Risks and Liquidity (Details) - USD ($)	1 Months Ended	3 Months Ended
	Apr. 30, 2022	Mar. 31, 2022	Feb. 28, 2022	Dec. 31, 2021
Risks and Liquidity [Abstract]
Accumulated deficit		$ (534,894,000)		$ (491,912,000)
Cash, cash equivalents and investments		$ 346,600,000
Shareholders' Equity Disclosure [Abstract]
Common stock, par value (in dollars per share)		$ 0.01		$ 0.01
At-the-Market Offering [Member] | Subsequent Event [Member]
Shareholders' Equity Disclosure [Abstract]
Common stock shares issued and sold (in shares)	1,300,000
Issuance of common stock, net of issuance costs	$ 17,300,000
At-the-Market Offering [Member] | Cowen and Company, LLC [Member]
Shareholders' Equity Disclosure [Abstract]
Common stock, par value (in dollars per share)			$ 0.01
Aggregate offering price			$ 200,000,000
Common stock shares issued and sold (in shares)		0