0001172661-23-001300.txt : 20230214 0001172661-23-001300.hdr.sgml : 20230214 20230214160240 ACCESSION NUMBER: 0001172661-23-001300 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20221231 FILED AS OF DATE: 20230214 DATE AS OF CHANGE: 20230214 EFFECTIVENESS DATE: 20230214 FILER: COMPANY DATA: COMPANY CONFORMED NAME: GREAT POINT PARTNERS LLC CENTRAL INDEX KEY: 0001281446 IRS NUMBER: 000000000 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-11743 FILM NUMBER: 23628583 BUSINESS ADDRESS: STREET 1: 165 MASON STREET, 3RD FLOOR CITY: GREENWICH STATE: CT ZIP: 06830 BUSINESS PHONE: 203 971-3300 MAIL ADDRESS: STREET 1: 165 MASON STREET, 3RD FLOOR CITY: GREENWICH STATE: CT ZIP: 06830 13F-HR 1 primary_doc.xml X0202 13F-HR LIVE false false false 0001281446 XXXXXXXX 12-31-2022 12-31-2022 false GREAT POINT PARTNERS LLC

165 Mason Street, 3rd Floor Greenwich CT 06830

13F HOLDINGS REPORT 028-11743 000158423 801-73834 N Dr. Jeffrey R. Jay, M.D. 203-971-3300 /s/ Dr. Jeffrey R. Jay, M.D. Greenwich CT 02-14-2023 2 42 510185143 1 0001239607 028-12517 JAY JEFFREY R 2 0001832128 028-20398 Yehudai Ortav INFORMATION TABLE 2 infotable.xml ACLARIS THERAPEUTICS INC COM 00461U105 16053692 1019282 SH DFND 1,2 0 1019282 0 ACUMEN PHARMACEUTICALS INC COM 00509G209 6029537 1116581 SH DFND 1,2 0 1116581 0 AEROVATE THERAPEUTICS INC COM 008064107 11090695 378522 SH DFND 1,2 0 378522 0 ALBIREO PHARMA INC COM 01345P106 5775986 267283 SH DFND 1,2 0 267283 0 ALKERMES PLC SHS G01767105 1206814 46185 SH DFND 1,2 0 46185 0 ALPINE IMMUNE SCIENCES INC COM 02083G100 26737227 3637718 SH DFND 1,2 0 3637718 0 AMYLYX PHARMACEUTICALS INC COM 03237H101 7020500 190000 SH DFND 1,2 0 190000 0 ANAPTYSBIO INC COM 032724106 464850 15000 SH DFND 1,2 0 15000 0 CINCOR PHARMA INC COM 17240Y109 12525390 1019153 SH DFND 1,2 0 1019153 0 CYMABAY THERAPEUTICS INC COM 23257D103 9718500 1550000 SH DFND 1,2 0 1550000 0 DAY ONE BIOPHARMACEUTICALS I COM 23954D109 11716586 544451 SH DFND 1,2 0 544451 0 ERASCA INC COM 29479A108 6630767 1538461 SH DFND 1,2 0 1538461 0 EVOLUS INC COM 30052C107 1429371 190329 SH DFND 1,2 0 190329 0 GENERATION BIO CO COM 37148K100 4018570 1022537 SH DFND 1,2 0 1022537 0 GRACELL BIOTECHNOLOGIES INC SPONSORED ADS 38406L103 4513518 1962399 SH DFND 1,2 0 1962399 0 HERON THERAPEUTICS INC COM 427746102 15900403 6360161 SH DFND 1,2 0 6360161 0 IMMUNIC INC COM 4525EP101 885058 632184 SH DFND 1,2 0 632184 0 INTERCEPT PHARMACEUTICALS IN COM 45845P108 6541875 528850 SH DFND 1,2 0 528850 0 IVERIC BIO INC COM 46583P102 17663250 825000 SH DFND 1,2 0 825000 0 JAZZ PHARMACEUTICALS PLC SHS USD G50871105 25489600 160000 SH DFND 1,2 0 160000 0 KALVISTA PHARMACEUTICALS INC COM 483497103 7137215 1055801 SH DFND 1,2 0 1055801 0 LARIMAR THERAPEUTICS INC COM 517125100 5260113 1273635 SH DFND 1,2 0 1273635 0 MIRATI THERAPEUTICS INC COM 60468T105 6026230 133000 SH DFND 1,2 0 133000 0 MOONLAKE IMMUNOTHERAPEUTICS CLASS A ORD 61559X104 6746943 642566 SH DFND 1,2 0 642566 0 NOVOCURE LTD ORD SHS G6674U108 17677350 241000 SH Put DFND 1,2 0 241000 0 OPTINOSE INC COM 68404V100 14605262 7894736 SH DFND 1,2 0 7894736 0 PLIANT THERAPEUTICS INC COM 729139105 25571077 1322870 SH DFND 1,2 0 1322870 0 POINT BIOPHARMA GLOBAL INC COM 730541109 18529569 2541779 SH DFND 1,2 0 2541779 0 PRECISION BIOSCIENCES INC COM 74019P108 4523553 3801305 SH DFND 1,2 0 3801305 0 PTC THERAPEUTICS INC COM 69366J200 11532493 302135 SH DFND 1,2 0 302135 0 RAPT THERAPEUTICS INC COM 75382E109 28444066 1436569 SH DFND 1,2 0 1436569 0 ROCKET PHARMACEUTICALS INC COM 77313F106 8826070 451000 SH Call DFND 1,2 0 451000 0 SAREPTA THERAPEUTICS INC COM 803607100 9459340 73000 SH DFND 1,2 0 73000 0 SEAGEN INC COM 81181C104 20625855 160500 SH DFND 1,2 0 160500 0 TRAVERE THERAPEUTICS INC COM 89422G107 9989250 475000 SH DFND 1,2 0 475000 0 ULTRAGENYX PHARMACEUTICAL IN COM 90400D108 15858759 342300 SH DFND 1,2 0 342300 0 UROGEN PHARMA LTD COM M96088105 4967200 560000 SH DFND 1,2 0 560000 0 VAXCYTE INC COM 92243G108 38360000 800000 SH DFND 1,2 0 800000 0 VENTYX BIOSCIENCES INC COM 92332V107 13138789 400695 SH DFND 1,2 0 400695 0 VERVE THERAPEUTICS INC COM 92539P101 5805000 300000 SH DFND 1,2 0 300000 0 VIKING THERAPEUTICS INC COM 92686J106 12173320 1295034 SH DFND 1,2 0 1295034 0 XENON PHARMACEUTICALS INC COM 98420N105 33515500 850000 SH DFND 1,2 0 850000 0