0001172661-22-002573.txt : 20221114 0001172661-22-002573.hdr.sgml : 20221114 20221114162420 ACCESSION NUMBER: 0001172661-22-002573 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20220930 FILED AS OF DATE: 20221114 DATE AS OF CHANGE: 20221114 EFFECTIVENESS DATE: 20221114 FILER: COMPANY DATA: COMPANY CONFORMED NAME: GREAT POINT PARTNERS LLC CENTRAL INDEX KEY: 0001281446 IRS NUMBER: 000000000 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-11743 FILM NUMBER: 221386068 BUSINESS ADDRESS: STREET 1: 165 MASON STREET, 3RD FLOOR CITY: GREENWICH STATE: CT ZIP: 06830 BUSINESS PHONE: 203 971-3300 MAIL ADDRESS: STREET 1: 165 MASON STREET, 3RD FLOOR CITY: GREENWICH STATE: CT ZIP: 06830 13F-HR 1 primary_doc.xml 13F-HR LIVE false false false 0001281446 XXXXXXXX 09-30-2022 09-30-2022 false GREAT POINT PARTNERS LLC

165 Mason Street, 3rd Floor Greenwich CT 06830

13F HOLDINGS REPORT 028-11743 N Dr. Jeffrey R. Jay, M.D. 203-971-3300 /s/ Dr. Jeffrey R. Jay, M.D. Greenwich CT 11-14-2022 2 40 415311 1 0001239607 028-12517 JAY JEFFREY R 2 0001832128 028-20398 Yehudai Ortav INFORMATION TABLE 2 infotable.xml 89BIO INC COM 282559103 5529 955000 SH DFND 1,2 0 955000 0 ACLARIS THERAPEUTICS INC COM 00461U105 16043 1019282 SH DFND 1,2 0 1019282 0 ACUMEN PHARMACEUTICALS INC COM 00509G209 12036 1200000 SH DFND 1,2 0 1200000 0 AEGLEA BIOTHERAPEUTICS INC COM 00773J103 1315 2500000 SH DFND 1,2 0 2500000 0 ALKERMES PLC SHS G01767105 11332 507500 SH DFND 1,2 0 507500 0 ALPINE IMMUNE SCIENCES INC COM 02083G100 24829 3448521 SH DFND 1,2 0 3448521 0 BRIDGEBIO PHARMA INC COM 10806X102 10437 1050000 SH DFND 1,2 0 1050000 0 CINCOR PHARMA INC COM 17240Y109 9889 301324 SH DFND 1,2 0 301324 0 CYMABAY THERAPEUTICS INC COM 23257D103 2798 799439 SH DFND 1,2 0 799439 0 DAY ONE BIOPHARMACEUTICALS I COM 23954D109 1415 70621 SH DFND 1,2 0 70621 0 GALAPAGOS NV SPON ADR 36315X101 13065 306411 SH DFND 1,2 0 306411 0 GENERATION BIO CO COM 37148K100 4381 825077 SH DFND 1,2 0 825077 0 GRACELL BIOTECHNOLOGIES INC SPONSORED ADS 38406L103 1446 449049 SH DFND 1,2 0 449049 0 HERON THERAPEUTICS INC COM 427746102 23484 5645161 SH DFND 1,2 0 5645161 0 IMMUNOCORE HLDGS PLC ADS 45258D105 3686 78527 SH DFND 1,2 0 78527 0 INTERCEPT PHARMACEUTICALS IN COM 45845P108 1465 105000 SH DFND 1,2 0 105000 0 JAZZ PHARMACEUTICALS PLC SHS USD G50871105 28657 215000 SH DFND 1,2 0 215000 0 KALVISTA PHARMACEUTICALS INC COM 483497103 22515 1551719 SH DFND 1,2 0 1551719 0 LARIMAR THERAPEUTICS INC COM 517125100 3632 1135000 SH DFND 1,2 0 1135000 0 MADRIGAL PHARMACEUTICALS INC COM 558868105 6207 95500 SH DFND 1,2 0 95500 0 MAGENTA THERAPEUTICS INC COM 55910K108 1437 1019091 SH DFND 1,2 0 1019091 0 MILESTONE PHARMACEUTICALS IN COM 59935V107 6200 674656 SH DFND 1,2 0 674656 0 MOONLAKE IMMUNOTHERAPEUTICS CLASS A ORD 61559X104 3818 492000 SH DFND 1,2 0 492000 0 NEKTAR THERAPEUTICS COM 640268108 1433 447820 SH DFND 1,2 0 447820 0 NGM BIOPHARMACEUTICALS INC COM 62921N105 4137 316256 SH DFND 1,2 0 316256 0 PIERIS PHARMACEUTICALS INC COM 720795103 2260 1965449 SH DFND 1,2 0 1965449 0 PLIANT THERAPEUTICS INC COM 729139105 21762 1041737 SH DFND 1,2 0 1041737 0 POINT BIOPHARMA GLOBAL INC COM 730541109 27526 3560984 SH DFND 1,2 0 3560984 0 PRECISION BIOSCIENCES INC COM 74019P108 3524 2710805 SH DFND 1,2 0 2710805 0 RAPT THERAPEUTICS INC COM 75382E109 7579 315000 SH DFND 1,2 0 315000 0 RELMADA THERAPEUTICS INC COM 75955J402 18880 510000 SH DFND 1,2 0 510000 0 REPLIMUNE GROUP INC COM 76029N106 6735 390000 SH DFND 1,2 0 390000 0 SEAGEN INC COM 81181C104 10467 76500 SH DFND 1,2 0 76500 0 SILENCE THERAPEUTICS PLC ADS 82686Q101 692 68915 SH DFND 1,2 0 68915 0 TRAVERE THERAPEUTICS INC COM 89422G107 23805 966108 SH DFND 1,2 0 966108 0 TRICIDA INC COM 89610F101 9118 870000 SH DFND 1,2 0 870000 0 UROGEN PHARMA LTD COM M96088105 7267 873424 SH DFND 1,2 0 873424 0 VAXCYTE INC COM 92243G108 14400 600000 SH DFND 1,2 0 600000 0 VENTYX BIOSCIENCES INC COM 92332V107 9425 269967 SH DFND 1,2 0 269967 0 XENON PHARMACEUTICALS INC COM 98420N105 30685 850000 SH DFND 1,2 0 850000 0