Consolidated Statements of Operations - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2024	Dec. 31, 2023	Dec. 31, 2022
Consolidated Statements of Operations [Abstract]
Revenue	$ 0	$ 0	$ 0
Operating expenses:
Research and development	171,244	186,342	165,570
General and administrative	101,961	73,317	58,773
Total operating expenses	273,205	259,659	224,343
Loss from operations	(273,205)	(259,659)	(224,343)
Research and development incentives	0	0	500
Interest expense	(1,886)	(1,875)	(1,862)
Interest and other income, net	8,267	5,288	3,889
Accretion of discount and amortization of premium on investments, net	8,078	10,651	(47)
Net loss	$ (258,746)	$ (245,595)	$ (221,863)
Net loss per share - basic (in dollars per share)	$ (2.73)	$ (2.92)	$ (3.26)
Net loss per share - diluted (in dollars per share)	$ (2.73)	$ (2.92)	$ (3.26)
Weighted-average common shares outstanding - basic (in shares)	94,807,773	84,009,004	68,148,925
Weighted-average common shares outstanding - diluted (in shares)	94,807,773	84,009,004	68,148,925