Consolidated Statements of Operations - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2022	Sep. 30, 2021	Sep. 30, 2022	Sep. 30, 2021
Consolidated Statements of Operations [Abstract]
Revenue	$ 0	$ 0	$ 0	$ 0
Operating expenses:
Research and development	43,383	39,621	115,533	92,459
General and administrative	15,105	10,025	39,728	30,456
Total operating expenses	58,488	49,646	155,261	122,915
Loss from operations	(58,488)	(49,646)	(155,261)	(122,915)
Research and development incentives	0	0	0	500
Interest expense	(465)	(534)	(1,395)	(2,514)
Interest and other income, net	1,353	806	2,644	2,218
Amortization of premium on investments - net	(156)	(744)	(1,128)	(2,111)
Net loss	$ (57,756)	$ (50,118)	$ (155,140)	$ (124,822)
Net loss per share - basic (in dollars per share)	$ (0.87)	$ (0.79)	$ (2.37)	$ (1.99)
Net loss per share - diluted (in dollars per share)	$ (0.87)	$ (0.79)	$ (2.37)	$ (1.99)
Weighted-average common shares outstanding - basic (in shares)	66,215,535	63,825,429	65,406,844	62,828,601
Weighted-average common shares outstanding - diluted (in shares)	66,215,535	63,825,429	65,406,844	62,828,601