X0306 4 2013-04-01 0 0001368993 WaferGen Bio-systems, Inc. WGBS 0001540081 Pesce Joseph F C/O GREAT POINT PARTNERS, LLC 165 MASON STREET, 3RD FLOOR GREENWICH CT 06870 1 0 0 0 0001281446 GREAT POINT PARTNERS LLC 165 MASON STREET, 3RD FLOOR GREENWICH CT 06870 0 0 0 1 See Footnote 2 Stock Option (right to buy) 0.056 2013-04-01 4 A 0 150000 0 A 2020-04-01 Common Stock 150000 150000 D Twenty-five percent of the shares subject to the option shall vest on each of June 30, 2013, September 30, 2013, December 31, 2013 and March 31, 2014 Mr. Pesce is holding such options solely as a nominee for Great Point Partners LLC, which manages the securities for the benefit of each of Biomedical Value Fund, LP, Biomedical Offshore Value Fund, Ltd, Biomedical Institutional Value Fund, L.P., Lyrical Multi-Manager Fund, LP, Lyrical Multi-Manager Offshore Fund, Ltd, Class D Series of GEF-PS, LP, David J. Morrison and WS Investments III, LLC. Mr. Pesce disclaims beneficial ownership of such securities except to the extent of his pecuniary interests therein. See Footnote 2 /s/ Ron Panzier, CFO, Great Point Partners, LLC 2013-04-03 /s/ Joseph F. Pesce 2013-04-03