0000930413-19-000592.txt : 20190215 0000930413-19-000592.hdr.sgml : 20190215 20190214210125 ACCESSION NUMBER: 0000930413-19-000592 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20181231 FILED AS OF DATE: 20190215 DATE AS OF CHANGE: 20190214 EFFECTIVENESS DATE: 20190215 FILER: COMPANY DATA: COMPANY CONFORMED NAME: GREAT POINT PARTNERS LLC CENTRAL INDEX KEY: 0001281446 IRS NUMBER: 000000000 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-11743 FILM NUMBER: 19609561 BUSINESS ADDRESS: STREET 1: 165 MASON STREET, 3RD FLOOR CITY: GREENWICH STATE: CT ZIP: 06830 BUSINESS PHONE: 203 971-3300 MAIL ADDRESS: STREET 1: 165 MASON STREET, 3RD FLOOR CITY: GREENWICH STATE: CT ZIP: 06830 13F-HR 1 primary_doc.xml 13F-HR LIVE false false false 0001281446 XXXXXXXX 12-31-2018 12-31-2018 false GREAT POINT PARTNERS LLC

165 MASON STREET, 3RD FLOOR GREENWICH CT 06830

13F HOLDINGS REPORT 028-11743 N Dr. Jeffrey R. Jay, M.D 203-971-3300 /s/ Dr. Jeffrey R. Jay, M.D Greenwich CT 02-14-2019 2 42 791189 1 0001239607 028-12517 JAY JEFFREY R 2 0001397513 028-13262 KROIN DAVID INFORMATION TABLE 2 infotable.xml AMAG PHARMACEUTICALS INC COM 00163U106 10097 664681 SH DFND 1,2 664681 0 0 ACADIA PHARMACEUTICALS INC COM 004225108 44504 2752256 SH DFND 1,2 2752256 0 0 ACCELERON PHARMA INC COM 00434H108 45143 1036575 SH DFND 1,2 1036575 0 0 ALNYLAM PHARMACEUTICALS INC COM 02043Q107 2931 40197 SH DFND 1,2 40197 0 0 ARGENX SE SPONSORED ADR 04016X101 1777 18500 SH DFND 1,2 18500 0 0 ARRAY BIOPHARMA INC COM 04269X105 26363 1850000 SH DFND 1,2 1850000 0 0 BIOCRYST PHARMACEUTICALS COM 09058V103 61512 7622256 SH DFND 1,2 7622256 0 0 CYMABAY THERAPEUTICS INC COM 23257D103 11164 1418489 SH DFND 1,2 1418489 0 0 CYTOKINETICS INC COM 23282W605 20055 3173288 SH DFND 1,2 3173288 0 0 ENANTA PHARMACEUTICALS INC COM 29251M106 10163 143481 SH DFND 1,2 143481 0 0 FIVE PRIME THERAPEUTICS INC COM 33830X104 22305 2398409 SH DFND 1,2 2398409 0 0 GLOBAL BLOOD THERAPEUTICS INC COM 37890U108 48439 1180000 SH DFND 1,2 1180000 0 0 INTERCEPT PHARMACEUTICALS INC COM 45845P108 20158 200000 SH Put DFND 1,2 200000 0 0 INTRA CELLULAR THERAPIES INC COM 46116X101 2278 200000 SH Put DFND 1,2 200000 0 0 INTRA CELLULAR THERAPIES INC COM 46116X101 2278 200000 SH Put DFND 1,2 200000 0 0 IOVANCE BIOTHERAPEUTICS INC COM 462260100 49271 5567348 SH DFND 1,2 5567348 0 0 KRYSTAL BIOTECH INC COM 501147102 10226 492100 SH DFND 1,2 492100 0 0 KURA ONCOLOGY INC COM 50127T109 38884 2769527 SH DFND 1,2 2769527 0 0 MADRIGAL PHARMACEUTICALS INC COM 558868105 3100 27500 SH DFND 1,2 27500 0 0 MENLO THERAPEUTICS INC COM 586858102 9082 2204407 SH DFND 1,2 2204407 0 0 MILLENDO THERAPEUTICS INC COM 60040X103 10240 1288093 SH DFND 1,2 1288093 0 0 NOVAVAX INC COM 670002104 4600 2500000 SH Call DFND 1,2 2500000 0 0 NOVAVAX INC COM 670002104 3680 2000000 SH Call DFND 1,2 2000000 0 0 PTC THERAPEUTICS INC COM 69366J200 42042 1225000 SH DFND 1,2 1225000 0 0 PROTAGONIST THERAPEUTICS INC COM 74366E102 6431 955618 SH DFND 1,2 955618 0 0 PROTEOSTASIS THERAPEUTICS INC COM 74373B109 9867 3045423 SH DFND 1,2 3045423 0 0 PUMA BIOTECHNOLOGY INC COM 74587V107 28077 1379700 SH DFND 1,2 1379700 0 0 SAGE THERAPEUTICS INC COM 78667J108 2491 26000 SH Put DFND 1,2 26000 0 0 SAGE THERAPEUTICS INC COM 78667J108 2491 26000 SH Call DFND 1,2 26000 0 0 SAVARA INC CMN COM 805111101 13771 1819195 SH DFND 1,2 1819195 0 0 SPARK THERAPEUTICS INC COM 84652J103 24682 630600 SH DFND 1,2 630600 0 0 STREAMLINE HEALTH SOLUTIONS COM 86323X106 105 130137 SH DFND 1,2 130137 0 0 SUNESIS PHARMACEUTICALS INC COM 867328700 132 317962 SH DFND 1,2 317962 0 0 TG THERAPEUTICS INC COM 88322Q108 12300 3000000 SH DFND 1,2 3000000 0 0 UNITED THERAPEUTICS CORP DEL COM 91307C102 38202 350800 SH DFND 1,2 350800 0 0 VERTEX PHARMACEUTICALS INC COM 92532F100 33142 200000 SH Put DFND 1,2 200000 0 0 VOYAGER THERAPEUTICS INC COM 92915B106 3432 365132 SH DFND 1,2 365132 0 0 ZAFGEN INC COM 98885E103 17812 3598392 SH DFND 1,2 3598392 0 0 ZOGENIX INC COM 98978L204 36460 1000000 SH DFND 1,2 1000000 0 0 OSMOTICA PHARMACEUTICALS PLC SHS G6S41R101 11625 1500000 SH DFND 1,2 1500000 0 0 FOAMIX PHARMACEUTICALS LTD SHS M46135105 14531 4047561 SH DFND 1,2 4047561 0 0 AUDENTES THERAPEUTICS INC COM 05070R104 35346 1657873 SH DFND 1,2 1657873 0 0