X0306 4 2020-09-30 0 0001285550 ClearPoint Neuro, Inc. CLPT 0001601831 Richards Timothy T. C/O CLEARPOINT NEURO, INC. 5 MUSICK IRVINE CA 92618 1 0 0 0 Common Stock 2020-09-30 4 A 0 1051 5.71 A 17216 D These shares were issued pursuant to the issuer's Third Amended and Restated 2013 Incentive Compensation Plan, in payment of fees owed to the reporting person under the issuer's Non-Employee Director Compensation Plan, as amended and restated. The shares were issued at a price of $5.71 per share, representing the volume-weighted average price of the issuer's common stock for the five-trading day period ended September 30, 2020. Richard F. Mattern, by Power of Attorney for Timothy T. Richards 2020-10-01