CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2022	Sep. 30, 2021	Sep. 30, 2022	Sep. 30, 2021
Costs and expenses:
Research and development	$ 38,568	$ 25,818	$ 86,172	$ 88,448
Selling, general and administrative	12,198	14,010	37,079	42,280
Total costs and expenses	50,766	39,828	123,251	130,728
Loss from continuing operations	(50,766)	(39,828)	(123,251)	(130,728)
Interest expense	(4,932)	(4,911)	(14,799)	(14,718)
Interest and other income	906	461	2,069	1,212
Net loss from continuing operations	(54,792)	(44,278)	(135,981)	(144,234)
Net income from discontinued operations	37,336	21,575	54,665	57,848
Net loss	$ (17,456)	$ (22,703)	$ (81,316)	$ (86,386)
Basic net income (loss) per share continuing operations	$ (0.87)	$ (0.70)	$ (2.17)	$ (2.32)
Basic net income (loss) per share discontinued operations	0.59	0.34	0.87	0.93
Basic net income (loss) per share	(0.28)	(0.36)	(1.30)	(1.39)
Diluted net income (loss) per share continuing operations	(0.87)	(0.70)	(2.17)	(2.32)
Diluted net income (loss) per share discontinued operations	0.59	0.34	0.87	0.93
Diluted net income (loss) per share	$ (0.28)	$ (0.36)	$ (1.30)	$ (1.39)
Weighted-average shares used to compute basic net income (loss) per share (in shares)	62,730,015	62,510,727	62,728,276	62,267,557
Weighted-average shares used to compute diluted net income (loss) per share (in shares)	62,730,015	62,510,727	62,728,276	62,267,557