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Income Taxes - Schedule of Reconciliation Between Effective Tax Rates and Statutory Rates (Detail)
12 Months Ended
Dec. 31, 2017
Dec. 31, 2016
Effective Income Tax Rate Reconciliation, Percent [Abstract]    
Computed at statutory rate 34.00% 34.00%
State income taxes 4.34% 4.76%
Tax credits 1.76% 3.38%
Other (6.04%) (1.74%)
Federal rate change (79.56%)  
Valuation allowance 45.50% (40.40%)
Effective Income Tax Rate Reconciliation,Total 0.00% 0.00%