of MaxCyte, Inc. (the “Company”) on Form 10-Q for the period ended March 31, 2023 as filed with the Securities and Exchange Commission on the date hereof (the “Report”), I certify, pursuant to 18 U.S.C. § 1350, as adopted pursuant to § 906 of the Sarbanes-Oxley Act of 2002, that:

(1) The Report fully complies with the requirements of section 13(a) or 15(d) of the Securities Exchange Act of 1934, as amended; and

(2) The information contained in the Report fairly presents, in all material respects, the financial condition and result of operations of the Company.

Date: May 10, 2023	By:	/s/ Douglas Doerfler
	Name:	Douglas Doerfler
	Title:	President and Chief Executive Officer
		(Principal Executive Officer)

EX-32.2

EXHIBIT 32.2

CERTIFICATION OF PRINCIPAL FINANCIAL OFFICER

PURSUANT TO 18 U.S.C. SECTION 1350,

AS ADOPTED PURSUANT TO SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002

In connection with the Quarterly Report of MaxCyte, Inc. (the “Company”) on Form 10-Q for the period ended March 31, 2023 as filed with the Securities and Exchange Commission on the date hereof (the “Report”), I certify, pursuant to 18 U.S.C. § 1350, as adopted pursuant to § 906 of the Sarbanes-Oxley Act of 2002, that:

(1) The Report fully complies with the requirements of section 13(a) or 15(d) of the Securities Exchange Act of 1934, as amended; and

(2) The information contained in the Report fairly presents, in all material respects, the financial condition and result of operations of the Company.

Date: May 10, 2023	By:	/s/ Douglas Swirsky
	Name:	Douglas Swirsky
	Title:	Chief Financial Officer (Principal Financial Officer)

XML

Document and Entity Information - shares	3 Months Ended
	Mar. 31, 2023	May 02, 2023
Document and Entity Information [Abstract]
Document Type	10-Q
Document Quarterly Report	true
Document Transition Report	false
Document Period End Date	Mar. 31, 2023
Entity File Number	001-40674
Entity Registrant Name	MaxCyte, Inc.
Entity Incorporation, State or Country Code	DE
Entity Tax Identification Number	52-2210438
Entity Address, Address Line One	9713 Key West Avenue
Entity Address, Address Line Two	Suite 400
Entity Address, City or Town	Rockville
Entity Address State Or Province	MD
Entity Address, Postal Zip Code	20850
City Area Code	301
Local Phone Number	944-1700
Title of 12(b) Security	Common stock, par value $0.01 per share
Trading Symbol	MXCT
Security Exchange Name	NASDAQ
Entity Current Reporting Status	Yes
Entity Interactive Data Current	Yes
Entity Filer Category	Non-accelerated Filer
Entity Small Business	true
Entity Emerging Growth Company	true
Entity Ex Transition Period	false
Entity Shell Company	false
Entity Common Stock, Shares Outstanding		103,050,899
Entity Central Index Key	0001287098
Current Fiscal Year End Date	--12-31
Document Fiscal Year Focus	2023
Document Fiscal Period Focus	Q1
Amendment Flag	false

XML

Condensed Consolidated Balance Sheets - USD ($)	Mar. 31, 2023	Dec. 31, 2022
Current assets:
Cash and cash equivalents	$ 37,833,400	$ 11,064,700
Short-term investments, at amortized cost	186,819,300	216,274,900
Accounts receivable	8,294,800	11,654,600
Accounts receivable - TIA (Note 7)	996,600	1,912,400
Inventory	10,264,900	8,580,800
Prepaid expenses and other current assets	2,230,600	2,778,800
Total current assets	246,439,600	252,266,200
Property and equipment, net	24,947,900	23,724,700
Right-of-use asset - operating leases	9,757,600	9,853,500
Other assets	399,300	809,000
Total assets	281,544,400	286,653,400
Current liabilities:
Accounts payable	3,502,100	531,800
Accrued expenses and other	6,912,900	8,025,300
Operating lease liability, current	475,200	156,800
Deferred revenue, current portion	5,749,200	6,712,600
Total current liabilities	16,639,400	15,426,500
Operating lease liability, net of current portion	15,777,200	15,938,100
Other liabilities	1,309,000	1,321,600
Total liabilities	33,725,600	32,686,200
Commitments and contingencies (Note 7)
Stockholders' equity
Preferred stock, $0.01 par value; 5,000,000 shares authorized and no shares issued and outstanding at March 31, 2023 and December 31, 2022
Common stock, $0.01 par value; 400,000,000 shares authorized, 102,904,745 and 102,397,913 shares issued and outstanding at March 31, 2023 and December 31, 2022, respectively	1,029,100	1,024,000
Additional paid-in capital	395,546,600	390,818,500
Accumulated deficit	(148,756,900)	(137,875,300)
Total stockholders' equity	247,818,800	253,967,200
Total liabilities and stockholders' equity	$ 281,544,400	$ 286,653,400

XML

Condensed Consolidated Balance Sheets (Parenthetical) - $ / shares	Mar. 31, 2023	Dec. 31, 2022
Condensed Consolidated Balance Sheets
Preferred stock, par value (in dollars per share)	$ 0.01	$ 0.01
Preferred stock, authorized (in shares)	5,000,000	5,000,000
Preferred stock, issued (in shares)	0	0
Preferred stock, outstanding (in shares)	0	0
Common stock, par value (in dollars per share)	$ 0.01	$ 0.01
Common stock, authorized (in shares)	400,000,000	400,000,000
Common stock, issued (in shares)	102,904,745	102,397,913
Common stock, outstanding (in shares)	102,904,745	102,397,913

XML

Unaudited Condensed Consolidated Statements of Operations - USD ($)	3 Months Ended
	Mar. 31, 2023	Mar. 31, 2022
Unaudited Condensed Consolidated Statements of Operations
Revenue	$ 8,576,300	$ 11,587,300
Cost of goods sold	999,800	1,062,600
Gross profit	7,576,500	10,524,700
Operating expenses:
Research and development	6,046,500	3,765,300
Sales and marketing	6,296,100	3,838,700
General and administrative	7,498,900	6,632,500
Depreciation and amortization	912,200	447,300
Total operating expenses	20,753,700	14,683,800
Operating loss	(13,177,200)	(4,159,100)
Other income:
Interest income	2,295,600	91,800
Total other income	2,295,600	91,800
Net loss	$ (10,881,600)	$ (4,067,300)
Basic net loss per share	$ (0.11)	$ (0.04)
Diluted net loss per share	$ (0.11)	$ (0.04)
Weighted average shares outstanding, basic	102,846,036	101,305,943
Weighted average shares outstanding, diluted	102,846,036	101,305,943

XML

Unaudited Condensed Consolidated Statements of Changes in Stockholders' Equity - USD ($)	Common Stock	Additional Paid-in Capital	Accumulated Deficit	Total
Balances, at Beginning of period at Dec. 31, 2021	$ 1,012,000	$ 376,189,600	$ (114,304,500)	$ 262,897,100
Balances, at Beginning of period, Shares at Dec. 31, 2021	101,202,705
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Stock-based compensation expense		2,462,400		2,462,400
Exercise of stock options	$ 3,100	889,500		892,600
Exercise of stock options, shares	307,187
Net loss			(4,067,300)	(4,067,300)
Balances, at end of period at Mar. 31, 2022	$ 1,015,100	379,541,500	(118,371,800)	262,184,800
Balances, at end of period, Shares at Mar. 31, 2022	101,509,892
Balances, at Beginning of period at Dec. 31, 2021	$ 1,012,000	376,189,600	(114,304,500)	$ 262,897,100
Balances, at Beginning of period, Shares at Dec. 31, 2021	101,202,705
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of common stock, net of issuance costs, shares				1,195,208
Balances, at end of period at Dec. 31, 2022	$ 1,024,000	390,818,500	(137,875,300)	$ 253,967,200
Balances, at end of period, Shares at Dec. 31, 2022	102,397,913
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of common stock, net of issuance costs, shares				506,832
Stock-based compensation expense		3,276,600		$ 3,276,600
Exercise of stock options	$ 5,100	1,451,500		1,456,600
Exercise of stock options, shares	506,832
Net loss			(10,881,600)	(10,881,600)
Balances, at end of period at Mar. 31, 2023	$ 1,029,100	$ 395,546,600	$ (148,756,900)	$ 247,818,800
Balances, at end of period, Shares at Mar. 31, 2023	102,904,745

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Unaudited Condensed Consolidated Statements of Cash Flows - USD ($)	3 Months Ended
	Mar. 31, 2023	Mar. 31, 2022
Cash flows from operating activities:
Net loss	$ (10,881,600)	$ (4,067,300)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization	961,700	487,400
Net book value of consigned equipment sold	16,800	32,800
Stock-based compensation	3,276,600	2,462,400
Amortization of discounts on short-term investments	(1,730,100)	(33,200)
Changes in operating assets and liabilities:
Accounts receivable	3,359,800	(1,750,800)
Accounts receivable - TIA	915,800	(2,119,200)
Inventory	(1,706,000)	(1,377,000)
Prepaid expense and other current assets	548,200	1,117,200
Right of use asset - operating leases	95,900	(5,212,600)
Other assets	409,700	(738,200)
Accounts payable, accrued expenses and other	1,227,000	(150,500)
Operating lease liability	157,500	7,569,000
Deferred revenue	(963,400)	84,900
Other liabilities	(12,600)	900
Net cash used in operating activities	(4,324,700)	(3,694,200)
Cash flows from investing activities:
Purchases of short-term investments	(57,814,300)
Maturities of short-term investments	89,000,000	200,796,000
Purchases of property and equipment	(1,558,000)	(5,999,500)
Proceeds from sale of equipment	9,100
Net cash provided by investing activities	29,636,800	194,796,500
Cash flows from financing activities:
Proceeds from exercise of stock options	1,456,600	892,600
Net cash provided by financing activities	1,456,600	892,600
Net increase in cash and cash equivalents	26,768,700	191,994,900
Cash and cash equivalents, beginning of year	11,064,700	47,782,400
Cash and cash equivalents, end of year	37,833,400	239,777,300
Supplemental disclosure of non-cash investing and financing activities:
Property and equipment purchases included in accounts payable	$ 630,900	$ 43,200

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Organization and Description of Business

3 Months Ended

Mar. 31, 2023

Organization and Description of Business

Organization and Description of Business

1.   Organization and Description of Business

MaxCyte, Inc. (the “Company” or “MaxCyte”) was incorporated as a majority owned subsidiary of EntreMed, Inc. (“EntreMed”) on July 31, 1998, under the laws and provisions of the state of Delaware and commenced operations on July 1, 1999. In November 2002, MaxCyte was recapitalized and EntreMed was no longer deemed to control the Company.

MaxCyte is a global life sciences company focused on advancing the discovery, development and commercialization of next-generation cell therapies. MaxCyte leverages its proprietary cell engineering technology platform to enable the programs of its biotechnology and pharmaceutical company customers who are engaged in cell therapy, including gene editing and immuno-oncology, as well as in drug discovery and development and biomanufacturing. The Company licenses and sells its instruments and technology and sells its consumables to developers of cell therapies and to pharmaceutical and biotechnology companies for use in drug discovery and development and biomanufacturing.

The Company’s registration statement on Form S-1 related to its initial public offering of common stock in the United States (the “IPO”) was declared effective on July 29, 2021, and the Company’s common stock began trading on the Nasdaq Global Select Market on July 30, 2021. On August 3, 2021, the Company issued and sold 15,525,000 shares of common stock in the IPO at a price to the public of $13.00 per share, inclusive of 2,025,000 shares issued pursuant to the full exercise of the underwriters’ option to purchase additional shares. The IPO generated gross proceeds to the Company of $201.8 million. The Company received aggregate net proceeds of $184.3 million from the IPO after deducting aggregate underwriting commissions and offering costs of $17.6 million.

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Summary of Significant Accounting Policies

3 Months Ended

Mar. 31, 2023

Summary of Significant Accounting Policies

Summary of Significant Accounting Policies

2.    Summary of Significant Accounting Policies

Basis of Presentation

The accompanying unaudited condensed consolidated interim financial statements have been prepared in accordance with accounting principles generally accepted in the United States of America (“U.S. GAAP”) for interim financial information and pursuant to the instructions to Form 10-Q and Article 10 of Regulation S-X of the United States Securities and Exchange Commission (the “SEC”). In the Company’s opinion, the accompanying unaudited condensed consolidated financial statements include all adjustments, consisting of normal recurring adjustments, which are necessary to present fairly the financial position, results of operations, and cash flows as of and for the periods presented. The condensed consolidated balance sheet at December 31, 2022 has been derived from audited consolidated financial statements as of that date. The unaudited condensed consolidated results of operations are not necessarily indicative of the results that may occur for the full fiscal year or any other future year or period. Certain information and footnotes disclosure normally included in financial statements prepared in accordance with U.S. GAAP have been omitted pursuant to instructions, rules, and regulations prescribed by the SEC. The Company believes that the disclosures provided herein are adequate to make the information presented not misleading when these unaudited interim condensed consolidated financial statements are read in conjunction with the audited consolidated financial statements and notes included in the Company’s Annual Report on Form 10-K filed with the SEC on March 15, 2023.

Significant Accounting Policies

The Company’s significant accounting policies are disclosed in the footnotes to its audited consolidated financial statements for the year ended December 31, 2022 included in its Annual Report on Form 10-K and have not materially changed during the three months ended March 31, 2023.

Basis of Consolidation

The consolidated financial statements include the accounts of the Company and its wholly-owned subsidiary. All significant intercompany balances have been eliminated in consolidation.

Concentration of Risk

The Company maintains its cash and cash equivalents with two financial institutions that management believes to be of high credit quality. At times the Company’s cash balances may exceed federally insured limits and cash may also be deposited in foreign bank accounts that are not covered by federal deposit insurance. The Company does not believe that this results in any significant credit risk beyond the normal credit risk associated with commercial banking relationships.

Significant customers are those that accounted for 10% or more of the Company’s total revenue for the period or accounts receivable as of the end of a reporting period. During the three months ended March 31, 2023, two customers represented 23% and 11% of revenue, respectively. During the three months ended March 31, 2022, one customer represented 33% of revenue. As of March 31, 2023, two customers accounted for 23% and 12% of accounts receivable, respectively. As of December 31, 2022, one customer accounted for 14% of accounts receivable.

Certain components included in the Company’s products are obtained from a single source or a limited group of suppliers. During the three months ended March 31, 2023 and 2022, the Company purchased 60% and 39%, respectively, of its inventory from one supplier. As of March 31, 2023, amounts payable to one supplier totaled 21% of total accounts payable. At December 31, 2022, amounts payable to two suppliers totaled 34% of total accounts payable.

Accounts Receivable

Accounts receivable are reduced by an allowance for doubtful accounts, if needed. The Company determined that no allowance was necessary at March 31, 2023 or December 31, 2022.

Foreign Currency

The Company’s functional currency is the US dollar; transactions denominated in foreign currencies are subject to currency risk. The Company recognized $6,100 in foreign currency transaction gains and $23,200 in foreign currency transaction losses for the three months ended March 31, 2023 and 2022, respectively.

Leases

For transactions in which the Company is the lessee, at the inception of a contract, the Company determines if the arrangement is, or contains, a lease. See Note 7 for additional details about leases under which the Company is the lessee.

All transactions in which the Company is the lessor are short-term (one year or less) and have been classified as operating leases. All leases require upfront payments covering the full period of the lease and thus, there are no future payments expected to be received from existing leases. See Note 3 for details on revenue recognition related to lease agreements.

Loss Per Share

Basic loss per share is computed by dividing net loss available to common stockholders by the weighted average number of shares of common stock outstanding during the period.

For periods of net income, and when the effects are not anti-dilutive, diluted earnings per share is computed by dividing net income available to common stockholders by the weighted-average number of shares outstanding plus the impact of all potential dilutive common shares, consisting primarily of common stock options and restricted stock units, and in the prior year periods stock purchase warrants, using the treasury stock method.

For periods of net loss, diluted loss per share is calculated similarly to basic loss per share because the impact of all dilutive potential common shares is anti-dilutive. The number of anti-dilutive shares excluded from the computation of diluted loss per share, consisting of shares underlying stock options and restricted stock units, was 17.1 million for the three months ended March 31, 2023 and 15.1 million for the three months ended March 31, 2022.

Recent Accounting Pronouncements

New Accounting Pronouncements Adopted

In June 2016, the Financial Accounting Standards Board (“FASB”) issued guidance with respect to measuring credit losses on financial instruments, including trade receivables. The guidance eliminates the probable initial recognition threshold that was previously required prior to recognizing a credit loss on financial instruments. The credit loss estimate can now reflect an entity’s current estimate of all future expected credit losses. Under the previous guidance, an entity only considered past events and current conditions. The current guidance is effective for fiscal years beginning after December 15, 2022, including interim periods within those fiscal years. The adoption of certain amendments of this guidance must be applied on a modified retrospective basis and the adoption of the remaining amendments must be applied on a prospective basis. The Company adopted this new accounting pronouncement effective on January 1, 2023, and the adoption did not have a material impact on its consolidated financial statements.

The Company has evaluated all other issued and unadopted Accounting Standards Updates and believes the adoption of these standards will not have a material impact on its results of operations, financial position, or cash flows.

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Revenue

3 Months Ended

Mar. 31, 2023

Revenue

Revenue

3.    Revenue

Revenue is principally from the sale of instruments and processing assemblies, and extended warranties and the lease of instruments, which lease agreements also include customer-specific milestone payments. In some arrangements, products and services have been sold together representing distinct performance obligations. In these arrangements the Company allocates the sale price to the various performance obligations in the arrangement on a relative selling price basis. Under this basis, the Company determines the estimated selling price of each performance obligation in a manner that is consistent with that used to determine the price to sell the deliverable on a standalone basis.

Revenue is recognized at the time control is transferred to the customer and the performance obligation is satisfied. Revenue from the sale of instruments and processing assemblies is generally recognized at the time of shipment to the customer, provided that no significant vendor obligations remain and collectability is reasonably assured. Revenue from equipment leases is recognized ratably over the contractual term of the lease agreement and when specific milestones are achieved by a customer. Licensing fee revenue is recognized ratably over the license period. Revenue from fees for research services is recognized when services have been provided.

Disaggregation of Revenue

The following table depicts the disaggregation of revenue by type of contract:

	Three months ended March 31, 2023
	Revenue from		Revenue
	Contracts		from
	with		Lease		Total
	Customers		Elements		Revenue
Product sales	$	4,789,700	$	—	$	4,789,700
Lease elements		—		3,612,800		3,612,800
Other		173,800		—		173,800
Total	$	4,963,500	$	3,612,800	$	8,576,300

	Three months ended March 31, 2022
	Revenue from		Revenue
	Contracts		from
	with		Lease		Total
	Customers		Elements		Revenue
Product sales	$	6,567,600	$	—	$	6,567,600
Lease elements		—		4,730,000		4,730,000
Other		289,700		—		289,700
Total	$	6,857,300	$	4,730,000	$	11,587,300

Additional Disclosures Relating to Revenue from Contracts with Customers

Deferred revenue represents payments received for performance obligations not yet satisfied and is presented as current or long-term in the accompanying condensed consolidated balance sheets based on the expected timing and satisfaction of the underlying goods or services. Deferred revenue was $6.1 million and $7.0 million as of March 31, 2023 and December 31, 2022, respectively. During the three months ended March 31, 2023 and 2022, the Company recognized $2.6 million and $2.6 million, respectively, of revenue that was included in deferred revenue at the beginning of such periods.

Remaining contract consideration for which revenue has not been recognized due to unsatisfied performance obligations with a duration greater than one year at March 31, 2023 was $405,200, of which the Company expects to recognize $94,700 in one year or less, $94,700 in one to two years, $47,300 in two to three years, and $168,500 thereafter.

For the three months ended March 31, 2023 and 2022, the Company did not incur, and therefore did not defer, any material incremental costs to obtain contracts or costs to fulfill contracts.

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Stockholders' Equity

3 Months Ended

Mar. 31, 2023

Stockholders' Equity

Stockholders' Equity

4.    Stockholders’ Equity

Common Stock

During the year ended December 31, 2022, the Company issued 1,195,208 shares of common stock as a result of stock option exercises, receiving gross proceeds of $2.9 million.

During the three months ended March 31, 2023, the Company issued 506,832 shares of common stock as a result of stock option exercises, receiving gross proceeds of $1.5 million.

Preferred Stock

The Company’s certificate of incorporation authorizes the issuance of up to 5,000,000 shares of preferred stock, par value $0.01 per share. As of March 31, 2023 and December 31, 2022, no shares of preferred stock were issued or outstanding.

Stock Incentive Plans

The Company adopted the MaxCyte, Inc. Long-Term Incentive Plan (the “2016 Plan”) in January 2016 to provide for the awarding of (i) stock options, (ii) restricted stock, (iii) incentive shares, and (iv) performance awards to employees, officers, and directors of the Company and to other individuals as determined by the board of directors.

In December 2021, the Company adopted the MaxCyte, Inc. 2021 Inducement Plan (the “Inducement Plan”) to provide for the awarding of (i) non-qualified stock options; (ii) stock appreciation rights; (iii) restricted stock awards; (iv) restricted stock unit awards; (v) performance awards; and (vi) other awards only to persons eligible to receive grants of awards who satisfy the standards for inducement grants under Nasdaq Marketplace Rule 5635(c)(4) or 5635(c)(3), if applicable, and the related guidance under Nasdaq IM 5635-1. The board of directors reserved 2,500,000 shares for issuance under the Inducement Plan.

In May 2022, the Company’s board of directors adopted, and in June 2022 the Company’s stockholders approved, the MaxCyte, Inc. 2022 Equity Incentive Plan (the “2022 Plan”) to provide for the awarding of (i) incentive stock options, (ii) non-qualified stock options, (iii) stock appreciation rights, (iv) restricted stock awards, (v) restricted stock unit awards, (vi) performance awards, and (vii) other awards. Following the approval of the 2022 Plan, no additional awards can be granted under the 2016 Plan or the Inducement Plan, but all outstanding awards will continue to remain subject to the terms of the applicable plan.

Upon the effectiveness of the 2022 Plan, a total of 3,692,397 shares were initially reserved for issuance pursuant to future awards under the 2022 Plan, consisting of 1,928,000 new shares and 1,764,397 shares previously available under the 2016 Plan. If and to the extent that outstanding options under the 2016 Plan or the Inducement Plan are forfeited, the shares underlying such forfeited options will become available for issuance under the 2022 Plan.

The Company has not issued performance awards under any plan.

At March 31, 2023 and December 31, 2022, there were 733,225 and 3,455,656 shares, respectively, available to be issued under the 2022 Plan.

The value of an equity award is recognized as expense on a straight-line basis over the requisite service period. At March 31, 2023, total unrecognized compensation expense was $33,142,200, which will be recognized over an estimated weighted average period of 2.73 years.

Stock Options

The weighted-average fair value of the stock options granted during the three months ended March 31, 2023 and 2022 was estimated to be $2.04 and $6.93, respectively per option share.

Restricted Stock Units (“RSUs”)

The weighted-average fair value of the RSUs granted during the three months ended March 31, 2023 was estimated to be $4.35 per RSU. The Company did not issue any RSUs before July 2022.

The Company recorded stock-based compensation expense in the following expense categories of its condensed consolidated statements of operations:

	Three months ended March 31,
	2023		2022
General and administrative	$	1,466,700	$	1,292,100
Sales and marketing		1,065,500		662,800
Research and development		744,400		507,500
Total	$	3,276,600	$	2,462,400

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Consolidated Balance Sheet Components

3 Months Ended

Mar. 31, 2023

Consolidated Balance Sheet Components

Consolidated Balance Sheet Components

5. Consolidated Balance Sheet Components

Inventory

Inventory is carried at the lower of cost or net realizable value. The following tables show the components of inventory:

	March 31,		December 31,
	2023		2022
Raw materials inventory	$	6,044,400	$	5,650,500
Finished goods inventory		3,549,500		2,930,300
Work in progress		671,000		—
Total inventory	$	10,264,900	$	8,580,800

The Company determined that no allowance for inventory obsolescence was necessary at March 31, 2023 or December 31, 2022.

Property and Equipment

Property and equipment are stated at cost. Depreciation is computed using the straight-line method. Leasehold improvements are amortized over the shorter of the estimated lease term or useful life.

Property and equipment include capitalized costs to develop internal-use software.  Applicable costs are capitalized during the development stage of the project and include direct internal costs, third-party costs and allocated interest expenses as appropriate.

Property and equipment consisted of the following:

	March 31,		December 31,
	2023		2022
Leasehold improvements	$	14,334,900	$	14,195,500
Furniture and equipment		11,516,400		9,516,500
Internal-use software		3,800,400		3,220,500
Instruments		2,430,300		2,440,300
Construction in process and internal-use software		82,300		627,400
Accumulated depreciation and amortization		(7,216,400)		(6,275,500)
Property and equipment, net	$	24,947,900	$	23,724,700

During the three months ended March 31, 2023 and 2022, the Company transferred $27,000 and $49,400, respectively, of instruments previously classified as inventory to property and equipment leased to customers.

For the three months ended March 31, 2023 and 2022, the Company incurred depreciation and amortization expense of $961,700 and $487,400, respectively.

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Fair Value

3 Months Ended

Mar. 31, 2023

Fair Value

Fair Value

6.    Fair Value

The Company’s condensed consolidated balance sheets include various financial instruments (primarily cash and cash equivalents, accounts receivable and accounts payable) that are carried at cost, which approximates fair value due to the short-term nature of the instruments.

Financial Assets and Liabilities Measured at Fair Value on a Recurring Basis

The Company had no financial assets or liabilities measured at fair value on a recurring basis as of March 31, 2023 or December 31, 2022.

Financial Assets and Liabilities Measured at Fair Value on a Non-Recurring Basis

Money market funds, US Treasury securities and government agency bonds, commercial paper and corporate debt instruments classified as held-to-maturity are measured at fair value on a non-recurring basis when they are deemed to be impaired on an other-than-temporary basis. The Company periodically reviews investments to assess for credit impairment. Based on its assessment, all unrecognized holding losses were due to factors other than credit loss, such as changes in interest rates. Therefore, no impairment was recognized during the three months ended March 31, 2023 or 2022.

The following table summarizes the Company’s financial instruments that were measured at fair value on a non-recurring basis at March 31, 2023:

				Gross		Gross
		Amortized		unrecognized		unrecognized		Aggregate
Description	Classification	cost		holding gains		holding losses		fair value
Money market funds and cash equivalents	Cash equivalents	$	28,327,600	$	—	$	—	$	28,327,600
Commercial paper	Cash equivalents		4,978,400		1,200				4,979,600
Commercial paper	Short-term investments		143,177,100		135,000		(62,000)		143,250,100
Corporate debt	Short-term investments		5,812,300		—		(14,900)		5,797,400
US Treasury securities and government agency bonds	Short-term investments		37,829,900		2,600		(122,100)		37,710,400
Total cash equivalents and short-term investments		$	220,125,300	$	138,800	$	(199,000)	$	220,065,100

The following table summarizes the Company’s financial instruments that were measured at fair value on a non-recurring basis at December 31, 2022:

				Gross		Gross
		Amortized		unrecognized		unrecognized		Aggregate
Description	Classification	cost		holding gains		holding losses		fair value
Money market funds and cash equivalents	Cash equivalents	$	5,741,800	$	—	$	—	$	5,741,800
Commercial paper	Short-term investments		172,740,700		156,400		(235,700)		172,661,400
Corporate debt	Short-term investments		5,792,000		—		(42,700)		5,749,300
US Treasury securities and government agency bonds	Short‑term investments		37,742,200		4,500		(196,100)		37,550,600
Total cash equivalents and short-term investments		$	222,016,700	$	160,900	$	(474,500)	$	221,703,100

Non-Financial Assets and Liabilities Measured at Fair Value on a Recurring Basis

The Company has no non-financial assets and liabilities that are measured at fair value on a recurring basis.

Non-Financial Assets and Liabilities Measured at Fair Value on a Non-Recurring Basis

The Company measures its long-lived assets, including property and equipment, at fair value on a non-recurring basis. These assets are recognized at fair value when they are deemed to be impaired. No fair value impairment was recognized during the three months ended March 31, 2023 and 2022.

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Commitments and Contingencies

3 Months Ended

Mar. 31, 2023

Commitments and Contingencies.

Commitments and Contingencies

7.  Commitments and Contingencies

Operating Leases

The Company was a party to various leases for office and laboratory and other space that were terminated in 2022. A member of the Company’s board of directors was previously the Chief Executive Officer and a member of the board of directors of the lessor of certain of these leases for which the rent payments totaled $163,700 in the three months ended March 31, 2022.

In May 2021, the Company entered into a lease for its new headquarters (the “New Headquarters Lease”), consisting of an operating lease agreement, as amended, for new office, laboratory, manufacturing and other space. The New Headquarters Lease consists of three phases, with Phase 1 having commenced in December 2021 and Phase 2 having commenced in the first quarter of 2022. Phase 3 is expected to begin in the second half of 2023. The lease term for all phases expires on August 31, 2035. The Company designed and constructed the leasehold improvements with the approval of the landlord. The New Headquarters Lease agreement includes a landlord-provided tenant improvement allowance (“TIA”) of $6.3 million to offset the cost of construction of leasehold improvements. As of March 31, 2023, the Company had received TIA reimbursements of $5.2 million. Under the New Headquarters Lease, the Company has three five-year options to extend the term of the lease. However, the Company is not reasonably certain to exercise any of these options. The total incremental non-cancellable lease payments under the New Headquarters Lease are approximately $29.6 million over the lease term.

The Company had no finance leases as of March 31, 2023 and December 31, 2022.

The components of lease cost and supplemental balance sheet information for the Company’s lease portfolio were as follows:

	Three months ended March 31,
	2023		2022
Operating lease cost	$	489,400	$	416,300
Short-term lease cost		10,000		12,100
Variable lease cost		165,200		75,400
Total lease cost	$	664,600	$	503,800

	As of March 31,		As of December 31,
	2023		2022
Operating leases
Assets:
Operating lease right of use assets	$	9,757,600	$	9,853,500
Liabilities
Current portion of operating lease liabilities	$	475,200	$	156,800
Operating lease liabilities, net of current portion		15,777,200		15,938,100
Total operating lease liabilities	$	16,252,400	$	16,094,900
Other information
Weighted-average remaining lease term (in years)		12.4		12.7
Weighted-average incremental borrowing rate		6.5%		6.5%

As of March 31, 2023, maturities of lease liabilities that had commenced prior to March 31, 2023 were as follows:

	Operating Leases
Remainder of 2023	$	1,121,800
2024		1,734,500
2025		1,777,700
2026		1,822,100
2027		1,867,700
2028 and thereafter		15,963,200
Total undiscounted lease payments		24,287,000
Discount factor		(8,034,600)
Present value of lease liabilities	$	16,252,400

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Summary of Significant Accounting Policies (Policies)

3 Months Ended

Mar. 31, 2023

Summary of Significant Accounting Policies

Basis of Presentation

Basis of Presentation

The accompanying unaudited condensed consolidated interim financial statements have been prepared in accordance with accounting principles generally accepted in the United States of America (“U.S. GAAP”) for interim financial information and pursuant to the instructions to Form 10-Q and Article 10 of Regulation S-X of the United States Securities and Exchange Commission (the “SEC”). In the Company’s opinion, the accompanying unaudited condensed consolidated financial statements include all adjustments, consisting of normal recurring adjustments, which are necessary to present fairly the financial position, results of operations, and cash flows as of and for the periods presented. The condensed consolidated balance sheet at December 31, 2022 has been derived from audited consolidated financial statements as of that date. The unaudited condensed consolidated results of operations are not necessarily indicative of the results that may occur for the full fiscal year or any other future year or period. Certain information and footnotes disclosure normally included in financial statements prepared in accordance with U.S. GAAP have been omitted pursuant to instructions, rules, and regulations prescribed by the SEC. The Company believes that the disclosures provided herein are adequate to make the information presented not misleading when these unaudited interim condensed consolidated financial statements are read in conjunction with the audited consolidated financial statements and notes included in the Company’s Annual Report on Form 10-K filed with the SEC on March 15, 2023.

Principles of Consolidation

Basis of Consolidation

The consolidated financial statements include the accounts of the Company and its wholly-owned subsidiary. All significant intercompany balances have been eliminated in consolidation.

Accounts Receivable

Accounts Receivable

Accounts receivable are reduced by an allowance for doubtful accounts, if needed. The Company determined that no allowance was necessary at March 31, 2023 or December 31, 2022.

Concentrations of Risk

Concentration of Risk

The Company maintains its cash and cash equivalents with two financial institutions that management believes to be of high credit quality. At times the Company’s cash balances may exceed federally insured limits and cash may also be deposited in foreign bank accounts that are not covered by federal deposit insurance. The Company does not believe that this results in any significant credit risk beyond the normal credit risk associated with commercial banking relationships.

Significant customers are those that accounted for 10% or more of the Company’s total revenue for the period or accounts receivable as of the end of a reporting period. During the three months ended March 31, 2023, two customers represented 23% and 11% of revenue, respectively. During the three months ended March 31, 2022, one customer represented 33% of revenue. As of March 31, 2023, two customers accounted for 23% and 12% of accounts receivable, respectively. As of December 31, 2022, one customer accounted for 14% of accounts receivable.

Certain components included in the Company’s products are obtained from a single source or a limited group of suppliers. During the three months ended March 31, 2023 and 2022, the Company purchased 60% and 39%, respectively, of its inventory from one supplier. As of March 31, 2023, amounts payable to one supplier totaled 21% of total accounts payable. At December 31, 2022, amounts payable to two suppliers totaled 34% of total accounts payable.

Foreign Currency

Foreign Currency

The Company’s functional currency is the US dollar; transactions denominated in foreign currencies are subject to currency risk. The Company recognized $6,100 in foreign currency transaction gains and $23,200 in foreign currency transaction losses for the three months ended March 31, 2023 and 2022, respectively.

Leases

Leases

For transactions in which the Company is the lessee, at the inception of a contract, the Company determines if the arrangement is, or contains, a lease. See Note 7 for additional details about leases under which the Company is the lessee.

All transactions in which the Company is the lessor are short-term (one year or less) and have been classified as operating leases. All leases require upfront payments covering the full period of the lease and thus, there are no future payments expected to be received from existing leases. See Note 3 for details on revenue recognition related to lease agreements.

Loss Per Share

Loss Per Share

Basic loss per share is computed by dividing net loss available to common stockholders by the weighted average number of shares of common stock outstanding during the period.

For periods of net income, and when the effects are not anti-dilutive, diluted earnings per share is computed by dividing net income available to common stockholders by the weighted-average number of shares outstanding plus the impact of all potential dilutive common shares, consisting primarily of common stock options and restricted stock units, and in the prior year periods stock purchase warrants, using the treasury stock method.

For periods of net loss, diluted loss per share is calculated similarly to basic loss per share because the impact of all dilutive potential common shares is anti-dilutive. The number of anti-dilutive shares excluded from the computation of diluted loss per share, consisting of shares underlying stock options and restricted stock units, was 17.1 million for the three months ended March 31, 2023 and 15.1 million for the three months ended March 31, 2022.

Recent Accounting Pronouncements

Recent Accounting Pronouncements

New Accounting Pronouncements Adopted

In June 2016, the Financial Accounting Standards Board (“FASB”) issued guidance with respect to measuring credit losses on financial instruments, including trade receivables. The guidance eliminates the probable initial recognition threshold that was previously required prior to recognizing a credit loss on financial instruments. The credit loss estimate can now reflect an entity’s current estimate of all future expected credit losses. Under the previous guidance, an entity only considered past events and current conditions. The current guidance is effective for fiscal years beginning after December 15, 2022, including interim periods within those fiscal years. The adoption of certain amendments of this guidance must be applied on a modified retrospective basis and the adoption of the remaining amendments must be applied on a prospective basis. The Company adopted this new accounting pronouncement effective on January 1, 2023, and the adoption did not have a material impact on its consolidated financial statements.

The Company has evaluated all other issued and unadopted Accounting Standards Updates and believes the adoption of these standards will not have a material impact on its results of operations, financial position, or cash flows.

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Revenue (Tables)

3 Months Ended

Mar. 31, 2023

Revenue

Schedule of disaggregation of revenue

	Three months ended March 31, 2023
	Revenue from		Revenue
	Contracts		from
	with		Lease		Total
	Customers		Elements		Revenue
Product sales	$	4,789,700	$	—	$	4,789,700
Lease elements		—		3,612,800		3,612,800
Other		173,800		—		173,800
Total	$	4,963,500	$	3,612,800	$	8,576,300

	Three months ended March 31, 2022
	Revenue from		Revenue
	Contracts		from
	with		Lease		Total
	Customers		Elements		Revenue
Product sales	$	6,567,600	$	—	$	6,567,600
Lease elements		—		4,730,000		4,730,000
Other		289,700		—		289,700
Total	$	6,857,300	$	4,730,000	$	11,587,300

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Stockholders' Equity (Tables)

3 Months Ended

Mar. 31, 2023

Stockholders' Equity

Schedule of stock-based compensation expense

	Three months ended March 31,
	2023		2022
General and administrative	$	1,466,700	$	1,292,100
Sales and marketing		1,065,500		662,800
Research and development		744,400		507,500
Total	$	3,276,600	$	2,462,400

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Consolidated Balance Sheet Components (Tables)

3 Months Ended

Mar. 31, 2023

Consolidated Balance Sheet Components

Schedule of inventory

	March 31,		December 31,
	2023		2022
Raw materials inventory	$	6,044,400	$	5,650,500
Finished goods inventory		3,549,500		2,930,300
Work in progress		671,000		—
Total inventory	$	10,264,900	$	8,580,800

Schedule of property and equipment

	March 31,		December 31,
	2023		2022
Leasehold improvements	$	14,334,900	$	14,195,500
Furniture and equipment		11,516,400		9,516,500
Internal-use software		3,800,400		3,220,500
Instruments		2,430,300		2,440,300
Construction in process and internal-use software		82,300		627,400
Accumulated depreciation and amortization		(7,216,400)		(6,275,500)
Property and equipment, net	$	24,947,900	$	23,724,700

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Fair Value (Tables)

3 Months Ended

Mar. 31, 2023

Fair Value

Summary of the Company's cash equivalents and investments

The following table summarizes the Company’s financial instruments that were measured at fair value on a non-recurring basis at March 31, 2023:

				Gross		Gross
		Amortized		unrecognized		unrecognized		Aggregate
Description	Classification	cost		holding gains		holding losses		fair value
Money market funds and cash equivalents	Cash equivalents	$	28,327,600	$	—	$	—	$	28,327,600
Commercial paper	Cash equivalents		4,978,400		1,200				4,979,600
Commercial paper	Short-term investments		143,177,100		135,000		(62,000)		143,250,100
Corporate debt	Short-term investments		5,812,300		—		(14,900)		5,797,400
US Treasury securities and government agency bonds	Short-term investments		37,829,900		2,600		(122,100)		37,710,400
Total cash equivalents and short-term investments		$	220,125,300	$	138,800	$	(199,000)	$	220,065,100

The following table summarizes the Company’s financial instruments that were measured at fair value on a non-recurring basis at December 31, 2022:

				Gross		Gross
		Amortized		unrecognized		unrecognized		Aggregate
Description	Classification	cost		holding gains		holding losses		fair value
Money market funds and cash equivalents	Cash equivalents	$	5,741,800	$	—	$	—	$	5,741,800
Commercial paper	Short-term investments		172,740,700		156,400		(235,700)		172,661,400
Corporate debt	Short-term investments		5,792,000		—		(42,700)		5,749,300
US Treasury securities and government agency bonds	Short‑term investments		37,742,200		4,500		(196,100)		37,550,600
Total cash equivalents and short-term investments		$	222,016,700	$	160,900	$	(474,500)	$	221,703,100

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Commitments and Contingencies (Tables)

3 Months Ended

Mar. 31, 2023

Commitments and Contingencies.

Schedule of lease costs

	Three months ended March 31,
	2023		2022
Operating lease cost	$	489,400	$	416,300
Short-term lease cost		10,000		12,100
Variable lease cost		165,200		75,400
Total lease cost	$	664,600	$	503,800

Schedule of operating lease assets, liabilities and other information

	As of March 31,		As of December 31,
	2023		2022
Operating leases
Assets:
Operating lease right of use assets	$	9,757,600	$	9,853,500
Liabilities
Current portion of operating lease liabilities	$	475,200	$	156,800
Operating lease liabilities, net of current portion		15,777,200		15,938,100
Total operating lease liabilities	$	16,252,400	$	16,094,900
Other information
Weighted-average remaining lease term (in years)		12.4		12.7
Weighted-average incremental borrowing rate		6.5%		6.5%

Schedule of maturities of operating lease liabilities

	Operating Leases
Remainder of 2023	$	1,121,800
2024		1,734,500
2025		1,777,700
2026		1,822,100
2027		1,867,700
2028 and thereafter		15,963,200
Total undiscounted lease payments		24,287,000
Discount factor		(8,034,600)
Present value of lease liabilities	$	16,252,400

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Organization and Description of Business (Details) - USD ($) $ / shares in Units, $ in Millions		3 Months Ended	12 Months Ended
	Aug. 03, 2021	Mar. 31, 2023	Dec. 31, 2022
Product Information [Line Items]
Shares issued	15,525,000	506,832	1,195,208
Share price	$ 13.00
Gross proceeds	$ 201.8
Net proceeds	184.3
Payment of underwriting commissions and offering costs	$ 17.6
Underwriter's option
Product Information [Line Items]
Shares issued	2,025,000

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Summary of Significant Accounting Policies - Concentration of Risk (Details)	3 Months Ended		12 Months Ended
	Mar. 31, 2023 USD ($) customer item	Mar. 31, 2022 customer item	Dec. 31, 2022 USD ($) item
Allowance for doubtful accounts
Allowance for doubtful accounts | $	$ 0		$ 0
Major suppliers
Concentration Risk [Line Items]
Number of major suppliers | item	1		2
Revenue.
Concentration Risk [Line Items]
Number of major customers	2
Revenue. | Customer concentration risk | Two Customers
Concentration Risk [Line Items]
Concentration risk percentage	11.00%
Revenue. | Customer concentration risk | Customer one
Concentration Risk [Line Items]
Number of major customers		1
Concentration risk percentage		33.00%
Revenue. | Customer concentration risk | Customer two
Concentration Risk [Line Items]
Concentration risk percentage	23.00%
Accounts receivable
Concentration Risk [Line Items]
Number of major customers		1
Accounts receivable | Customer concentration risk | Two Customers
Concentration Risk [Line Items]
Number of major customers	2
Accounts receivable | Customer concentration risk | Customer one
Concentration Risk [Line Items]
Concentration risk percentage	23.00%	14.00%
Accounts receivable | Customer concentration risk | Customer two
Concentration Risk [Line Items]
Concentration risk percentage	12.00%
Inventory | Supplier concentration risk | Major suppliers
Concentration Risk [Line Items]
Concentration risk percentage	60.00%	39.00%
Number of major suppliers | item	1	1
Accounts payable | Supplier concentration risk | Major suppliers
Concentration Risk [Line Items]
Concentration risk percentage	21.00%		34.00%

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Summary of Significant Accounting Policies - Foreign Currency (Details) - USD ($)	3 Months Ended
	Mar. 31, 2023	Mar. 31, 2022
Summary of Significant Accounting Policies
Foreign currency transaction gains (losses)	$ (6,100)	$ 23,200

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Summary of Significant Accounting Policies - Loss Per Share (Details) - shares shares in Millions	3 Months Ended
	Mar. 31, 2023	Mar. 31, 2022
Loss Per Share
Anti-dilutive shares excluded from the computation of diluted loss per share	17.1	15.1

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Revenue - Disaggregation of revenue (Details) - USD ($)	3 Months Ended
	Mar. 31, 2023	Mar. 31, 2022
Disaggregation of Revenue [Line Items]
Revenue from Contracts with Customers	$ 4,963,500	$ 6,857,300
Revenue from Lease Elements	3,612,800	4,730,000
Total Revenue	8,576,300	11,587,300
Product sales
Disaggregation of Revenue [Line Items]
Revenue from Contracts with Customers	4,789,700	6,567,600
Total Revenue	4,789,700	6,567,600
Other
Disaggregation of Revenue [Line Items]
Revenue from Contracts with Customers	173,800	289,700
Total Revenue	$ 173,800	$ 289,700

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Revenue - Changes in deferred revenue (Details) - USD ($) $ in Millions	3 Months Ended
	Mar. 31, 2023	Mar. 31, 2022	Dec. 31, 2022
Change in Contract with Customer, Liability [Abstract]
Deferred revenue	$ 6.1		$ 7.0
Revenue recognized	$ 2.6	$ 2.6

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Revenue - Performance Obligations (Details)	Mar. 31, 2023 USD ($)
Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction [Line Items]
Remaining performance obligation	$ 405,200
Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction, Start Date [Axis]: 2023-04-01
Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction [Line Items]
Remaining performance obligation	$ 94,700
Remaining performance obligation expects to recognize as revenue	1 year
Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction, Start Date [Axis]: 2024-04-01
Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction [Line Items]
Remaining performance obligation	$ 94,700
Remaining performance obligation expects to recognize as revenue	2 years
Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction, Start Date [Axis]: 2025-04-01
Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction [Line Items]
Remaining performance obligation	$ 47,300
Remaining performance obligation expects to recognize as revenue	3 years
Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction, Start Date [Axis]: 2026-04-01
Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction [Line Items]
Remaining performance obligation	$ 168,500
Remaining performance obligation expects to recognize as revenue	0 years

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Stockholders' Equity - Common Stock (Details) - USD ($)		3 Months Ended		12 Months Ended
	Aug. 03, 2021	Mar. 31, 2023	Mar. 31, 2022	Dec. 31, 2022
Stockholders' Equity
Shares issued	15,525,000	506,832		1,195,208
Share price	$ 13.00
Gross proceeds		$ 1,500,000		$ 2,900,000
Proceeds from exercise of stock options		$ 1,456,600	$ 892,600
Cost incurred	$ 17,600,000
Proceeds from Issuance Initial Public Offering	$ 184,300,000
Preferred stock, authorized (in shares)		5,000,000		5,000,000
Preferred stock, par value (in dollars per share)		$ 0.01		$ 0.01
Preferred stock, issued (in shares)		0		0
Preferred stock, outstanding (in shares)		0		0

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Stockholders' Equity - Equity Incentive Plans (Details) - USD ($)	3 Months Ended
	Mar. 31, 2023	Mar. 31, 2022	Dec. 31, 2022	May 31, 2022	Dec. 31, 2021
Inducement Plan
Share-based Compensation Arrangement by Share-based Payment Award [Line Items].
Awards available to be issued					2,500,000
2022 Plan
Share-based Compensation Arrangement by Share-based Payment Award [Line Items].
Awards available to be issued				3,692,397
New shares				1,928,000
Shares available that were transferred from the 2016 Plan				1,764,397
Weighted-average fair value of the options granted	$ 2.04	$ 6.93
Unrecognized compensation expense	$ 33,142,200
Unrecognized compensation expense, recognition period	2 years 8 months 23 days
2022 Plan | RSUs
Share-based Compensation Arrangement by Share-based Payment Award [Line Items].
Awards available to be issued	733,225		3,455,656
Weighted Average Market Price, Granted (in dollars per share)	$ 4.35

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Stockholders' Equity - Stock-based compensation expense (Details) - USD ($)	3 Months Ended
	Mar. 31, 2023	Mar. 31, 2022
Share-based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]
Stock-based compensation expense	$ 3,276,600	$ 2,462,400
General and administrative
Share-based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]
Stock-based compensation expense	1,466,700	1,292,100
Research and development
Share-based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]
Stock-based compensation expense	744,400	507,500
Sales and marketing
Share-based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]
Stock-based compensation expense	$ 1,065,500	$ 662,800

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Consolidated Balance Sheet Components - Inventory (Details) - USD ($)	Mar. 31, 2023	Dec. 31, 2022
Consolidated Balance Sheet Components
Raw materials inventory	$ 6,044,400	$ 5,650,500
Work in progress	671,000
Finished goods inventory	3,549,500	2,930,300
Total inventory	10,264,900	8,580,800
Allowance for obsolescence	$ 0	$ 0

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Consolidated Balance Sheet Components - Property and equipment, Net (Details) - USD ($)	3 Months Ended
	Mar. 31, 2023	Mar. 31, 2022	Dec. 31, 2022
Property and equipment, Net
Accumulated depreciation and amortization	$ (7,216,400)		$ (6,275,500)
Property and equipment, net	24,947,900		23,724,700
Transfer of instruments	27,000	$ 49,400
Depreciation and amortization	961,700	$ 487,400
Leasehold improvements
Property and equipment, Net
Property and equipment, gross	14,334,900		14,195,500
Furniture and equipment
Property and equipment, Net
Property and equipment, gross	11,516,400		9,516,500
Internal-use software
Property and equipment, Net
Property and equipment, gross	3,800,400		3,220,500
Instruments
Property and equipment, Net
Property and equipment, gross	2,430,300		2,440,300
Construction in process and internal-use software
Property and equipment, Net
Property and equipment, gross	$ 82,300		$ 627,400

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Fair Value - Assets and Liabilities Measured at Fair Value on a Non-Recurring Basis (Details) - Non-recurring basis - USD ($)	3 Months Ended
	Mar. 31, 2023	Mar. 31, 2022
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Impairment of short-term investments	$ 0	$ 0
Impairment of long-lived assets	$ 0	$ 0

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Fair Value - Financial Instruments (Details) - USD ($)	Mar. 31, 2023	Dec. 31, 2022
Cash and Cash Equivalents [Line Items]
Amortized cost	$ 37,833,400	$ 11,064,700
Non-recurring basis
Cash and Cash Equivalents [Line Items]
Amortized cost	220,125,300	222,016,700
Gross unrecognized holding gains	138,800	160,900
Gross unrecognized holding losses	(199,000)	(474,500)
Aggregate fair value	220,065,100	221,703,100
Non-recurring basis | Commercial paper
Cash and Cash Equivalents [Line Items]
Amortized cost	143,177,100	172,740,700
Gross unrecognized holding gains	135,000	156,400
Gross unrecognized holding losses	(62,000)	(235,700)
Aggregate fair value	143,250,100	172,661,400
Non-recurring basis | Corporate debt
Cash and Cash Equivalents [Line Items]
Amortized cost	5,812,300	5,792,000
Gross unrecognized holding losses	(14,900)	(42,700)
Aggregate fair value	5,797,400	5,749,300
Non-recurring basis | US Treasury securities and government agency bonds
Cash and Cash Equivalents [Line Items]
Amortized cost	37,829,900	37,742,200
Gross unrecognized holding gains	2,600	4,500
Gross unrecognized holding losses	(122,100)	(196,100)
Aggregate fair value	37,710,400	37,550,600
Non-recurring basis | Money market funds and cash equivalents
Cash and Cash Equivalents [Line Items]
Amortized cost	28,327,600	5,741,800
Aggregate fair value	28,327,600	$ 5,741,800
Non-recurring basis | Commercial paper | Commercial paper
Cash and Cash Equivalents [Line Items]
Amortized cost	4,978,400
Gross unrecognized holding gains	1,200
Aggregate fair value	$ 4,979,600

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Commitments and Contingencies - Operating Leases (Details)	3 Months Ended
	Mar. 31, 2023 USD ($) item	Mar. 31, 2022 USD ($)	Dec. 31, 2022 USD ($)
Commitments and Contingencies
Incremental non-cancellable lease payments	$ 24,287,000
Accounts receivable - TIA	996,600		$ 1,912,400
Right-of-use asset - operating leases	9,757,600		$ 9,853,500
Lease liabilities	16,252,400
New Office and Manufacturing Space
Commitments and Contingencies
Incremental non-cancellable lease payments	29,600,000
Tenant improvement allowance	6,300,000
TIA reimbursements	$ 5,200,000
Number of options to extend lease | item	3
Renewal term	5 years
Office and Laboratory Space | Chairman of the Board along with a Director
Commitments and Contingencies
Lease rent payments		$ 163,700

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Commitments and Contingencies - Lease costs (Details) - USD ($)	3 Months Ended
	Mar. 31, 2023	Mar. 31, 2022	Dec. 31, 2022
Lease costs
Operating lease cost	$ 489,400	$ 416,300
Short-term lease cost	10,000	12,100
Variable lease cost	165,200	75,400
Total lease cost	664,600	$ 503,800
Assets:
Operating lease right-of-use assets	9,757,600		$ 9,853,500
Liabilities
Current portion of operating lease liabilities	475,200		156,800
Operating lease liabilities, net of current portion	15,777,200		15,938,100
Total operating lease liabilities	$ 16,252,400		$ 16,094,900
Other information
Weighted-average remaining lease term (in years)	12 years 4 months 24 days		12 years 8 months 12 days
Weighted-average discount rate%	6.50%		6.50%

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Commitments and Contingencies - Maturities of lease liabilities (Details)	Mar. 31, 2023 USD ($)
Maturities of operating lease liabilities
Remainder of 2023	$ 1,121,800
2024	1,734,500
2025	1,777,700
2026	1,822,100
2027	1,867,700
Total undiscounted lease payments	24,287,000
Discount factor	(8,034,600)
Present value of lease liabilities	16,252,400
2026 and thereafter	$ 15,963,200