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Net Loss Per Share (Tables)
6 Months Ended
Jun. 30, 2019
Net Loss Per Share [Abstract]  
Basic and Diluted Net Loss Per Share
Basic and diluted net loss per share attributable to common stockholders was calculated as follows:

  
Three Months Ended June 30,
  
Six Months Ended June 30,
 
  
2019
  
2018
  
2019
  
2018
 
             
Numerator:
            
Net loss
 
$
(18,680
)
 
$
(15,767
)
 
$
(38,131
)
 
$
(31,110
)
Denominator:
                
Weighted-average common shares outstanding - basic and diluted
  
49,267,247
   
39,483,006
   
47,206,480
   
37,954,972
 
Net loss per share- basic and diluted
 
$
(0.38
)
 
$
(0.40
)
 
$
(0.81
)
 
$
(0.82
)
Antidilutive Securities Excluded from Computation of Diluted Net Loss Per Share
The Company excluded the following potential shares of common stock, presented based on amounts outstanding at each period end, from the computation of diluted net loss per share attributable to common stockholders for the periods indicated because including them would have had an anti-dilutive effect:

  
Three Months Ended June 30,
  
Six Months Ended June 30,
 
  
2019
  
2018
  
2019
  
2018
 
Shares issuable upon conversion of the 2021 Convertible Notes
  
1,620,948
   
1,620,948
   
1,620,948
   
1,620,948
 
Warrants exercisable for common shares
  
14,102
   
14,102
   
14,102
   
14,102
 
Options to purchase common shares
  
9,432,575
   
8,870,004
   
9,432,575
   
8,870,004
 
   
11,067,625
   
10,505,054
   
11,067,625
   
10,505,054