<?xml version="1.0" encoding="UTF-8"?>

<!--XBRL Document Created with the Workiva Platform-->
<!--Copyright 2026 Workiva-->
<!--r:c331f3ad-611b-4d8f-aaeb-e22a8774ccfa,g:14ba4c5f-f4ee-4313-9ac9-19a168c3ee28-->
<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
  <link:roleRef roleURI="http://www.htgc.com/role/CONSOLIDATEDSTATEMENTSOFASSETSANDLIABILITIES" xlink:type="simple" xlink:href="htgc-20251231.xsd#CONSOLIDATEDSTATEMENTSOFASSETSANDLIABILITIES"/>
  <link:calculationLink xlink:role="http://www.htgc.com/role/CONSOLIDATEDSTATEMENTSOFASSETSANDLIABILITIES" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_b6f7d57e-496f-4fd6-9869-5cea08b6f3eb" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StockholdersEquity"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockValue_7e6d8442-2276-48ce-aed8-823e76027618" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CommonStockValue"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_b6f7d57e-496f-4fd6-9869-5cea08b6f3eb" xlink:to="loc_us-gaap_CommonStockValue_7e6d8442-2276-48ce-aed8-823e76027618" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdditionalPaidInCapital_05a1d01a-3e3f-4b0b-826d-ae87aab55e6d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AdditionalPaidInCapital"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_b6f7d57e-496f-4fd6-9869-5cea08b6f3eb" xlink:to="loc_us-gaap_AdditionalPaidInCapital_05a1d01a-3e3f-4b0b-826d-ae87aab55e6d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetainedEarningsAccumulatedDeficit_64cb3092-277c-4c08-bfaf-46863ffc0495" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RetainedEarningsAccumulatedDeficit"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_b6f7d57e-496f-4fd6-9869-5cea08b6f3eb" xlink:to="loc_us-gaap_RetainedEarningsAccumulatedDeficit_64cb3092-277c-4c08-bfaf-46863ffc0495" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Assets_d1c4dcfa-6340-4d02-9561-71f758c2eb60" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_Assets"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_1027326f-edd5-4542-be24-416db9bd85cd" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_d1c4dcfa-6340-4d02-9561-71f758c2eb60" xlink:to="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_1027326f-edd5-4542-be24-416db9bd85cd" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentOwnedAtFairValue_ee01ebb0-3c4d-493e-a0ca-8636f1fb47d4" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InvestmentOwnedAtFairValue"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_d1c4dcfa-6340-4d02-9561-71f758c2eb60" xlink:to="loc_us-gaap_InvestmentOwnedAtFairValue_ee01ebb0-3c4d-493e-a0ca-8636f1fb47d4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseRightOfUseAsset_e0d6cb2e-3a14-4e5e-a644-4629099dd65a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingLeaseRightOfUseAsset"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_d1c4dcfa-6340-4d02-9561-71f758c2eb60" xlink:to="loc_us-gaap_OperatingLeaseRightOfUseAsset_e0d6cb2e-3a14-4e5e-a644-4629099dd65a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestReceivable_a36f3bc9-612a-419e-97b3-949876d85075" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InterestReceivable"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_d1c4dcfa-6340-4d02-9561-71f758c2eb60" xlink:to="loc_us-gaap_InterestReceivable_a36f3bc9-612a-419e-97b3-949876d85075" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedCash_0046bd3b-44ce-40ab-a9d7-40c2047977e8" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RestrictedCash"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_d1c4dcfa-6340-4d02-9561-71f758c2eb60" xlink:to="loc_us-gaap_RestrictedCash_0046bd3b-44ce-40ab-a9d7-40c2047977e8" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAssets_76fd0eee-7fe7-4f75-b2b1-f75743bf3e72" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherAssets"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_d1c4dcfa-6340-4d02-9561-71f758c2eb60" xlink:to="loc_us-gaap_OtherAssets_76fd0eee-7fe7-4f75-b2b1-f75743bf3e72" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashHeldInForeignCurrency_b175e59b-2b1a-4373-917e-885cbb658903" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CashHeldInForeignCurrency"/>
    <link:calculationArc order="7" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_d1c4dcfa-6340-4d02-9561-71f758c2eb60" xlink:to="loc_us-gaap_CashHeldInForeignCurrency_b175e59b-2b1a-4373-917e-885cbb658903" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Liabilities_467aad20-2573-4cab-8e77-01bc7875d570" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_Liabilities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebt_aab0ed6b-d3c3-4472-8592-6e96674307e5" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LongTermDebt"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_467aad20-2573-4cab-8e77-01bc7875d570" xlink:to="loc_us-gaap_LongTermDebt_aab0ed6b-d3c3-4472-8592-6e96674307e5" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiability_1841d44f-8982-49a7-b0bb-4ead71a48ee0" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingLeaseLiability"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_467aad20-2573-4cab-8e77-01bc7875d570" xlink:to="loc_us-gaap_OperatingLeaseLiability_1841d44f-8982-49a7-b0bb-4ead71a48ee0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesCurrentAndNoncurrent_2208832b-0f50-414d-aab9-79009ccea6d7" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccountsPayableAndAccruedLiabilitiesCurrentAndNoncurrent"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_467aad20-2573-4cab-8e77-01bc7875d570" xlink:to="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesCurrentAndNoncurrent_2208832b-0f50-414d-aab9-79009ccea6d7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesAndStockholdersEquity_41a0ef9d-8b17-41a7-8c7c-8018e22fcee1" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LiabilitiesAndStockholdersEquity"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_5dc9f163-c505-49a2-8ef0-dfc4d2d665ed" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StockholdersEquity"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_41a0ef9d-8b17-41a7-8c7c-8018e22fcee1" xlink:to="loc_us-gaap_StockholdersEquity_5dc9f163-c505-49a2-8ef0-dfc4d2d665ed" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Liabilities_9685c97b-0ade-4aed-b903-cd21a6892e28" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_Liabilities"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_41a0ef9d-8b17-41a7-8c7c-8018e22fcee1" xlink:to="loc_us-gaap_Liabilities_9685c97b-0ade-4aed-b903-cd21a6892e28" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingencies_cb379b91-daea-4768-a5ca-df13709d4366" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CommitmentsAndContingencies"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_41a0ef9d-8b17-41a7-8c7c-8018e22fcee1" xlink:to="loc_us-gaap_CommitmentsAndContingencies_cb379b91-daea-4768-a5ca-df13709d4366" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.htgc.com/role/CONSOLIDATEDSTATEMENTSOFOPERATIONS" xlink:type="simple" xlink:href="htgc-20251231.xsd#CONSOLIDATEDSTATEMENTSOFOPERATIONS"/>
  <link:calculationLink xlink:role="http://www.htgc.com/role/CONSOLIDATEDSTATEMENTSOFOPERATIONS" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_8dec3a74-44fe-4dfa-8719-2d5abb94947a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetIncomeLoss"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentCompanyRealizedAndUnrealizedGainLossOnInvestmentAndForeignCurrency_c8766cbe-c58e-45a7-bc2b-6eb05dc55200" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InvestmentCompanyRealizedAndUnrealizedGainLossOnInvestmentAndForeignCurrency"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetIncomeLoss_8dec3a74-44fe-4dfa-8719-2d5abb94947a" xlink:to="loc_us-gaap_InvestmentCompanyRealizedAndUnrealizedGainLossOnInvestmentAndForeignCurrency_c8766cbe-c58e-45a7-bc2b-6eb05dc55200" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetInvestmentIncome_a4818a2b-ea9f-4f8f-bdd1-fd19e31be6a4" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetInvestmentIncome"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetIncomeLoss_8dec3a74-44fe-4dfa-8719-2d5abb94947a" xlink:to="loc_us-gaap_NetInvestmentIncome_a4818a2b-ea9f-4f8f-bdd1-fd19e31be6a4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetInvestmentIncome_92992ba2-99c5-4611-9fe4-88299ab91468" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetInvestmentIncome"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GrossInvestmentIncomeOperating_efc59a45-d3af-4dee-b9c0-e8474c56244b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_GrossInvestmentIncomeOperating"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetInvestmentIncome_92992ba2-99c5-4611-9fe4-88299ab91468" xlink:to="loc_us-gaap_GrossInvestmentIncomeOperating_efc59a45-d3af-4dee-b9c0-e8474c56244b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_htgc_OperatingExpensesNet_c5d5b623-3e96-4ade-824d-19ededde1f4f" xlink:href="htgc-20251231.xsd#htgc_OperatingExpensesNet"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetInvestmentIncome_92992ba2-99c5-4611-9fe4-88299ab91468" xlink:to="loc_htgc_OperatingExpensesNet_c5d5b623-3e96-4ade-824d-19ededde1f4f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestAndDividendIncomeOperating_2fdfd8f2-fcf1-46ad-9d6e-adfb06e31b56" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InterestAndDividendIncomeOperating"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestAndDividendIncomeOperatingPaidInCash_775caee2-6640-4259-85ed-fb4aa0386ff8" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InterestAndDividendIncomeOperatingPaidInCash"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InterestAndDividendIncomeOperating_2fdfd8f2-fcf1-46ad-9d6e-adfb06e31b56" xlink:to="loc_us-gaap_InterestAndDividendIncomeOperatingPaidInCash_775caee2-6640-4259-85ed-fb4aa0386ff8" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestIncomeOperatingPaidInKind_e9de355d-7632-4a92-a515-cd6a50e71814" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InterestIncomeOperatingPaidInKind"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InterestAndDividendIncomeOperating_2fdfd8f2-fcf1-46ad-9d6e-adfb06e31b56" xlink:to="loc_us-gaap_InterestIncomeOperatingPaidInKind_e9de355d-7632-4a92-a515-cd6a50e71814" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_htgc_RealizedInvestmentGainsLossAndGainLossOnExtinguishmentOfDebt_98175426-c9b1-414e-bc48-2889e3f293df" xlink:href="htgc-20251231.xsd#htgc_RealizedInvestmentGainsLossAndGainLossOnExtinguishmentOfDebt"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_959391d8-5136-4b69-809b-874095b4a279" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_GainsLossesOnExtinguishmentOfDebt"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_htgc_RealizedInvestmentGainsLossAndGainLossOnExtinguishmentOfDebt_98175426-c9b1-414e-bc48-2889e3f293df" xlink:to="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_959391d8-5136-4b69-809b-874095b4a279" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RealizedInvestmentGainsLosses_ce577981-78de-4564-bc28-79a190884dd0" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RealizedInvestmentGainsLosses"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_htgc_RealizedInvestmentGainsLossAndGainLossOnExtinguishmentOfDebt_98175426-c9b1-414e-bc48-2889e3f293df" xlink:to="loc_us-gaap_RealizedInvestmentGainsLosses_ce577981-78de-4564-bc28-79a190884dd0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GrossInvestmentIncomeOperating_7e63efe7-5411-46b7-be5e-613a181ea480" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_GrossInvestmentIncomeOperating"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestAndDividendIncomeOperating_cbfd0c1c-4b66-4c68-ba47-0e81a1494dad" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InterestAndDividendIncomeOperating"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_GrossInvestmentIncomeOperating_7e63efe7-5411-46b7-be5e-613a181ea480" xlink:to="loc_us-gaap_InterestAndDividendIncomeOperating_cbfd0c1c-4b66-4c68-ba47-0e81a1494dad" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FeeIncome_0ae580f3-e6c5-4f92-a0e4-e8c3c42d93a4" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FeeIncome"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_GrossInvestmentIncomeOperating_7e63efe7-5411-46b7-be5e-613a181ea480" xlink:to="loc_us-gaap_FeeIncome_0ae580f3-e6c5-4f92-a0e4-e8c3c42d93a4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_htgc_EmployeeCompensation_e55ebfd4-39fc-4beb-9b62-c22b43b0ad4e" xlink:href="htgc-20251231.xsd#htgc_EmployeeCompensation"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LaborAndRelatedExpense_e9f3f01f-24de-49da-af58-aae64e88f749" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LaborAndRelatedExpense"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_htgc_EmployeeCompensation_e55ebfd4-39fc-4beb-9b62-c22b43b0ad4e" xlink:to="loc_us-gaap_LaborAndRelatedExpense_e9f3f01f-24de-49da-af58-aae64e88f749" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeBenefitsAndShareBasedCompensation_a1e65a7d-f185-459b-b299-70c831c05ae4" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_EmployeeBenefitsAndShareBasedCompensation"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_htgc_EmployeeCompensation_e55ebfd4-39fc-4beb-9b62-c22b43b0ad4e" xlink:to="loc_us-gaap_EmployeeBenefitsAndShareBasedCompensation_a1e65a7d-f185-459b-b299-70c831c05ae4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentCompanyRealizedAndUnrealizedGainLossOnInvestmentAndForeignCurrency_ba171cb2-7b32-4df1-8e11-42450feade10" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InvestmentCompanyRealizedAndUnrealizedGainLossOnInvestmentAndForeignCurrency"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_UnrealizedGainLossOnInvestments_a578f1b3-943f-47ee-9733-e2e1efea2efc" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_UnrealizedGainLossOnInvestments"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InvestmentCompanyRealizedAndUnrealizedGainLossOnInvestmentAndForeignCurrency_ba171cb2-7b32-4df1-8e11-42450feade10" xlink:to="loc_us-gaap_UnrealizedGainLossOnInvestments_a578f1b3-943f-47ee-9733-e2e1efea2efc" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_htgc_RealizedInvestmentGainsLossAndGainLossOnExtinguishmentOfDebt_bdf28a50-8b18-4556-8e19-72089f71d112" xlink:href="htgc-20251231.xsd#htgc_RealizedInvestmentGainsLossAndGainLossOnExtinguishmentOfDebt"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InvestmentCompanyRealizedAndUnrealizedGainLossOnInvestmentAndForeignCurrency_ba171cb2-7b32-4df1-8e11-42450feade10" xlink:to="loc_htgc_RealizedInvestmentGainsLossAndGainLossOnExtinguishmentOfDebt_bdf28a50-8b18-4556-8e19-72089f71d112" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingExpenses_64d2e9a6-9d35-434b-be28-6946808b3d65" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingExpenses"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentIncomeOperatingTaxExpenseBenefit_53da02c3-54b1-4d4f-9951-8df1e1251e28" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InvestmentIncomeOperatingTaxExpenseBenefit"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingExpenses_64d2e9a6-9d35-434b-be28-6946808b3d65" xlink:to="loc_us-gaap_InvestmentIncomeOperatingTaxExpenseBenefit_53da02c3-54b1-4d4f-9951-8df1e1251e28" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtRelatedCommitmentFeesAndDebtIssuanceCosts_bbffaaf9-e2cd-480b-a24c-a7812e84ff67" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DebtRelatedCommitmentFeesAndDebtIssuanceCosts"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingExpenses_64d2e9a6-9d35-434b-be28-6946808b3d65" xlink:to="loc_us-gaap_DebtRelatedCommitmentFeesAndDebtIssuanceCosts_bbffaaf9-e2cd-480b-a24c-a7812e84ff67" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestExpenseDebt_241613f6-7eab-4ea6-a1f4-dac7707f2bc5" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InterestExpenseDebt"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingExpenses_64d2e9a6-9d35-434b-be28-6946808b3d65" xlink:to="loc_us-gaap_InterestExpenseDebt_241613f6-7eab-4ea6-a1f4-dac7707f2bc5" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GeneralAndAdministrativeExpense_d39b2aa0-13e5-4eaa-ac0f-1b42734f146b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_GeneralAndAdministrativeExpense"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingExpenses_64d2e9a6-9d35-434b-be28-6946808b3d65" xlink:to="loc_us-gaap_GeneralAndAdministrativeExpense_d39b2aa0-13e5-4eaa-ac0f-1b42734f146b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_htgc_EmployeeCompensation_bc95ee18-617d-4db8-8d6f-33f28c7c3d4a" xlink:href="htgc-20251231.xsd#htgc_EmployeeCompensation"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingExpenses_64d2e9a6-9d35-434b-be28-6946808b3d65" xlink:to="loc_htgc_EmployeeCompensation_bc95ee18-617d-4db8-8d6f-33f28c7c3d4a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_htgc_OperatingExpensesNet_0dec1f2a-18dc-4fa3-a369-698201aedf9f" xlink:href="htgc-20251231.xsd#htgc_OperatingExpensesNet"/>
    <link:loc xlink:type="locator" xlink:label="loc_htgc_ExpensesAllocatedToAdviserSubsidiary1_12186178-100b-432a-85c2-8e550c57e0cb" xlink:href="htgc-20251231.xsd#htgc_ExpensesAllocatedToAdviserSubsidiary1"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_htgc_OperatingExpensesNet_0dec1f2a-18dc-4fa3-a369-698201aedf9f" xlink:to="loc_htgc_ExpensesAllocatedToAdviserSubsidiary1_12186178-100b-432a-85c2-8e550c57e0cb" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingExpenses_f6266707-6c76-4ec2-8389-f67a0f988e26" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingExpenses"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_htgc_OperatingExpensesNet_0dec1f2a-18dc-4fa3-a369-698201aedf9f" xlink:to="loc_us-gaap_OperatingExpenses_f6266707-6c76-4ec2-8389-f67a0f988e26" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.htgc.com/role/CONSOLIDATEDSTATEMENTSOFCASHFLOWS" xlink:type="simple" xlink:href="htgc-20251231.xsd#CONSOLIDATEDSTATEMENTSOFCASHFLOWS"/>
  <link:calculationLink xlink:role="http://www.htgc.com/role/CONSOLIDATEDSTATEMENTSOFCASHFLOWS" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_e82c74ab-10ec-4faf-b48f-a89762012703" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireProductiveAssets_0a89c9d5-699d-4b78-958c-3ae597ef8c20" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PaymentsToAcquireProductiveAssets"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_e82c74ab-10ec-4faf-b48f-a89762012703" xlink:to="loc_us-gaap_PaymentsToAcquireProductiveAssets_0a89c9d5-699d-4b78-958c-3ae597ef8c20" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_b4a80c1c-d5af-4223-b251-3b71091256bd" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_d8f3bf11-64c1-4a3d-93ea-6750b7fa4cf2" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetIncomeLoss"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_b4a80c1c-d5af-4223-b251-3b71091256bd" xlink:to="loc_us-gaap_NetIncomeLoss_d8f3bf11-64c1-4a3d-93ea-6750b7fa4cf2" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsForPurchaseOfInvestmentOperatingActivity_6c1a1bee-9ab4-47e1-9538-fc54b76bbcc6" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PaymentsForPurchaseOfInvestmentOperatingActivity"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_b4a80c1c-d5af-4223-b251-3b71091256bd" xlink:to="loc_us-gaap_PaymentsForPurchaseOfInvestmentOperatingActivity_6c1a1bee-9ab4-47e1-9538-fc54b76bbcc6" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_htgc_FundingAssignedToAdviserFunds_47ab4057-b9f2-4cff-a139-09e78a60a2e4" xlink:href="htgc-20251231.xsd#htgc_FundingAssignedToAdviserFunds"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_b4a80c1c-d5af-4223-b251-3b71091256bd" xlink:to="loc_htgc_FundingAssignedToAdviserFunds_47ab4057-b9f2-4cff-a139-09e78a60a2e4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromDispositionOfInvestmentOperatingActivity_ccdadb37-dedb-45cc-85c9-e8e781d73f50" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ProceedsFromDispositionOfInvestmentOperatingActivity"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_b4a80c1c-d5af-4223-b251-3b71091256bd" xlink:to="loc_us-gaap_ProceedsFromDispositionOfInvestmentOperatingActivity_ccdadb37-dedb-45cc-85c9-e8e781d73f50" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_htgc_ProceedsFromTheSaleOfDebtInvestments_2896d5f8-d466-4179-a888-272d243db207" xlink:href="htgc-20251231.xsd#htgc_ProceedsFromTheSaleOfDebtInvestments"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_b4a80c1c-d5af-4223-b251-3b71091256bd" xlink:to="loc_htgc_ProceedsFromTheSaleOfDebtInvestments_2896d5f8-d466-4179-a888-272d243db207" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_htgc_ProceedsFromDispositionOfInvestmentEquityAndWarrantsInvestmentsOperatingActivity_1d80c1a2-79bd-476e-8b9c-54a574e945c5" xlink:href="htgc-20251231.xsd#htgc_ProceedsFromDispositionOfInvestmentEquityAndWarrantsInvestmentsOperatingActivity"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_b4a80c1c-d5af-4223-b251-3b71091256bd" xlink:to="loc_htgc_ProceedsFromDispositionOfInvestmentEquityAndWarrantsInvestmentsOperatingActivity_1d80c1a2-79bd-476e-8b9c-54a574e945c5" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_UnrealizedGainLossInvestmentDerivativeAndForeignCurrencyTransactionPriceChangeOperatingBeforeTax_18701958-315e-4b71-bd0d-0cce787a4f7c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_UnrealizedGainLossInvestmentDerivativeAndForeignCurrencyTransactionPriceChangeOperatingBeforeTax"/>
    <link:calculationArc order="7" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_b4a80c1c-d5af-4223-b251-3b71091256bd" xlink:to="loc_us-gaap_UnrealizedGainLossInvestmentDerivativeAndForeignCurrencyTransactionPriceChangeOperatingBeforeTax_18701958-315e-4b71-bd0d-0cce787a4f7c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RealizedGainLossInvestmentAndDerivativeOperatingAfterTax_7ac031bf-d86d-42d7-bcfb-f832a070084f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RealizedGainLossInvestmentAndDerivativeOperatingAfterTax"/>
    <link:calculationArc order="8" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_b4a80c1c-d5af-4223-b251-3b71091256bd" xlink:to="loc_us-gaap_RealizedGainLossInvestmentAndDerivativeOperatingAfterTax_7ac031bf-d86d-42d7-bcfb-f832a070084f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_htgc_PaymentsForDerivativeInstrumentOperatingActivities_4de54cd4-087c-4802-96d5-bd5a74d2dca5" xlink:href="htgc-20251231.xsd#htgc_PaymentsForDerivativeInstrumentOperatingActivities"/>
    <link:calculationArc order="9" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_b4a80c1c-d5af-4223-b251-3b71091256bd" xlink:to="loc_htgc_PaymentsForDerivativeInstrumentOperatingActivities_4de54cd4-087c-4802-96d5-bd5a74d2dca5" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestIncomeOperatingPaidInKind_e8a62f44-d629-4536-ae7f-c993bb332e79" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InterestIncomeOperatingPaidInKind"/>
    <link:calculationArc order="10" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_b4a80c1c-d5af-4223-b251-3b71091256bd" xlink:to="loc_us-gaap_InterestIncomeOperatingPaidInKind_e8a62f44-d629-4536-ae7f-c993bb332e79" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccretionAmortizationOfDiscountsAndPremiumsInvestments_c4b5ba0f-b0fc-47b2-8302-ae09d1965610" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccretionAmortizationOfDiscountsAndPremiumsInvestments"/>
    <link:calculationArc order="11" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_b4a80c1c-d5af-4223-b251-3b71091256bd" xlink:to="loc_us-gaap_AccretionAmortizationOfDiscountsAndPremiumsInvestments_c4b5ba0f-b0fc-47b2-8302-ae09d1965610" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_htgc_AccretionAmortizationOfDiscountsAndPremiumsInvestmentsConvertibleNotes_605d29a2-0c73-40f4-9ddc-28aee5e28973" xlink:href="htgc-20251231.xsd#htgc_AccretionAmortizationOfDiscountsAndPremiumsInvestmentsConvertibleNotes"/>
    <link:calculationArc order="12" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_b4a80c1c-d5af-4223-b251-3b71091256bd" xlink:to="loc_htgc_AccretionAmortizationOfDiscountsAndPremiumsInvestmentsConvertibleNotes_605d29a2-0c73-40f4-9ddc-28aee5e28973" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_9f5fb4aa-8274-486e-8774-b58f1ea22913" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_GainsLossesOnExtinguishmentOfDebt"/>
    <link:calculationArc order="13" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_b4a80c1c-d5af-4223-b251-3b71091256bd" xlink:to="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_9f5fb4aa-8274-486e-8774-b58f1ea22913" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_htgc_AccretionOfLoanExitFees_1cd4a0ac-abf3-4909-aee1-09f187bb0cdc" xlink:href="htgc-20251231.xsd#htgc_AccretionOfLoanExitFees"/>
    <link:calculationArc order="14" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_b4a80c1c-d5af-4223-b251-3b71091256bd" xlink:to="loc_htgc_AccretionOfLoanExitFees_1cd4a0ac-abf3-4909-aee1-09f187bb0cdc" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_htgc_ChangeInLoanIncomeNetOfCollections_f5158a30-bf27-4d81-9715-c034873ac8e0" xlink:href="htgc-20251231.xsd#htgc_ChangeInLoanIncomeNetOfCollections"/>
    <link:calculationArc order="15" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_b4a80c1c-d5af-4223-b251-3b71091256bd" xlink:to="loc_htgc_ChangeInLoanIncomeNetOfCollections_f5158a30-bf27-4d81-9715-c034873ac8e0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_htgc_UnearnedFeesRelatedToUnfundedCommitments_9ab26692-9cb8-4b56-93bf-9b0142e5fec3" xlink:href="htgc-20251231.xsd#htgc_UnearnedFeesRelatedToUnfundedCommitments"/>
    <link:calculationArc order="16" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_b4a80c1c-d5af-4223-b251-3b71091256bd" xlink:to="loc_htgc_UnearnedFeesRelatedToUnfundedCommitments_9ab26692-9cb8-4b56-93bf-9b0142e5fec3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AmortizationOfFinancingCostsAndDiscounts_d6e8508c-ab55-432f-9cf8-336cf3478de6" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AmortizationOfFinancingCostsAndDiscounts"/>
    <link:calculationArc order="17" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_b4a80c1c-d5af-4223-b251-3b71091256bd" xlink:to="loc_us-gaap_AmortizationOfFinancingCostsAndDiscounts_d6e8508c-ab55-432f-9cf8-336cf3478de6" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DepreciationAndAmortization_0ae6cc63-631f-4019-b9c5-b5bf11c17bf5" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DepreciationAndAmortization"/>
    <link:calculationArc order="18" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_b4a80c1c-d5af-4223-b251-3b71091256bd" xlink:to="loc_us-gaap_DepreciationAndAmortization_0ae6cc63-631f-4019-b9c5-b5bf11c17bf5" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensation_a25dd241-a971-4dba-a697-fc912abee6af" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensation"/>
    <link:calculationArc order="19" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_b4a80c1c-d5af-4223-b251-3b71091256bd" xlink:to="loc_us-gaap_ShareBasedCompensation_a25dd241-a971-4dba-a697-fc912abee6af" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccruedInterestReceivableNet_39dc16fc-17b5-4fcb-a54b-fd13a92d0142" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncreaseDecreaseInAccruedInterestReceivableNet"/>
    <link:calculationArc order="20" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_b4a80c1c-d5af-4223-b251-3b71091256bd" xlink:to="loc_us-gaap_IncreaseDecreaseInAccruedInterestReceivableNet_39dc16fc-17b5-4fcb-a54b-fd13a92d0142" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInOtherOperatingAssets_019b8e22-1833-776c-8654-2f30f9f1869e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncreaseDecreaseInOtherOperatingAssets"/>
    <link:calculationArc order="21" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_b4a80c1c-d5af-4223-b251-3b71091256bd" xlink:to="loc_us-gaap_IncreaseDecreaseInOtherOperatingAssets_019b8e22-1833-776c-8654-2f30f9f1869e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccruedLiabilities_019b8e22-1833-755f-980e-8c8e766f879c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncreaseDecreaseInAccruedLiabilities"/>
    <link:calculationArc order="22" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_b4a80c1c-d5af-4223-b251-3b71091256bd" xlink:to="loc_us-gaap_IncreaseDecreaseInAccruedLiabilities_019b8e22-1833-755f-980e-8c8e766f879c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_3ad67415-f63d-466d-90e9-9ada60489005" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_htgc_PaymentOfFeesForCreditFacilities_3edf351e-8a5c-4417-8a96-22d981e03578" xlink:href="htgc-20251231.xsd#htgc_PaymentOfFeesForCreditFacilities"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_3ad67415-f63d-466d-90e9-9ada60489005" xlink:to="loc_htgc_PaymentOfFeesForCreditFacilities_3edf351e-8a5c-4417-8a96-22d981e03578" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromIssuanceOfCommonStock_958ca098-b78a-46e6-bf20-ebf6b36cbe3a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ProceedsFromIssuanceOfCommonStock"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_3ad67415-f63d-466d-90e9-9ada60489005" xlink:to="loc_us-gaap_ProceedsFromIssuanceOfCommonStock_958ca098-b78a-46e6-bf20-ebf6b36cbe3a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsForRepurchaseOfCommonStock_d83c8a48-3447-4487-94b3-bb5e9f760aea" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PaymentsForRepurchaseOfCommonStock"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_3ad67415-f63d-466d-90e9-9ada60489005" xlink:to="loc_us-gaap_PaymentsForRepurchaseOfCommonStock_d83c8a48-3447-4487-94b3-bb5e9f760aea" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsOfDebtIssuanceCosts_884b3712-ac68-49fb-8c98-fb1d2c904159" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PaymentsOfDebtIssuanceCosts"/>
    <link:calculationArc order="4" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_3ad67415-f63d-466d-90e9-9ada60489005" xlink:to="loc_us-gaap_PaymentsOfDebtIssuanceCosts_884b3712-ac68-49fb-8c98-fb1d2c904159" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromIssuanceOfDebt_9d5f6da3-0005-4c49-882f-aaa313bca0b9" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ProceedsFromIssuanceOfDebt"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_3ad67415-f63d-466d-90e9-9ada60489005" xlink:to="loc_us-gaap_ProceedsFromIssuanceOfDebt_9d5f6da3-0005-4c49-882f-aaa313bca0b9" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsOfStockIssuanceCosts_b0e9e70e-049f-49b8-83ad-3d54d00a0fcc" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PaymentsOfStockIssuanceCosts"/>
    <link:calculationArc order="6" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_3ad67415-f63d-466d-90e9-9ada60489005" xlink:to="loc_us-gaap_PaymentsOfStockIssuanceCosts_b0e9e70e-049f-49b8-83ad-3d54d00a0fcc" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RepaymentsOfDebt_2497e885-2563-4af8-9d81-a3c46f9b843f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RepaymentsOfDebt"/>
    <link:calculationArc order="7" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_3ad67415-f63d-466d-90e9-9ada60489005" xlink:to="loc_us-gaap_RepaymentsOfDebt_2497e885-2563-4af8-9d81-a3c46f9b843f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsOfDividends_ba0f8ec2-0977-4785-8516-1bd494734fac" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PaymentsOfDividends"/>
    <link:calculationArc order="8" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_3ad67415-f63d-466d-90e9-9ada60489005" xlink:to="loc_us-gaap_PaymentsOfDividends_ba0f8ec2-0977-4785-8516-1bd494734fac" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_82a8346b-1603-497b-883d-62f81a18d43f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_a8dc70f8-8b48-4392-af58-c2b06e57ad8f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_82a8346b-1603-497b-883d-62f81a18d43f" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_a8dc70f8-8b48-4392-af58-c2b06e57ad8f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_fdf9857a-332e-49bd-985d-2121bf5cc872" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_82a8346b-1603-497b-883d-62f81a18d43f" xlink:to="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_fdf9857a-332e-49bd-985d-2121bf5cc872" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_06f79587-a5fb-4d91-98f6-bf1074989c4a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_82a8346b-1603-497b-883d-62f81a18d43f" xlink:to="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_06f79587-a5fb-4d91-98f6-bf1074989c4a" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.htgc.com/role/CONSOLIDATEDSTATEMENTSOFCASHFLOWSParenthetical" xlink:type="simple" xlink:href="htgc-20251231.xsd#CONSOLIDATEDSTATEMENTSOFCASHFLOWSParenthetical"/>
  <link:calculationLink xlink:role="http://www.htgc.com/role/CONSOLIDATEDSTATEMENTSOFCASHFLOWSParenthetical" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_b52e61d1-008b-4a57-8a03-a6cd8b40db93" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedCash_e09013df-4a55-4556-b598-f5967fdc9888" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RestrictedCash"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_b52e61d1-008b-4a57-8a03-a6cd8b40db93" xlink:to="loc_us-gaap_RestrictedCash_e09013df-4a55-4556-b598-f5967fdc9888" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_10e58037-878b-4d5f-896c-e92a7bd45a3c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_b52e61d1-008b-4a57-8a03-a6cd8b40db93" xlink:to="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_10e58037-878b-4d5f-896c-e92a7bd45a3c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashHeldInForeignCurrency_9eb46563-cdc7-481d-b89f-b424c08ba87c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CashHeldInForeignCurrency"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_b52e61d1-008b-4a57-8a03-a6cd8b40db93" xlink:to="loc_us-gaap_CashHeldInForeignCurrency_9eb46563-cdc7-481d-b89f-b424c08ba87c" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.htgc.com/role/InvestmentsScheduleofDerivativeInstrumentsDetails" xlink:type="simple" xlink:href="htgc-20251231.xsd#InvestmentsScheduleofDerivativeInstrumentsDetails"/>
  <link:calculationLink xlink:role="http://www.htgc.com/role/InvestmentsScheduleofDerivativeInstrumentsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RealizedAndUnrealizedGainLossInvestmentAndDerivativeOperatingAfterTax_4f375ca6-d2f1-4332-b7a8-51bc8747a82e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RealizedAndUnrealizedGainLossInvestmentAndDerivativeOperatingAfterTax"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GainLossOnSaleOfDerivatives_88add67b-e175-4153-864d-4c255bc89bd3" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_GainLossOnSaleOfDerivatives"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_RealizedAndUnrealizedGainLossInvestmentAndDerivativeOperatingAfterTax_4f375ca6-d2f1-4332-b7a8-51bc8747a82e" xlink:to="loc_us-gaap_GainLossOnSaleOfDerivatives_88add67b-e175-4153-864d-4c255bc89bd3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_UnrealizedGainLossOnDerivatives_ffb3fa65-11f8-4b35-b68f-da8d5c2552f0" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_UnrealizedGainLossOnDerivatives"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_RealizedAndUnrealizedGainLossInvestmentAndDerivativeOperatingAfterTax_4f375ca6-d2f1-4332-b7a8-51bc8747a82e" xlink:to="loc_us-gaap_UnrealizedGainLossOnDerivatives_ffb3fa65-11f8-4b35-b68f-da8d5c2552f0" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.htgc.com/role/IncomeTaxesCashpaidforincometaxesnetofrefundsDetails" xlink:type="simple" xlink:href="htgc-20251231.xsd#IncomeTaxesCashpaidforincometaxesnetofrefundsDetails"/>
  <link:calculationLink xlink:role="http://www.htgc.com/role/IncomeTaxesCashpaidforincometaxesnetofrefundsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_htgc_IncomeTaxPaidStateAndLocalIncomeAndFranchiseTaxAfterRefundReceived_019be293-444d-7d3d-8c0a-ab4b171fd39b" xlink:href="htgc-20251231.xsd#htgc_IncomeTaxPaidStateAndLocalIncomeAndFranchiseTaxAfterRefundReceived"/>
    <link:loc xlink:type="locator" xlink:label="loc_htgc_IncomeTaxPaidStateAndLocalFranchiseTaxAfterRefundReceived_019be293-444d-7cc2-b23c-148886efb502" xlink:href="htgc-20251231.xsd#htgc_IncomeTaxPaidStateAndLocalFranchiseTaxAfterRefundReceived"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_htgc_IncomeTaxPaidStateAndLocalIncomeAndFranchiseTaxAfterRefundReceived_019be293-444d-7d3d-8c0a-ab4b171fd39b" xlink:to="loc_htgc_IncomeTaxPaidStateAndLocalFranchiseTaxAfterRefundReceived_019be293-444d-7cc2-b23c-148886efb502" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxPaidStateAndLocalAfterRefundReceived_019be293-444d-77ad-be00-939293d7fbfa" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeTaxPaidStateAndLocalAfterRefundReceived"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_htgc_IncomeTaxPaidStateAndLocalIncomeAndFranchiseTaxAfterRefundReceived_019be293-444d-7d3d-8c0a-ab4b171fd39b" xlink:to="loc_us-gaap_IncomeTaxPaidStateAndLocalAfterRefundReceived_019be293-444d-77ad-be00-939293d7fbfa" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxPaidForeignAfterRefundReceived_019be295-a626-7721-834a-2b1bb1279d2c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeTaxPaidForeignAfterRefundReceived"/>
    <link:loc xlink:type="locator" xlink:label="loc_htgc_IncomeTaxPaidForeignValueAddedTaxAfterRefundReceived_019be295-a626-73bf-9a4e-089b206eda12" xlink:href="htgc-20251231.xsd#htgc_IncomeTaxPaidForeignValueAddedTaxAfterRefundReceived"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeTaxPaidForeignAfterRefundReceived_019be295-a626-7721-834a-2b1bb1279d2c" xlink:to="loc_htgc_IncomeTaxPaidForeignValueAddedTaxAfterRefundReceived_019be295-a626-73bf-9a4e-089b206eda12" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxesPaidNet_019be295-d877-7754-8e64-d817ca44fa0f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeTaxesPaidNet"/>
    <link:loc xlink:type="locator" xlink:label="loc_htgc_IncomeTaxPaidFederalExciseAndIncomeTaxAfterRefundReceived_019be295-d877-7c1c-a2b1-c6d048e98d63" xlink:href="htgc-20251231.xsd#htgc_IncomeTaxPaidFederalExciseAndIncomeTaxAfterRefundReceived"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeTaxesPaidNet_019be295-d877-7754-8e64-d817ca44fa0f" xlink:to="loc_htgc_IncomeTaxPaidFederalExciseAndIncomeTaxAfterRefundReceived_019be295-d877-7c1c-a2b1-c6d048e98d63" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_htgc_IncomeTaxPaidStateAndLocalIncomeAndFranchiseTaxAfterRefundReceived_019be295-d877-7bf2-b5ea-6f168832518d" xlink:href="htgc-20251231.xsd#htgc_IncomeTaxPaidStateAndLocalIncomeAndFranchiseTaxAfterRefundReceived"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeTaxesPaidNet_019be295-d877-7754-8e64-d817ca44fa0f" xlink:to="loc_htgc_IncomeTaxPaidStateAndLocalIncomeAndFranchiseTaxAfterRefundReceived_019be295-d877-7bf2-b5ea-6f168832518d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxPaidForeignAfterRefundReceived_019be295-d877-7854-bef5-d70ad5adfb73" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeTaxPaidForeignAfterRefundReceived"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeTaxesPaidNet_019be295-d877-7754-8e64-d817ca44fa0f" xlink:to="loc_us-gaap_IncomeTaxPaidForeignAfterRefundReceived_019be295-d877-7854-bef5-d70ad5adfb73" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_htgc_IncomeTaxPaidFederalExciseAndIncomeTaxAfterRefundReceived_019be291-66b8-7143-a467-fb3b23989a47" xlink:href="htgc-20251231.xsd#htgc_IncomeTaxPaidFederalExciseAndIncomeTaxAfterRefundReceived"/>
    <link:loc xlink:type="locator" xlink:label="loc_htgc_IncomeTaxPaidFederalExciseTaxAfterRefundReceived_019be291-66b8-7533-b47b-59a87f0dbf59" xlink:href="htgc-20251231.xsd#htgc_IncomeTaxPaidFederalExciseTaxAfterRefundReceived"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_htgc_IncomeTaxPaidFederalExciseAndIncomeTaxAfterRefundReceived_019be291-66b8-7143-a467-fb3b23989a47" xlink:to="loc_htgc_IncomeTaxPaidFederalExciseTaxAfterRefundReceived_019be291-66b8-7533-b47b-59a87f0dbf59" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxPaidFederalAfterRefundReceived_019be291-66b8-7c1b-ba0a-e03df20b7a18" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeTaxPaidFederalAfterRefundReceived"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_htgc_IncomeTaxPaidFederalExciseAndIncomeTaxAfterRefundReceived_019be291-66b8-7143-a467-fb3b23989a47" xlink:to="loc_us-gaap_IncomeTaxPaidFederalAfterRefundReceived_019be291-66b8-7c1b-ba0a-e03df20b7a18" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.htgc.com/role/EarningsPerShareScheduleofBasicandDilutedEarningsPerShareDetails" xlink:type="simple" xlink:href="htgc-20251231.xsd#EarningsPerShareScheduleofBasicandDilutedEarningsPerShareDetails"/>
  <link:calculationLink xlink:role="http://www.htgc.com/role/EarningsPerShareScheduleofBasicandDilutedEarningsPerShareDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic_9b231935-0793-4236-88c3-ae7b68d05546" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentCompanyDividendDistribution_65c232a2-7442-4d27-a997-9f4cf09b4b05" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InvestmentCompanyDividendDistribution"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic_9b231935-0793-4236-88c3-ae7b68d05546" xlink:to="loc_us-gaap_InvestmentCompanyDividendDistribution_65c232a2-7442-4d27-a997-9f4cf09b4b05" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_UndistributedEarnings_df264b7f-f6e9-4eae-9ec9-472f2acc68ab" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_UndistributedEarnings"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic_9b231935-0793-4236-88c3-ae7b68d05546" xlink:to="loc_us-gaap_UndistributedEarnings_df264b7f-f6e9-4eae-9ec9-472f2acc68ab" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersDiluted_019b3688-2a10-7a74-a4c1-287946f042f4" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetIncomeLossAvailableToCommonStockholdersDiluted"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic_019b3688-2a10-7dac-b492-a47c0ba297fd" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersDiluted_019b3688-2a10-7a74-a4c1-287946f042f4" xlink:to="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic_019b3688-2a10-7dac-b492-a47c0ba297fd" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DilutiveSecuritiesEffectOnBasicEarningsPerShareOther_019b3688-2a10-70f7-91cd-c7d08d1c14d0" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DilutiveSecuritiesEffectOnBasicEarningsPerShareOther"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersDiluted_019b3688-2a10-7a74-a4c1-287946f042f4" xlink:to="loc_us-gaap_DilutiveSecuritiesEffectOnBasicEarningsPerShareOther_019b3688-2a10-70f7-91cd-c7d08d1c14d0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_UndistributedEarningsLossAvailableToCommonShareholdersBasic_1ef3f7a2-d5f1-47e9-b342-d0e9b9bd386b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_UndistributedEarningsLossAvailableToCommonShareholdersBasic"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_da599f95-e11c-48b4-b9b0-a40b91845f86" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetIncomeLoss"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_UndistributedEarningsLossAvailableToCommonShareholdersBasic_1ef3f7a2-d5f1-47e9-b342-d0e9b9bd386b" xlink:to="loc_us-gaap_NetIncomeLoss_da599f95-e11c-48b4-b9b0-a40b91845f86" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentCompanyDividendDistribution_391af2d4-e45a-430c-a319-5d6a5fc5b4d8" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InvestmentCompanyDividendDistribution"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_UndistributedEarningsLossAvailableToCommonShareholdersBasic_1ef3f7a2-d5f1-47e9-b342-d0e9b9bd386b" xlink:to="loc_us-gaap_InvestmentCompanyDividendDistribution_391af2d4-e45a-430c-a319-5d6a5fc5b4d8" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_355a2a4f-af5e-4c7c-b362-b1d014a1cd8a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_ee3cafec-023e-469e-8170-528f88d4fdf3" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingBasic"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_355a2a4f-af5e-4c7c-b362-b1d014a1cd8a" xlink:to="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_ee3cafec-023e-469e-8170-528f88d4fdf3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncrementalCommonSharesAttributableToConversionOfDebtSecurities_b17df528-10d8-437f-88d5-647d56d70548" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncrementalCommonSharesAttributableToConversionOfDebtSecurities"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_355a2a4f-af5e-4c7c-b362-b1d014a1cd8a" xlink:to="loc_us-gaap_IncrementalCommonSharesAttributableToConversionOfDebtSecurities_b17df528-10d8-437f-88d5-647d56d70548" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements_019b3687-aca6-7e3e-b3d1-435662730711" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_355a2a4f-af5e-4c7c-b362-b1d014a1cd8a" xlink:to="loc_us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements_019b3687-aca6-7e3e-b3d1-435662730711" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.htgc.com/role/FinancialHighlightsDetails" xlink:type="simple" xlink:href="htgc-20251231.xsd#FinancialHighlightsDetails"/>
  <link:calculationLink xlink:role="http://www.htgc.com/role/FinancialHighlightsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentCompanyInvestmentIncomeLossFromOperationsPerShare_cb6b7b2c-a37c-4d52-a4d0-61ea84e9a521" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InvestmentCompanyInvestmentIncomeLossFromOperationsPerShare"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentCompanyGainLossOnInvestmentPerShare_01e50d2d-61dd-4c5b-80e6-050fd9b6ce09" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InvestmentCompanyGainLossOnInvestmentPerShare"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InvestmentCompanyInvestmentIncomeLossFromOperationsPerShare_cb6b7b2c-a37c-4d52-a4d0-61ea84e9a521" xlink:to="loc_us-gaap_InvestmentCompanyGainLossOnInvestmentPerShare_01e50d2d-61dd-4c5b-80e6-050fd9b6ce09" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.htgc.com/role/CommitmentsandContingenciesScheduleofAdditionalInformationonUnencumberedUnfundedCommitmentsDetails" xlink:type="simple" xlink:href="htgc-20251231.xsd#CommitmentsandContingenciesScheduleofAdditionalInformationonUnencumberedUnfundedCommitmentsDetails"/>
  <link:calculationLink xlink:role="http://www.htgc.com/role/CommitmentsandContingenciesScheduleofAdditionalInformationonUnencumberedUnfundedCommitmentsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentCompanyFinancialCommitmentToInvesteeFutureAmount_a175b510-6324-4140-ad3b-a97fc84c30af" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InvestmentCompanyFinancialCommitmentToInvesteeFutureAmount"/>
    <link:loc xlink:type="locator" xlink:label="loc_htgc_UnfundedCommitmentsDueInFourthYear_01e6db13-9ba8-4747-8229-99cc70089368" xlink:href="htgc-20251231.xsd#htgc_UnfundedCommitmentsDueInFourthYear"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InvestmentCompanyFinancialCommitmentToInvesteeFutureAmount_a175b510-6324-4140-ad3b-a97fc84c30af" xlink:to="loc_htgc_UnfundedCommitmentsDueInFourthYear_01e6db13-9ba8-4747-8229-99cc70089368" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_htgc_UnfundedCommitmentsDueInSecondYear_d76d4e11-fef0-40b7-a3fa-c292595261ce" xlink:href="htgc-20251231.xsd#htgc_UnfundedCommitmentsDueInSecondYear"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InvestmentCompanyFinancialCommitmentToInvesteeFutureAmount_a175b510-6324-4140-ad3b-a97fc84c30af" xlink:to="loc_htgc_UnfundedCommitmentsDueInSecondYear_d76d4e11-fef0-40b7-a3fa-c292595261ce" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_htgc_UnfundedCommitmentsDueInFifthYear_1868896e-60af-4836-ac53-d2a4ac0bb5fb" xlink:href="htgc-20251231.xsd#htgc_UnfundedCommitmentsDueInFifthYear"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InvestmentCompanyFinancialCommitmentToInvesteeFutureAmount_a175b510-6324-4140-ad3b-a97fc84c30af" xlink:to="loc_htgc_UnfundedCommitmentsDueInFifthYear_1868896e-60af-4836-ac53-d2a4ac0bb5fb" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_htgc_UnfundedCommitmentsDueInPriorYear_ac7b4e55-9e92-497a-b5e9-434736ba649b" xlink:href="htgc-20251231.xsd#htgc_UnfundedCommitmentsDueInPriorYear"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InvestmentCompanyFinancialCommitmentToInvesteeFutureAmount_a175b510-6324-4140-ad3b-a97fc84c30af" xlink:to="loc_htgc_UnfundedCommitmentsDueInPriorYear_ac7b4e55-9e92-497a-b5e9-434736ba649b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_htgc_UnfundedCommitmentsDueInThirdYear_f48aebf6-e00f-46a8-ad72-51d2cf52c5b8" xlink:href="htgc-20251231.xsd#htgc_UnfundedCommitmentsDueInThirdYear"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InvestmentCompanyFinancialCommitmentToInvesteeFutureAmount_a175b510-6324-4140-ad3b-a97fc84c30af" xlink:to="loc_htgc_UnfundedCommitmentsDueInThirdYear_f48aebf6-e00f-46a8-ad72-51d2cf52c5b8" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_htgc_UnfundedCommitmentsDueInSixthYear_08067abc-5746-40c2-90b3-5270f5562df6" xlink:href="htgc-20251231.xsd#htgc_UnfundedCommitmentsDueInSixthYear"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InvestmentCompanyFinancialCommitmentToInvesteeFutureAmount_a175b510-6324-4140-ad3b-a97fc84c30af" xlink:to="loc_htgc_UnfundedCommitmentsDueInSixthYear_08067abc-5746-40c2-90b3-5270f5562df6" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_htgc_UnfundedCommitmentsDueInOneYear_eb1f378f-cd34-4963-9761-0f89f4428fa7" xlink:href="htgc-20251231.xsd#htgc_UnfundedCommitmentsDueInOneYear"/>
    <link:calculationArc order="7" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InvestmentCompanyFinancialCommitmentToInvesteeFutureAmount_a175b510-6324-4140-ad3b-a97fc84c30af" xlink:to="loc_htgc_UnfundedCommitmentsDueInOneYear_eb1f378f-cd34-4963-9761-0f89f4428fa7" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.htgc.com/role/CommitmentsandContingenciesScheduleofAdditionalInformationonUnencumberedUnfundedCommitmentsDetails_1" xlink:type="simple" xlink:href="htgc-20251231.xsd#CommitmentsandContingenciesScheduleofAdditionalInformationonUnencumberedUnfundedCommitmentsDetails_1"/>
  <link:calculationLink xlink:role="http://www.htgc.com/role/CommitmentsandContingenciesScheduleofAdditionalInformationonUnencumberedUnfundedCommitmentsDetails_1" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentCompanyFinancialCommitmentToInvesteeFutureAmount_26c9b1ee-0b40-4383-bc94-53df0b7ce8b6" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InvestmentCompanyFinancialCommitmentToInvesteeFutureAmount"/>
    <link:loc xlink:type="locator" xlink:label="loc_htgc_UnfundedCommitmentsDueInSixthYear_042bcd10-4446-4d49-8bc3-8efd9ca827bd" xlink:href="htgc-20251231.xsd#htgc_UnfundedCommitmentsDueInSixthYear"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InvestmentCompanyFinancialCommitmentToInvesteeFutureAmount_26c9b1ee-0b40-4383-bc94-53df0b7ce8b6" xlink:to="loc_htgc_UnfundedCommitmentsDueInSixthYear_042bcd10-4446-4d49-8bc3-8efd9ca827bd" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_htgc_UnfundedCommitmentsDueInEighthYear_a4d69e97-c5a4-4c27-9e91-901fd82606a7" xlink:href="htgc-20251231.xsd#htgc_UnfundedCommitmentsDueInEighthYear"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InvestmentCompanyFinancialCommitmentToInvesteeFutureAmount_26c9b1ee-0b40-4383-bc94-53df0b7ce8b6" xlink:to="loc_htgc_UnfundedCommitmentsDueInEighthYear_a4d69e97-c5a4-4c27-9e91-901fd82606a7" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.htgc.com/role/CommitmentsandContingenciesScheduleofContractualObligationsDetails" xlink:type="simple" xlink:href="htgc-20251231.xsd#CommitmentsandContingenciesScheduleofContractualObligationsDetails"/>
  <link:calculationLink xlink:role="http://www.htgc.com/role/CommitmentsandContingenciesScheduleofContractualObligationsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ContractualObligation_57ac076f-a8b1-4d97-a56e-3c5e6d02ea0d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ContractualObligation"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ContractualObligationDueInSecondAndThirdYear_dd4a6f3b-4e26-452d-9789-1ea3a22437a2" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ContractualObligationDueInSecondAndThirdYear"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_ContractualObligation_57ac076f-a8b1-4d97-a56e-3c5e6d02ea0d" xlink:to="loc_us-gaap_ContractualObligationDueInSecondAndThirdYear_dd4a6f3b-4e26-452d-9789-1ea3a22437a2" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ContractualObligationDueAfterFifthYear_7889312f-2a80-4dc4-84c5-377012070495" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ContractualObligationDueAfterFifthYear"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_ContractualObligation_57ac076f-a8b1-4d97-a56e-3c5e6d02ea0d" xlink:to="loc_us-gaap_ContractualObligationDueAfterFifthYear_7889312f-2a80-4dc4-84c5-377012070495" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ContractualObligationDueInFourthAndFifthYear_10d1d5bc-de15-48cd-a932-782492989ed0" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ContractualObligationDueInFourthAndFifthYear"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_ContractualObligation_57ac076f-a8b1-4d97-a56e-3c5e6d02ea0d" xlink:to="loc_us-gaap_ContractualObligationDueInFourthAndFifthYear_10d1d5bc-de15-48cd-a932-782492989ed0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ContractualObligationDueInNextTwelveMonths_3c50d599-568a-4085-97c7-8d54e2c22e86" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ContractualObligationDueInNextTwelveMonths"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_ContractualObligation_57ac076f-a8b1-4d97-a56e-3c5e6d02ea0d" xlink:to="loc_us-gaap_ContractualObligationDueInNextTwelveMonths_3c50d599-568a-4085-97c7-8d54e2c22e86" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_05d38a65-985b-4e70-9128-f11f5a7f2921" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue"/>
    <link:loc xlink:type="locator" xlink:label="loc_htgc_LesseeOperatingLeaseLiabilityToBePaidYearFourAndFive_5771ffb8-5c6e-4473-bc22-cd6b4bcb9a10" xlink:href="htgc-20251231.xsd#htgc_LesseeOperatingLeaseLiabilityToBePaidYearFourAndFive"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_05d38a65-985b-4e70-9128-f11f5a7f2921" xlink:to="loc_htgc_LesseeOperatingLeaseLiabilityToBePaidYearFourAndFive_5771ffb8-5c6e-4473-bc22-cd6b4bcb9a10" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_htgc_LesseeOperatingLeaseLiabilityToBePaidYearTwoAndThree_a26c8e6c-10a7-4825-87fd-6f10dafb96a6" xlink:href="htgc-20251231.xsd#htgc_LesseeOperatingLeaseLiabilityToBePaidYearTwoAndThree"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_05d38a65-985b-4e70-9128-f11f5a7f2921" xlink:to="loc_htgc_LesseeOperatingLeaseLiabilityToBePaidYearTwoAndThree_a26c8e6c-10a7-4825-87fd-6f10dafb96a6" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths_1d6c9c11-5fc5-40a5-b05d-ab33bf4da814" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_05d38a65-985b-4e70-9128-f11f5a7f2921" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths_1d6c9c11-5fc5-40a5-b05d-ab33bf4da814" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueAfterYearFive_380c0f1c-9839-44b1-aec5-7d424cec394f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueAfterYearFive"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_05d38a65-985b-4e70-9128-f11f5a7f2921" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueAfterYearFive_380c0f1c-9839-44b1-aec5-7d424cec394f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebt_0f51cfda-1350-4e67-88ca-7ba8806aede5" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LongTermDebt"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalAfterYearFive_972fd05e-c9fb-4deb-b33d-691092090d94" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalAfterYearFive"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LongTermDebt_0f51cfda-1350-4e67-88ca-7ba8806aede5" xlink:to="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalAfterYearFive_972fd05e-c9fb-4deb-b33d-691092090d94" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInNextTwelveMonths_827139ce-bcf6-476e-961a-d8185c3bfa54" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInNextTwelveMonths"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LongTermDebt_0f51cfda-1350-4e67-88ca-7ba8806aede5" xlink:to="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInNextTwelveMonths_827139ce-bcf6-476e-961a-d8185c3bfa54" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtMaturingInYearsTwoAndThree_a22424f5-b0c7-4edb-8b98-541fa8570582" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LongTermDebtMaturingInYearsTwoAndThree"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LongTermDebt_0f51cfda-1350-4e67-88ca-7ba8806aede5" xlink:to="loc_us-gaap_LongTermDebtMaturingInYearsTwoAndThree_a22424f5-b0c7-4edb-8b98-541fa8570582" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtMaturingInYearsFourAndFive_f5866d0c-efc9-48f0-a474-0bf1dc94702c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LongTermDebtMaturingInYearsFourAndFive"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LongTermDebt_0f51cfda-1350-4e67-88ca-7ba8806aede5" xlink:to="loc_us-gaap_LongTermDebtMaturingInYearsFourAndFive_f5866d0c-efc9-48f0-a474-0bf1dc94702c" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.htgc.com/role/CommitmentsandContingenciesScheduleofFutureMinimumLeasePaymentsunderOperatingLeasesandReconciliationtoOperatingLeaseLiabilityDetails" xlink:type="simple" xlink:href="htgc-20251231.xsd#CommitmentsandContingenciesScheduleofFutureMinimumLeasePaymentsunderOperatingLeasesandReconciliationtoOperatingLeaseLiabilityDetails"/>
  <link:calculationLink xlink:role="http://www.htgc.com/role/CommitmentsandContingenciesScheduleofFutureMinimumLeasePaymentsunderOperatingLeasesandReconciliationtoOperatingLeaseLiabilityDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_45c23d68-5f91-466e-88ca-0884b051f95f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiability_df5bfd68-247f-41ea-a96b-62b69a107597" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingLeaseLiability"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_45c23d68-5f91-466e-88ca-0884b051f95f" xlink:to="loc_us-gaap_OperatingLeaseLiability_df5bfd68-247f-41ea-a96b-62b69a107597" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount_00b75463-721c-4445-a1f4-e93110b4718e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_45c23d68-5f91-466e-88ca-0884b051f95f" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount_00b75463-721c-4445-a1f4-e93110b4718e" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.htgc.com/role/CommitmentsandContingenciesScheduleofFutureMinimumLeasePaymentsunderOperatingLeasesandReconciliationtoOperatingLeaseLiabilityDetails_1" xlink:type="simple" xlink:href="htgc-20251231.xsd#CommitmentsandContingenciesScheduleofFutureMinimumLeasePaymentsunderOperatingLeasesandReconciliationtoOperatingLeaseLiabilityDetails_1"/>
  <link:calculationLink xlink:role="http://www.htgc.com/role/CommitmentsandContingenciesScheduleofFutureMinimumLeasePaymentsunderOperatingLeasesandReconciliationtoOperatingLeaseLiabilityDetails_1" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_1cadd76b-bcf8-4326-92a0-cdd5e424ab55" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths_41338c32-800a-46d9-9a9d-15086a822cef" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_1cadd76b-bcf8-4326-92a0-cdd5e424ab55" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths_41338c32-800a-46d9-9a9d-15086a822cef" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo_ff06633f-43c9-4c09-829b-bd24597feada" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_1cadd76b-bcf8-4326-92a0-cdd5e424ab55" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo_ff06633f-43c9-4c09-829b-bd24597feada" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree_997f1110-2071-4136-9d22-691a34267a60" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_1cadd76b-bcf8-4326-92a0-cdd5e424ab55" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree_997f1110-2071-4136-9d22-691a34267a60" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_htgc_LesseeOperatingLeaseLiabilityPaymentsDueAfterYearThree_7fed9351-a859-4214-944d-51d6e767d399" xlink:href="htgc-20251231.xsd#htgc_LesseeOperatingLeaseLiabilityPaymentsDueAfterYearThree"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_1cadd76b-bcf8-4326-92a0-cdd5e424ab55" xlink:to="loc_htgc_LesseeOperatingLeaseLiabilityPaymentsDueAfterYearThree_7fed9351-a859-4214-944d-51d6e767d399" xlink:type="arc"/>
  </link:calculationLink>
</link:linkbase>
