Consolidated Statements of Cash Flows - USD ($) $ in Thousands	6 Months Ended
	Jun. 30, 2025	Jun. 30, 2024
Operating activities:
Net loss	$ (130,253)	$ (131,700)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization of property and equipment	4,491	3,548
Amortization of finance lease right of use asset	1,077	1,077
Stock-based compensation	21,188	21,584
Accretion of discount on investments, net	(4,287)	(4,996)
Change in fair value of warrant liabilities	0	(1,771)
Changes in operating assets and liabilities:
Prepaid expenses and other assets	200	(729)
Accounts payable and accrued expenses	2,863	2,122
Operating lease liabilities and right of use assets, net	22	50
Finance lease liability	25	56
Other liabilities	(80)	80
Net cash used in operating activities	(104,754)	(110,679)
Investing activities:
Purchases of investments	(192,620)	(102,521)
Proceeds from maturities of investments	166,760	197,144
Purchases of property and equipment	(414)	(3,965)
Net cash (used in) provided by investing activities	(26,274)	90,658
Financing activities:
Issuance of common stock, pursuant to exercise of stock options	0	2,714
Return of related party short swing profits	215
Net cash provided by financing activities	215	2,714
Net change in cash, cash equivalents and restricted cash	(130,813)	(17,307)
Cash, cash equivalents and restricted cash at beginning of period	164,997	57,276
Cash, cash equivalents and restricted cash at end of period	34,184	39,969
Supplemental disclosure of non-cash financing and investing activities:
Accrued purchases of property and equipment, ending balance	0	1,036
Investment maturity receivables and purchase payables, ending balance	0	8,072
Operating lease liabilities	0	1,134
Operating lease right of use assets	0	1,134
Net unrealized loss on investments	$ (173)	$ (537)