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Net Loss Per Share (Tables)
9 Months Ended
Sep. 30, 2019
Net Loss Per Share [Abstract]  
Basic and Diluted Net Loss Per Share
Basic and diluted net loss per share attributable to common stockholders was calculated as follows:

  
Three Months Ended September 30,
  
Nine Months Ended September 30,
 
  
2019
  
2018
  
2019
  
2018
 
             
Numerator:
            
Net loss
 
$
(19,284
)
 
$
(16,089
)
 
$
(57,415
)
 
$
(47,199
)
Denominator:
                
Weighted-average common shares outstanding - basic and diluted
  
50,364,649
   
39,900,551
   
48,270,771
   
38,598,304
 
Net loss per share- basic and diluted
 
$
(0.38
)
 
$
(0.40
)
 
$
(1.19
)
 
$
(1.22
)
Antidilutive Securities Excluded from Computation of Diluted Net Loss Per Share
The Company excluded the following potential shares of common stock, presented based on amounts outstanding at each period end, from the computation of diluted net loss per share attributable to common stockholders for the periods indicated because including them would have had an anti-dilutive effect:

  
Three Months Ended September 30,
  
Nine Months Ended September 30,
 
  
2019
  
2018
  
2019
  
2018
 
Shares issuable upon conversion of the 2021 Convertible Notes
  
1,620,948
   
1,620,948
   
1,620,948
   
1,620,948
 
Warrants exercisable for common shares
  
14,102
   
14,102
   
14,102
   
14,102
 
Options to purchase common shares
  
9,608,537
   
8,475,802
   
9,608,537
   
8,475,802
 
   
11,243,587
   
10,110,852
   
11,243,587
   
10,110,852