Consolidated Statements of Stockholders' Equity - USD ($) $ in Thousands	Common Stock [Member]	Additional Paid-In Capital [Member]	Accumulated Other Comprehensive Income/(Loss) [Member]	Accumulated Deficit [Member]	Total
Beginning Balance at Dec. 31, 2020	$ 610	$ 825,794	$ (42)	$ (322,843)	$ 503,519
Beginning Balance (in shares) at Dec. 31, 2020	60,996,367
Issuance of common stock pursuant to exercise of stock options	$ 9	8,783	0	0	8,792
Issuance of common stock pursuant to exercise of stock options (in shares)	991,432
Unrealized comprehensive gain (loss) on investments	$ 0	0	(33)	0	(33)
Stock-based compensation	0	7,900	0	0	7,900
Net loss	0	0	0	(40,179)	(40,179)
Ending Balance at Mar. 31, 2021	$ 619	842,477	(75)	(363,022)	479,999
Ending Balance (in shares) at Mar. 31, 2021	61,987,799
Beginning Balance at Dec. 31, 2020	$ 610	825,794	(42)	(322,843)	503,519
Beginning Balance (in shares) at Dec. 31, 2020	60,996,367
Unrealized comprehensive gain (loss) on investments					(55)
Net loss					(124,822)
Ending Balance at Sep. 30, 2021	$ 644	932,776	(97)	(447,665)	485,658
Ending Balance (in shares) at Sep. 30, 2021	64,442,601
Beginning Balance at Mar. 31, 2021	$ 619	842,477	(75)	(363,022)	479,999
Beginning Balance (in shares) at Mar. 31, 2021	61,987,799
Issuance of common stock pursuant to exercise of stock options	$ 2	1,113	0	0	1,115
Issuance of common stock pursuant to exercise of stock options (in shares)	133,838
Issuance of common stock pursuant to conversion of notes	$ 13	35,530	0	0	35,543
Issuance of common stock pursuant to conversion of notes (in shares)	1,326,432
Unrealized comprehensive gain (loss) on investments	$ 0	0	(6)	0	(6)
Stock-based compensation	0	7,311	0	0	7,311
Net loss	0	0	0	(34,525)	(34,525)
Ending Balance at Jun. 30, 2021	$ 634	886,431	(81)	(397,547)	489,437
Ending Balance (in shares) at Jun. 30, 2021	63,448,069
Issuance of common stock pursuant to exercise of stock options	$ 0	284	0	0	284
Issuance of common stock pursuant to exercise of stock options (in shares)	21,402
Issuance of common stock pursuant to conversion of notes	$ 2	5,148	0	0	5,150
Issuance of common stock pursuant to conversion of notes (in shares)	160,614
Issuance of common stock pursuant to the at-the-market offering program, net of issuance costs	$ 8	26,346	0	0	26,354
Issuance of common stock pursuant to the at-the-market offering program, net of issuance costs (in shares)	812,516
Warrant Issuance	$ 0	7,578	0	0	7,578
Unrealized comprehensive gain (loss) on investments	0	0	(16)	0	(16)
Stock-based compensation	0	6,989	0	0	6,989
Net loss	0	0	0	(50,118)	(50,118)
Ending Balance at Sep. 30, 2021	$ 644	932,776	(97)	(447,665)	485,658
Ending Balance (in shares) at Sep. 30, 2021	64,442,601
Beginning Balance at Dec. 31, 2021	$ 645	946,152	(161)	(491,912)	454,724
Beginning Balance (in shares) at Dec. 31, 2021	64,505,889
Issuance of common stock pursuant to exercise of stock options and restricted stock units	$ 0	76	0	0	76
Issuance of common stock pursuant to exercise of stock options and restricted stock units (in shares)	16,168
Unrealized comprehensive gain (loss) on investments	$ 0	0	(468)	0	(468)
Stock-based compensation	0	6,270	0	0	6,270
Net loss	0	0	0	(42,982)	(42,982)
Ending Balance at Mar. 31, 2022	$ 645	952,498	(629)	(534,894)	417,620
Ending Balance (in shares) at Mar. 31, 2022	64,522,057
Beginning Balance at Dec. 31, 2021	$ 645	946,152	(161)	(491,912)	454,724
Beginning Balance (in shares) at Dec. 31, 2021	64,505,889
Unrealized comprehensive gain (loss) on investments					(435)
Net loss					(155,140)
Ending Balance at Sep. 30, 2022	$ 678	1,014,283	(596)	(647,052)	367,313
Ending Balance (in shares) at Sep. 30, 2022	67,838,803
Beginning Balance at Mar. 31, 2022	$ 645	952,498	(629)	(534,894)	417,620
Beginning Balance (in shares) at Mar. 31, 2022	64,522,057
Issuance of common stock pursuant to exercise of stock options	$ 0	3	0	0	3
Issuance of common stock pursuant to exercise of stock options (in shares)	2,387
Issuance of common stock pursuant to the at-the-market offering program, net of issuance costs	$ 13	17,229	0	0	17,242
Issuance of common stock pursuant to the at-the-market offering program, net of issuance costs (in shares)	1,313,450
Unrealized comprehensive gain (loss) on investments	$ 0	0	(136)	0	(136)
Stock-based compensation	0	7,369	0	0	7,369
Net loss	0	0	0	(54,402)	(54,402)
Ending Balance at Jun. 30, 2022	$ 658	977,099	(765)	(589,296)	387,696
Ending Balance (in shares) at Jun. 30, 2022	65,837,894
Issuance of common stock pursuant to exercise of stock options	$ 0	229	0	0	229
Issuance of common stock pursuant to exercise of stock options (in shares)	22,437
Issuance of common stock pursuant to the at-the-market offering program, net of issuance costs	$ 20	29,278	0	0	29,298
Issuance of common stock pursuant to the at-the-market offering program, net of issuance costs (in shares)	1,978,472
Unrealized comprehensive gain (loss) on investments	$ 0	0	169	0	169
Stock-based compensation	0	7,677	0	0	7,677
Net loss	0	0	0	(57,756)	(57,756)
Ending Balance at Sep. 30, 2022	$ 678	$ 1,014,283	$ (596)	$ (647,052)	$ 367,313
Ending Balance (in shares) at Sep. 30, 2022	67,838,803