Certain Balance Sheet Accounts - Property and Equipment, Net (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2022	Sep. 30, 2021	Sep. 30, 2022	Sep. 30, 2021	Dec. 31, 2021
Property, Plant and Equipment [Line Items]
Total cost	$ 11,607		$ 11,607		$ 10,764
Less accumulated depreciation and amortization	(9,760)		(9,760)		(9,033)
Total property and equipment, net	1,847		1,847		1,731
Depreciation and amortization	300	$ 300	789	$ 1,062
Finance leases
Property, Plant and Equipment [Line Items]
Total cost	6,785		6,785		5,979
Laboratory equipment
Property, Plant and Equipment [Line Items]
Total cost	3,121		3,121		3,091
Computer equipment
Property, Plant and Equipment [Line Items]
Total cost	1,076		1,076		1,069
Office equipment and furniture
Property, Plant and Equipment [Line Items]
Total cost	$ 625		$ 625		$ 625